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by 0 · June 30, 2014 at 10:08 PM

i know dave asprey is not paleo & that supplements are a big thing over at bulletproof exec,but would be interested on some feedback on their/his recs for folate and b12,the recs are "Dose: >5mg of methylcobalamin or hydroxycobalamin and... (more)

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Methodician 0 · June 30, 2014 at 4:32 AM

personally based on nutrient tracking I find that I get plenty (if not excessive) b12 from dietary sources on a paleo diet (sources like fish and beef). Getting enough folate is a little more variable.Given the various issues with synthetic folate... (more)

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by 952 · June 07, 2014 at 3:37 AM

What is the easiest way to figure out the minimal effective dose of supplementation and dietary change to adjust for the following genetics? It seems that I have minor defects, but nothing serious. All other things being equal, I would love to... (more)

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paleot 0 · June 06, 2014 at 9:19 PM

That looks like a great methylation panel to me. A66G is your only red mark, where that's a fairly mild mutation. A1298C is fairly mild as well, and you're hetero there. You could maybe eat some more seafood and veg (beets / spinach.) I would be... (more)

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by 568 · April 16, 2014 at 4:28 PM

I've hardly touched a bean in a couple years. I'm looking to reintroduce legumes to my diet for a number of reasons. A few: folate, soluble fiber, lower methionine protein source, clean carbs, etc... What are some of the most nutritious and... (more)

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glib 0 · April 15, 2014 at 9:49 PM

I will go along with that, specially if the green peas are fresh frozen. Chickpeas under any circumstances, and they soak for two days and give you a 1/4 inch spear after that. for lentils I prefer the dark green French lentils, soaked one day.... (more)

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by 568 · February 05, 2014 at 11:41 PM

What are some good sources of folate other than leafy greens? Best I can find so far is chicken liver (or duck or other foul). Nice, because I wanted a good excuse to opt for chicken liver over beef liver now and then. I love them both. I... (more)

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glib 0 · February 05, 2014 at 11:05 PM

gasoline? acetone? let us all remember that cow spleen is an acquired taste too.

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by 0 · February 07, 2014 at 5:07 PM

So I just started taking folinic acid (it's called "megafolinic" by Source Naturals - 800 Mcg), but have experienced dizziness shortly after taking the pills in isolation. There could be a variety of causes for this, but I am wondering whether... (more)

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Erika_2 0 · February 07, 2014 at 5:07 PM

I relate to Matt 11 so much. I will feel horrible if I don't eat a meal with certain supplements, so just to be sure, I always take my supplements (UNLESS otherwise stated on the bottle) during/right after a meal. Also, you should NOT be... (more)

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by 0 · January 12, 2014 at 11:09 PM

So while many sites simply say folate is water-soluble and thus can't be stored by the body, I've seen a few sources, such as the wikipedia article on folate (http://en.wikipedia.org/wiki/Folic_acid) state that the body can store huge amounts... (more)

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by 568 · December 20, 2013 at 11:07 PM

I'm doing much better now while limiting my fiber intake. It's weird - fiber binds me up apparently. I try to keep it well below 30 grams, usually under 20 if I can but that's hard. The problem is that I'm also limiting my leafy greens - a major... (more)

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daz 0 · December 17, 2013 at 9:29 PM

you probably use this tool already, but just in case... you can use the nutrient-search-tool-here to define particular nutrient searches, ie. highest and lowest in certain 'things' such as fiber, potassium, folate in any combination you... (more)

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by 0 · November 18, 2013 at 6:11 PM

Does anyone know what the latest is on prenatal folate/folic acid supplementation? I was researching the topic on this site but it seems like the answer is still up in the air. I read the article by Chris Masterjohn but since then I have read... (more)

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somestranger 0 · November 18, 2013 at 6:11 PM

You have it backwards. People with an MTHFR gene defect (around 50% of the population has at least one mutation) convert folic acid to methyfolate slower than normal. The reason for this is that there are I believe 4 steps to conovert folic... (more)

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by 0 · October 11, 2013 at 6:06 PM

This may be a bit of a long post. Apologies in advance: I wanted to just get it out there. I began taking B12 (methylcobalamin) and folate (methylfolate), & ~2,500 IU D3/ 500mg K2 recently. While the symptoms & dramatic... (more)

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mareserinitatis 0 · October 11, 2013 at 6:06 PM

How much sodium are you getting? I found more sodium, less potassium really helps with the neurological issues I've had (especially tingling).

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by 992 · July 17, 2013 at 2:54 PM

While trying to further optimize my diet, I recently noticed that I have a homozygous C677T (TT genotype) MTHFR enzyme. Homozygous rs1801133(T;T) individuals have ~30% of the expected MTHFR enzyme activity, and rs1801133(C;T) heterozygotes... (more)

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Dragonfly 0 · July 17, 2013 at 2:54 PM

Liver is a great source of highly absorbable folate. And some folk eliminate their migraines with a vlc/ketogenic diet. YMMV.

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by 35 · May 02, 2013 at 11:54 AM

I have anemic tendencies and digestion issues (mainly bloating, but also incomplete elimination). Part of this is genetic, due to folate and B12 metabolism issues (I'm compound heterozygous for MTHFR, and I have a variant in the TCN2 gene that... (more)

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VB 0 · May 02, 2013 at 10:40 AM

Again, I will repeat myself - I do not believe in all that inflammation theory. I mean, I believe in inflammation, it is just works differently in my understanding. I bet it has something to do with gut flora. The only way we get... (more)

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by 1637 · September 07, 2013 at 2:12 PM

Hey y'all! So, here is the thing: About 7-8 months ago I started having tingling extremities. It got to the point where my hands and feet were constantly tingling and kind of numb. I had my regular GP at the time run a B12 serum test which was... (more)

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Andrealyne 0 · September 07, 2013 at 2:12 PM

I have similar symptoms. Neuro work up is negative. Will see neuro surgeon because I have alot of cervical myelopathy. My B12 is high and I don't supplement. I am homozygous MTHFR c766t- with other weird methylation issues. I also did a... (more)

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by 20 · November 03, 2012 at 2:01 AM

Hi, After suffering with severe stomach pain and recently having blood tests my girlfriend has tentatively been diagnosed with 'pernicious anemia', her results showed B12 & folate deficiency along with 'abnormally large' red blood cells.... (more)

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margarets 0 · November 03, 2012 at 12:01 AM

This is a complex issue. Your gf should follow her doctor's advice. Introducing a new diet at this stage will only complicate the diagnosis, because it introduces new variables. Also, some of what you've posted doesn't quite add up. Your gf... (more)

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by 40 · October 10, 2012 at 5:17 AM

So I eat a serving of white rice regularly as my carb to at least a few meals per week. My other carb sources are basically potatoes and squash. I know that white rice is enriched with vitamins (unless organic). My diet, on average, includes 7-12... (more)

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Alec_2 0 · October 10, 2012 at 5:17 AM

Forget the enriched rice, buy organic (it is cheap in bulk and stores well). I imagine your rice is enriched with folic acid and not folate. A number of threads on this site characterize the difference. I cook my rice in trotter stock, similar... (more)

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by 2198 · September 15, 2012 at 10:41 PM

Folic acid supplementation assists cell division. In cancer and healthy cells. Same thing for methyl folate supplements?  http://nutritiondiva.quickanddirtytips.com/folic-acid-and-cancer-risk.aspx (more)

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Tyler_F 0 · September 15, 2012 at 8:06 PM

http://chriskresser.com/folate-vs-folic-acid

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by 7490 · April 09, 2013 at 1:26 PM

I've seen a few questions and answers touch on this, but I'm curious: Has anyone been treated for hetero- or homozygous methylenetetrahydrofolate reductase (MTHFR, aka "Motherf***er) enzyme deficiency? If so, what symptoms were you having... (more)

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thegiantess 0 · April 09, 2013 at 1:26 PM

Okay, so this is an old thread, but hopefully someone will get the notification and help a girl out! I hear all this talk about the MTHFR SNP that is found on 23andME, but where is it? I have been staring at my 23andME results and I can't seem to... (more)

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by 0 · July 31, 2012 at 7:30 PM

I am a 35 Chinese female and have been doing Crossfit for a year. I started on a strict paleo diet four months ago and modify paleo eight months before that. I also take a multi-vitamin from Pure Encapsulations call Nutrient 950 with vitamin K. ... (more)

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Laurie_D_ 0 · July 31, 2012 at 5:50 PM

Have you been checked for the MTHFR gene? http://www.ncbi.nlm.nih.gov/pubmed/17024648 It can be associated with low hemoglobin levels.

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by 596 · October 03, 2012 at 3:22 AM

Hi folks, I'm currently finishing my multivitamin(which is a pretty good formula, from an European bulk store, is a 4 capsule dose, with pretty good forms of ingredients and low folic acid, an i can control the dosage, i may add just one capsule)... (more)

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Lynn_6 0 · July 10, 2012 at 5:17 PM

I like B-Complex Plus by Pure Encapsulations. You could also try calling NEEDS and speaking with someone who could recommend one based on you particular needs/desires. I've found them to be very helpful. http://www.needs.com/ (more)

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by 309 · May 16, 2012 at 2:56 PM

So I'm a little overwhelmed at all the info regarding pre-conception/prental supplementations. I would like to start taking fermented Cod Liver Oil, but what else? A folate & iron supplement? I feel like even a whole foods vitamin could be... (more)

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Dragonfly 0 · May 15, 2012 at 11:46 PM

The RDA is not sufficient--it's just enough to prevent disease for some people--and definitely not enough for optimum health for ttc or growing a baby. I don't recommend CLO to my clients, unless they can't eat liver or dairy. The ratio of A to... (more)

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by 606 · May 31, 2012 at 2:25 AM

What were your experiences? Would you recommend keeping your diet on the low, so as to avoid arguments with medical staff? Would you ever mention that you eat liver or take cod liver oil (given the fear of Vitamin A), or mention that you're... (more)

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DanielleO812 0 · May 10, 2012 at 12:49 PM

Can I ask you where you are (plan on) getting your folate from? As in which foods?

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by 1449 · October 21, 2011 at 9:24 AM

I recently found out (from 23andme) that I am heterogeneous (one copy of the "bad" gene) for the MTHFR C677T polymorphism. This means that my body has reduced ability to convert folate into the active form of folate (5-methyltetrahydrafolate).... (more)

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Gazelle 0 · October 20, 2011 at 9:52 PM

When I got pregnant my doctor discovered I have this "bad gene" too (also confirmed by 23andme) and prescribed Folapro which contains Metafolin, an active form of folate called L-5-methyl tetrahydrofolate. My homocysteine level is around 5 though... (more)

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by 2791 · October 20, 2011 at 5:29 PM

I have read in several places that it is best to avoid Folic Acid supplementation because it is not a natural form of Folate and has been correlated to negative outcomes in some studies. Some multivitamins have started using alternatives likes... (more)

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cliff_1 0 · October 20, 2011 at 2:38 PM

avoid because its not found in food. Chris masterjohn and chris kesser have both covered this issue.

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by 390 · February 18, 2014 at 11:57 PM

I'm a man and I have 12.3 hemoglobin. My blood tests say Iron, B12 and Folate (B9) are alright. My Hematocrits are low, and Ferritin high. What gives?

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stldrmn 0 · February 18, 2014 at 11:57 PM

Seeing as this is a really old post I hope you've already figured out/corrected whatever was causing the anemia, but I still wanted to post this in case anyone else stumbles across it like I did. I've been struggling with a somewhat similar... (more)

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by 3428 · January 25, 2013 at 6:18 PM

Folate (vitamin B9) promotes cardiovascular health and is needed for several cellular functions. Some natural sources of folate include grains and legumes, definitely non-paleo. I know liver has a good amount of folate but I happen to hate liver... (more)

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electronicsDude 0 · January 25, 2013 at 6:18 PM

Check out the whfoods site on folate: http://www.whfoods.com/genpage.php?tname=nutrient&dbid=63 At the top they only list greens and beans, but on the bottom they list many more foods, many of which have 10-20% of the DV for folate, including... (more)

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by 1246 · April 25, 2010 at 12:35 AM

Clearly ancient women were not popping folic acid pills in anticipation of a deformity-free child. I would also expect that spina bifida is a disease of civilization. If it was an ancient disease, I think the mother's body would miscarry it... (more)

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Jay_5 0 · April 24, 2010 at 3:54 PM

I wouldn't take more than occasional folic acid unless I was pregnant.