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Antioxidants (Vitamin C) stop exercise induced increased insulin sensitivity

by (2407)
Updated October 25, 2014 at 3:44 AM
Created September 11, 2012 at 9:41 AM

http://www.ncbi.nlm.nih.gov/m/pubmed/19433800/

As we know, exercise increases insulin sensitivity. This study says vitamin C and antioxidants negate that effect.

Apparently it shuts down the benefits of autophagy too. http://metamodern.com/2010/09/26/antioxidants-block-cell-repair/

So does this mean we should not take Vit C?

Or should we time intake appropriately? The study doesn't mention timing. I wonder if taking Vit C at night, long after exercise, and not during the autophagy phase of a fast, would help?

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1005 · April 03, 2014 at 5:50 AM

You generally want a diet high in antioxidants if you exercise regularly. You'll still get the same benefits (possibly with greater performance metrics) with less damage to your body, so you can get up and do it again the next day.

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60 · April 03, 2014 at 4:11 AM

Makes sense. Its stressed based, same as the adaptions in the liver. Just don't take artificially high dose supplements right before exercise. Is there not any vit c in your food?

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20908 · November 07, 2012 at 4:12 PM

I would inagine there no/little effect. The hormetic stress of exercise is the oxidative damage that results from all of the free radicals created during combustion. That's what the antioxidants undo.

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2407 · November 07, 2012 at 6:00 AM

Without INSULIN (not insult, lol)

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2407 · November 07, 2012 at 5:59 AM

Do antioxidants stop the non-insulin mediated glucose uptake process which is stimulated by training? (GLUT is mobilized to the surface of muscle cells to take sugar in without insulin to stimulate the process) ??

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24538 · September 25, 2012 at 9:42 PM

Hey, so my German host father wasn't just being a controlling weirdo when he chastised me for eating my St. Nicolas Day mandarin orange as a late night snack, and suggested I save it for morning.

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3 Answers

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20908 · November 06, 2012 at 11:33 PM

Yeah, this is pretty well known in the exercise community. Antioxidents blunt the hormetic stressor that exercise provides so you actually don't get the benefits from the exercise. Even ibuprofin PWO will limit the benefit you get from the workout.

F4d991ae6bcc8c23851369ad86fbef7d
2407 · November 07, 2012 at 6:00 AM

Without INSULIN (not insult, lol)

F4d991ae6bcc8c23851369ad86fbef7d
2407 · November 07, 2012 at 5:59 AM

Do antioxidants stop the non-insulin mediated glucose uptake process which is stimulated by training? (GLUT is mobilized to the surface of muscle cells to take sugar in without insulin to stimulate the process) ??

510bdda8988ed0d4b0ec0b738b4edb73
20908 · November 07, 2012 at 4:12 PM

I would inagine there no/little effect. The hormetic stress of exercise is the oxidative damage that results from all of the free radicals created during combustion. That's what the antioxidants undo.

Cf08ad26759fdd206a2c9f9385080a57
1005 · April 03, 2014 at 5:50 AM

You generally want a diet high in antioxidants if you exercise regularly. You'll still get the same benefits (possibly with greater performance metrics) with less damage to your body, so you can get up and do it again the next day.

3846a3b61bc9051e4baebdef62e58c52
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18635 · September 11, 2012 at 7:53 PM

Very interesting. I think this "I???m sure that there are further insights (and corrections) that can be extracted from the literature in place today, and I look forward to seeing that literature itself become half-obsolete next year." says it all though. For the time being I will stick to vitamin D and magnesium as my only supplements.

The problem with vitamin C at night is that ....well that is exactly when you are fasting. If you wanted to time it, it would seem taking it with your meals only is your best bet.

6120c989fd5b69f42a0834b69b87955b
24538 · September 25, 2012 at 9:42 PM

Hey, so my German host father wasn't just being a controlling weirdo when he chastised me for eating my St. Nicolas Day mandarin orange as a late night snack, and suggested I save it for morning.

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1005 · April 03, 2014 at 5:58 AM

http://www.ncbi.nlm.nih.gov/pubmed/21325105

"Our results indicate that administration of antioxidants during strenuous endurance training has no effect on the training-induced increase in insulin sensitivity in healthy individuals."

The half life for supplemental vitamin c may be a short as 30 minutes.

I like the idea of taking it at night or after exercise to reduce cortisol, but anytime is a good time for vitamin c (unless you have the genetic mutations to store a ton of iron.)

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