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Hey guys, need help with possible autoimmune/adrenal/leaky gut/thryoid issue.

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Updated about 1 hour ago
Created December 23, 2013 at 6:12 PM

Hi guys, my name is Jay and I'm 29 years old. My story of suffering with illness goes back to my earliest memories, with anxiety and panic attacks. Severe emotional trauma at age 16 (my parents' totally unexpected divorce) magnified this issue. It was then compounded and magnified by orders of magnitude after awful experiences on psychedelic mushrooms at age 18, a.k.a. "bad trips."

After this, my health hit rock bottom, as I was entering states of severe anxiety, depression, and reacting to anything and everything I put in my body.

Naturally, I did what I thought was right - I visited psychiatrists. Every single medication yielded the same results: a few days of hypomania, or feeling vibrant and full of energy, followed by a bad, bad crash. (I now know this mostly to be adrenal related crashes.) It was a nightmare, and still can be if my diet slips.

Because of the inability of medications to help, I turned to drinking, and heavily. It was nothing for me to down 6, 8, or even 14 beers in a night. I didn't realize the damage this might cause at my young age, but I sure do now! I suffered from a severe Candida issue (now seemingly under control through diet, probiotics, and elimination of sugar and all alcohol.), and the drinking also heavily taxed my body all around.

One thing that was always very clear during my years of illness was that I would usually feel pretty darn close to a decent mood with decent energy until I ate something. It didn't seem to matter what in the world it was - after I'd eat, I'd crash, and my energy would plummet. This led to more drinking out of frustration, and eventually to opiates.

I've now been clean of opiates for over 1 year, and I no longer drink. But it's obvious that I have some serious leaky gut issues going on, along with adrenal issues, and quite likely thyroid issues as well. I've been eating a strict Paleo diet, as I noticed grains make me exhausted beyond all belief and depressed, including oats. Beans give me anxiety and crying spells. But I also have other sensitivities, too. Eggs/egg whites bring about crushing depression, and I'm now trying to figure out which other foods do as well. I'd like to eat raw salads, but I get horribly exhausted after eating raw veggies as well.

My reaction is interesting in nature, and I'd like to find someone who knows what it might be. I currently can handle sweet potatoes without issue, as well as ground turkey, cooked to a soft texture in coconut oil. Eggs, steamed asparagus, steamed broccoli, bananas, and who knows what else will be added to the list will give me a strange reaction. I'll feel flushing within my body, fall into bad depression and anxiety, my body will feel hot and feverish, and eventually I'll end up in a crying spell. I'm guessing this may be autoimmune, as if my body is seeing certain foods as foreign invaders, attacking healthy tissue, and a mass of stress chemicals are released. I do know that tears are a way that the body releases stress chemicals, and I do feel a bit better after the crying spells, but it's downright scary.

I currently take Ultimate Flora probiotics in the morning, magnesium, 1,000 mg Ester C vitamin C nightly, vitamin D-3 and will soon begin consuming bone broth daily to try and assist my leaky gut issues, if that's what this is.

Sorry for the novel - any help is appreciated!

96440612cf0fcf366bf5ad8f776fca84
17103 · December 25, 2013 at 11:40 AM

Another thing came to mind about low energy, perhaps you've issues with your mitochondria as well in addition to adrenal/thyroid issues. You might try some creatine monohydride which easily gets converted to ATP, try a little bit and see what effect it has, and also get some PQQ which helps increase mitochondrial function - later on when you can both cardio and weight lifting can help multiply them.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:57 PM

This might or might not help with neurotransmitters, 5000mg L-Tyrosine in the morning, 500mg 5HTP at night... with B6, Calcium, Vitamin C, cystine, folate - the 1st two are supplements that affect serotonin/dopamine production; the rest you'd likely get from food. But avoid this until you know whether you have thyroid issues, as L-Tyrosine will cause more T3/T4 to be created. Don't just take one without the other.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:55 PM

To kill off the stress reaction, you'll want something like 800mg of phosphatidyl serine (this is quite a lot, and yes, you'll finish a whole bottle in a week easily), along with eleuthero, ashwagandha, rhodiola. You may feel sleepy with this combination, that's fine, you'll want your adrenals to recover. I used this myself recently when I had a lot of stress and it helped a lot.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:50 PM

Sorry for the multiple comments (I can't just write a large reply, and the comments will be out of order). For adrenals, you can do this. In the morning take a teaspoon of seasalt in water, maybe add some lemon juice to that. Salt is needed by the adrenals.

Then for a week and no more, take half a teaspoon or so of licorice root (not the candy) in warm water as a tea. This helps to recycle cortisol. Don't take too much or for too long as it will raise your blood pressure.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:48 PM

Yes, those sound like both adrenal and thyroid issues. Most CW doctors won't bother with an ASI (Adrenal Stress Index where you take saliva samples 3x-4x a day to measure adrenal response), but you could convince them to do a full thyroid panel - might be an autoimmune condition like Hashimotos, if so be very careful of iodine/selenium supplementation and shellfish/seaweed.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:44 PM

Oh wow, I've never heard of anyone reacting to glutamine. Was it pure glutamine, or did it have fillers (I'm hoping you reacted to the fillers - pills usually have them, while the powders are usually pure.) Either way, I'm not asking you to try glutamine again, it's just that it can have a healing effect independent of bone broth... oh well.

E61198ee39f35db55a6da97d681947f0
0 · December 23, 2013 at 7:17 PM

Maybe fixing your circadian rhythm will help with the underlying problems some, too.

E61198ee39f35db55a6da97d681947f0
0 · December 23, 2013 at 7:17 PM

(You might also try tender, high-fat/lots of connective tissue/matrix material stews of grass-fed/pastured meats. Those can even be added to bone broths and might be easier to digest. Lots of animal flesh/animal fat % of diet for awhile seems not uncommon in those with digestive problems (sounds somewhat likely; even if it's an autoimmune/adrenal/thyroid issue, addressing diet/healing the gut should help some by themselves, even if the autoimmune/adrenal/thyroid/whatever it is has been causing gut dysbiosis)

E61198ee39f35db55a6da97d681947f0
0 · December 23, 2013 at 7:11 PM

If it's possible, try to sleep from 9-10 p.m. to 6-7 a.m. in a completely darkened room and fix circadian rhythm (even if it takes awhile) - circadian rhythms look very, very important to pretty much all overall health. You can look for another post I wrote in much more detail re: circadian rhythms in response to another question. Daily daytime light/sunshine exposure with light walks might be a good start.

Good luck! I hope that you get better. :)

E61198ee39f35db55a6da97d681947f0
0 · December 23, 2013 at 7:09 PM

Have you tried small amounts (0.25 lb/ week) of grassfed beef liver (pate, and mashed foods in general, may be far easier to digest if there are strange digestive reactions)

You can also try shellfish if tolerable for superior, dense concentrations of nutrients that would likely help.

E61198ee39f35db55a6da97d681947f0
0 · December 23, 2013 at 7:09 PM

you might try adding a generous amount to warm bone/marrow broths for awhile. Drink enough fluids/clean water, if it doesn't make you feel bad. If taking D3, also take K2 (there's been a good bit of research regarding targeting vitamin D levels that are too high, by the way, so it may be wise to monitor your levels with supplementation; you can find more on vitamin D/oversupplementation/optimal range on the Perfect Health Diet and Chris Kresser's sites. K2 might be protective against D toxicity, though.)

E61198ee39f35db55a6da97d681947f0
0 · December 23, 2013 at 7:04 PM

Have you gotten blood tests for your thyroid or Hashimoto's/other autoimmune antibody titers? You might be able to use natural thyroid hormone if you have hypo/hyperthyroid. Syontix (

http://syontix.com/why-raw-garlic-may-be-your-guts-best-friend/) had an interesting article regarding garlic/water or lime juice infusions to break up pathogenic bacteria while supplementing with probiotics. You could consider getting a Metametrix stool DNA/RNA test, also. Great Lakes gelatin seems to help with similar neurological/gut-linked issues, too -

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0 · December 26, 2013 at 9:27 PM

Oh, and I also must mention that any amount of iodine supplementation will send me flying SKY HIGH with insane anxiety, body tingles, heart palpiations/tachycardia, sweating, etc etc. This includes even small doses of Kelp. Here's a fantastic article I just found on Stopthethyroidmadness.com:

http://www.stopthethyroidmadness.com/stories-of-others/patricias-story/ These are the exact type of words I need to hear, as they describe my situation perfectly!

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0 · December 26, 2013 at 9:24 PM

Thanks for the replies, Ray. Tyrosine makes me crash (adrenal related, I think), as does licorice root. I already take salt each morning, and these are things that have helped. Your mention of Hashimoto's is something I've been looking into and boy, does it make a LOT of sense. I must also thank you for your mention of free-thiol foods! I'm really seeing improvement in my depression since staying away from them! I am, however, still having bouts of bad exhaustion. I've been extremely tired ALL day long today and haven't gotten anything done =( But at least my mood is decent =)

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0 · December 24, 2013 at 5:31 PM

Hmm...sorry for that weird looking double post. Not sure what happened there :/

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0 · December 24, 2013 at 4:50 AM

Thanks for the reply, ray! Your mention of foods high in free thiols is highly interesting. I found this website listing foods with and without, and I gotta say it lines up pretty darn well with my reactions:

http://www.livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list/ I've tried L-Glutamine in the past...it caused horrific anxiety for me for whatever reason. (I am somewhere on the Asperger's spectrum; perhaps this is involved.) As for my belief that I have adrenal/thyroid issues, I crash after exercise which I must keep to a minimum, I can fall into states of extreme exhaustion at times, my body temperature seems to fluctuate from hot to cold as noticed in my extremities, I've always suffered from air hunger, etc. No thinning of hair or of eyebrows. My wife is going to help me give the GAPS introduction a try, and I'll begin consuming bone broth multiple times daily. Thanks so much for the help =)

,

Thanks for the reply, ray! Your mention of foods high in free thiols is highly interesting. I found this website listing foods with and without, and I gotta say it lines up pretty darn well with my reactions:

http://www.livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list/ I've tried L-Glutamine in the past...it caused horrific anxiety for me for whatever reason. (I am somewhere on the Asperger's spectrum; perhaps this is involved.) As for my belief that I have adrenal/thyroid issues, I crash after exercise which I must keep to a minimum, I can fall into states of extreme exhaustion at times, my body temperature seems to fluctuate from hot to cold as noticed in my extremities, etc. No thinning of hair or of eyebrows. My wife is going to help me give the GAPS introduction a try, and I'll begin consuming bone broth multiple times daily. Thanks so much for the help =)

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:57 PM

This might or might not help with neurotransmitters, 5000mg L-Tyrosine in the morning, 500mg 5HTP at night... with B6, Calcium, Vitamin C, cystine, folate - the 1st two are supplements that affect serotonin/dopamine production; the rest you'd likely get from food. But avoid this until you know whether you have thyroid issues, as L-Tyrosine will cause more T3/T4 to be created. Don't just take one without the other.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:48 PM

Yes, those sound like both adrenal and thyroid issues. Most CW doctors won't bother with an ASI (Adrenal Stress Index where you take saliva samples 3x-4x a day to measure adrenal response), but you could convince them to do a full thyroid panel - might be an autoimmune condition like Hashimotos, if so be very careful of iodine/selenium supplementation and shellfish/seaweed.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:50 PM

Sorry for the multiple comments (I can't just write a large reply, and the comments will be out of order). For adrenals, you can do this. In the morning take a teaspoon of seasalt in water, maybe add some lemon juice to that. Salt is needed by the adrenals.

Then for a week and no more, take half a teaspoon or so of licorice root (not the candy) in warm water as a tea. This helps to recycle cortisol. Don't take too much or for too long as it will raise your blood pressure.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:44 PM

Oh wow, I've never heard of anyone reacting to glutamine. Was it pure glutamine, or did it have fillers (I'm hoping you reacted to the fillers - pills usually have them, while the powders are usually pure.) Either way, I'm not asking you to try glutamine again, it's just that it can have a healing effect independent of bone broth... oh well.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 24, 2013 at 2:55 PM

To kill off the stress reaction, you'll want something like 800mg of phosphatidyl serine (this is quite a lot, and yes, you'll finish a whole bottle in a week easily), along with eleuthero, ashwagandha, rhodiola. You may feel sleepy with this combination, that's fine, you'll want your adrenals to recover. I used this myself recently when I had a lot of stress and it helped a lot.

96440612cf0fcf366bf5ad8f776fca84
17103 · December 25, 2013 at 11:40 AM

Another thing came to mind about low energy, perhaps you've issues with your mitochondria as well in addition to adrenal/thyroid issues. You might try some creatine monohydride which easily gets converted to ATP, try a little bit and see what effect it has, and also get some PQQ which helps increase mitochondrial function - later on when you can both cardio and weight lifting can help multiply them.

96440612cf0fcf366bf5ad8f776fca84
0
17103 · December 23, 2013 at 11:08 PM

You'll want the D3 in the morning. C you'll want to split up and take 2x-3x a day since we don't store it well, magnesium should be taken at night. Something about that list: eggs, broccoli, asparagus, bananas says to me sulfur/thiol intolerance. Might be something to look into.

http://www.bionatures.com/foods-high-in-sulfur/ mentions a lot of these on your list too. There was a recent question here about thyols, might want to seek that out.

Bone broth will help leaky gut, but get about 4000-5000mg of L-Glutamine a day - preferably as a powder.

What things make you believe you have adrenal/thyroid issues? Do you have issues sleeping/staying awake, groggy in the morning, rapid heart beat, cold hands/feet or general cold/heat intolerance, thinning hair or outer 3rd of eyebrows?

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