most recent 30 from http://paleohacks.com 2013-06-20T03:40:01Z http://paleohacks.com/feeds/question/67561 http://www.creativecommons.org/licenses/by-nc/2.5/rdf http://paleohacks.com/questions/67561/vlc-and-physiological-insulin-resistance-and-impact-on-brain Alexandra 2011-09-28T04:23:17Z 2011-09-28T13:20:45Z

<p>If vlc/ketogenic diets can cause physiological insulin resistance - then why are such diets helpful for Alzheimer's? My endo calls Alzheimer's insulin resistance of the brain. Don't know if he's correct but if he is -- wouldn't the physiological insulin resistance experienced by vlc/ketogenic dieters have to potential to create/worsen insulin resistance in the brain? I've been eating coconut oil for years for weight loss maintenance,energy and also to protect the brain as I thought the ketones coconut oil help generate were good for the brain. Thoughts? </p>

http://paleohacks.com/questions/67561/vlc-and-physiological-insulin-resistance-and-impact-on-brain/67564#67564 Primordial 2011-09-28T06:27:49Z 2011-09-28T06:27:49Z

<p>Ketogenic Diets change the energy supply from glucose to ketones in most part of the brain. Since in Alzheimer's often the cells are insulin resistant and cannot metabolize glucose, changing the fuel gives them the ability to get energy again. If you are on ketones, it doesn't matter if you're insulin resistant, afaik.</p>

http://paleohacks.com/questions/67561/vlc-and-physiological-insulin-resistance-and-impact-on-brain/67585#67585 Alexandra 2011-09-28T13:20:45Z 2011-09-28T13:20:45Z

<p>Hi Greyman -- do a search on paleohacks (it's been discussed before) - I don't want to rehash. The physiological insulin resistance within the context of a very high fat, very low carb diet and normal blood glucose levels is an adaptation to the diet -- not the insulin resistance seen in overweight type 2s with high blood glucose. Ex: If you eat an apple after VLC for a long time -- your blood sugar will elevate higher and stay elevated longer than it would if you had been eating a high carb diet. Ugh -- I'm rehashing. My question was does this adaptive response affect the brain negatively but I think Primordial answered my question. Sorry if it sounded like I was criticizing vlc -- I wasn't --it's how I've eaten for years with no desire to change. There's Alzheimer's in my family so I wondered if the adaptive insulin resistance from vlc could negatively impact the brain. Just wondering.</p>