High Progesterone & Estradiol in Male. Causes & Cures?

by 288 · April 02, 2011 at 11:17 PM

I've done an adrenal fatigue salivary test. And my results have shown some issues with Cortisol and melatonin. However, the biggest problem was salivary Estradiol and Progesterone which were way above recommended levels (8.1 PG/ml, 213 PG/ml).

I have tried looking for an answer online, but I haven't found anything useful so far. Any clues as to what the cause of this could be? And what to do about it?

I've been strict paleo for 2 years now, lean and fit. I decided to do the adrenal stress test since I've been having issues with managing my stress lately. This, I believe, has led me to gain abdominal fat, decrease my sleep quality (I wake up tired), and decrease my overall energy and mood levels.

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25189 · April 02, 2011 at 07:32 PM

Few issues here......the estrogen being up.....is it E1 E2 or E3? My bet its E2. And it could be because of aromatase induction. The progesterone elevation could be from several issues. Low T, real low DHT, or it could be from transient BPH. High progesterone in males is associated with low sex drive, bad sleep (low melatonin), shrinking manhood, and elevated BP. This really needs to be sorted out by a doc. You need to see one. Progesterone and cortisol elevation in men are very common things we see.........so don't fret get a consult. Good Luck

22684 · April 02, 2011 at 11:11 PM

Avoid phytoestrogen rich foods. A quick google search will list them for you. I bet you're eating more than one. Also reference the jack my testosterone thread I detailed the food TO eat and why.

791 · April 02, 2011 at 09:20 PM

The accuracy of salivary hormone testing is debatable: http://www.aetna.com/cpb/medical/data/600_699/0608.html

[QUOTE]  Aetna considers salivary tests of dehydroepiandrosterone (DHEA), estrogen, melatonin, progesterone, or testosterone experimental and investigational for the screening, diagnosis, or monitoring of menopause or diseases related to aging, or any other indications because these tests have not been proven to be valid alternatives to serum tests.

That said, if you confirm high progesterone via serum hormone testing, that can indicate a deficit in the 5a reductase type 2 isoenzyme, which is responsible for transforming progesterone into the neurosteroid allopregnanolone. Are you depressed at all?

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