most recent 30 from http://paleohacks.com 2013-05-19T12:06:11Z http://paleohacks.com/feeds/question/147576 http://www.creativecommons.org/licenses/by-nc/2.5/rdf http://paleohacks.com/questions/147576/confused-help-on-apoe-genotype-and-paleo tye 2012-09-06T17:30:25Z 2012-11-22T17:11:42Z

<p>Just got my results from 23andme and I'm both epsilon2 (at rs429358) and epsilon4 (rs7412). While it does shed some light on my atypical response to paleo (improved HDL and trigs, but drastically increased LDLs, including some of the bad stuff).</p> <p>My question is: so what now?</p> <p>I'm starting not to be concerned with LDL as long as my HDL and trigs are good, especially with exercise and if I can keep lower-carb. But my docs freak out at 300+ LDLs even with a great trig/HDL ratio.</p> <p>Can anyone point me to some good journal articles or other advice and info for my e2/e4 ApoE type? I found lots on E2, E3, and E4, but most specifically leave out e2/e4's like me and results are contradictory.</p>

http://paleohacks.com/questions/147576/confused-help-on-apoe-genotype-and-paleo/148857#148857 Laura 2012-09-12T15:52:33Z 2012-09-12T15:52:33Z

<p>Did your doctor order the Apo E genotype or did you do it on your own? Do you know what your LDL-p is? My husband also had kick ass trig (35) and hdl (76) but high ldl(192) and very high ldl-p 1720.</p> <p>I am wondering if fat is a problem with him.</p>

http://paleohacks.com/questions/147576/confused-help-on-apoe-genotype-and-paleo/163602#163602 surfin' on a rocket 2012-11-22T14:28:32Z 2012-11-22T14:28:32Z

<p>Sounds like you could be more sensitive to a high fat diet because your genetics are suited to a diet low in saturated fat. Another way of saying it is that your genetics help you retain fat which means you don't need as much. Suggest you consider a more plant based diet. </p>

http://paleohacks.com/questions/147576/confused-help-on-apoe-genotype-and-paleo/163623#163623 Sataran 2012-11-22T17:11:42Z 2012-11-22T17:11:42Z

<p>E2/E4 is only 1 percent of the population. First, I'd make sure I'm E2/E4. Lots of people think they're E2/E4 but turn out to be E3/E3. If your E2 is TT and E4 is CC, then you're TC or E3/E3. Go to Disease Risk and find Alzheimer Disease, then click on Technical Report. If you're E2/E4 there, then you're right. It is rare. Most people who're ApoE4 tend to be E3/E4, about 20% of the population.</p>