Folate

Folate

Folate Questions

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by -1 · about 11 hours ago

i know dave asprey is not paleo & that supplements are a big thing over at bulletproof exec,but would be interested on some feedback on their/his recs for folate and b12,the recs are "Dose: >5mg of methylcobalamin or hydroxycobalamin and... (more)

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Methodician 0 · June 30, 2014 at 4:32 AM

personally based on nutrient tracking I find that I get plenty (if not excessive) b12 from dietary sources on a paleo diet (sources like fish and beef). Getting enough folate is a little more variable.Given the various issues with synthetic folate... (more)

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by 598 · about 11 hours ago

I've hardly touched a bean in a couple years. I'm looking to reintroduce legumes to my diet for a number of reasons. A few: folate, soluble fiber, lower methionine protein source, clean carbs, etc... What are some of the most nutritious and... (more)

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glib 0 · April 15, 2014 at 9:49 PM

I will go along with that, specially if the green peas are fresh frozen. Chickpeas under any circumstances, and they soak for two days and give you a 1/4 inch spear after that. for lentils I prefer the dark green French lentils, soaked one day.... (more)

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by 0 · about 11 hours ago

So I just started taking folinic acid (it's called "megafolinic" by Source Naturals - 800 Mcg), but have experienced dizziness shortly after taking the pills in isolation. There could be a variety of causes for this, but I am wondering whether... (more)

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Erika_2 0 · February 07, 2014 at 5:07 PM

I relate to Matt 11 so much. I will feel horrible if I don't eat a meal with certain supplements, so just to be sure, I always take my supplements (UNLESS otherwise stated on the bottle) during/right after a meal. Also, you should NOT be... (more)

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by 0 · about 11 hours ago

This may be a bit of a long post. Apologies in advance: I wanted to just get it out there. I began taking B12 (methylcobalamin) and folate (methylfolate), & ~2,500 IU D3/ 500mg K2 recently. While the symptoms & dramatic... (more)

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mareserinitatis 0 · October 11, 2013 at 6:06 PM

How much sodium are you getting? I found more sodium, less potassium really helps with the neurological issues I've had (especially tingling).

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by 1005 · about 12 hours ago

While trying to further optimize my diet, I recently noticed that I have a homozygous C677T (TT genotype) MTHFR enzyme. Homozygous rs1801133(T;T) individuals have ~30% of the expected MTHFR enzyme activity, and rs1801133(C;T) heterozygotes... (more)

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Michael_17 0 · July 17, 2013 at 5:11 AM

Great question. ATM I can't really answer that well other than to suggest that if homocysteine levels are not suspiciously high then folate supplementation may not be necessary (as the gene may not be expressed if methylcation cycle is functioning... (more)

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by 20 · about 12 hours ago

Hi, After suffering with severe stomach pain and recently having blood tests my girlfriend has tentatively been diagnosed with 'pernicious anemia', her results showed B12 & folate deficiency along with 'abnormally large' red blood cells.... (more)

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syrahna 0 · November 03, 2012 at 2:01 AM

All I can say is, as someone who takes TWO B-12 shots a month and has for over three years, TELL HER TO ENJOY THE HECK OUT OF THE B-12 and then worry about her diet. The whole point of PA is that she isn't going to get that vitamin any other way... (more)

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by 2199 · about 12 hours ago

Folic acid supplementation assists cell division. In cancer and healthy cells. Same thing for methyl folate supplements??? http://nutritiondiva.quickanddirtytips.com/folic-acid-and-cancer-risk.aspx (more)

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Matt_11 0 · September 15, 2012 at 10:41 PM

Many cancer cells express an increased number of folate receptors. This observation is actually used to treat some cancers, see Folate Targeting.

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by 7660 · about 12 hours ago

I've seen a few questions and answers touch on this, but I'm curious: Has anyone been treated for hetero- or homozygous methylenetetrahydrofolate reductase (MTHFR, aka "Motherf***er) enzyme deficiency? If so, what symptoms were you having... (more)

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Sara_S_ 0 · August 06, 2012 at 11:19 PM

I love that you call it the Motherf***er enzyme, too. When I talk about it, that's always what I say. Because it really is a mother f*er. I found out that I'm hetero for the C677T mutation with a 23andme analysis. I started supplementing with... (more)

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by 596 · about 12 hours ago

Hi folks, I'm currently finishing my multivitamin(which is a pretty good formula, from an European bulk store, is a 4 capsule dose, with pretty good forms of ingredients and low folic acid, an i can control the dosage, i may add just one capsule)... (more)

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laura_29 0 · September 19, 2012 at 3:09 AM

I use NOW brand B complex. I am very pleased with it. It's affordable and it works as it should.

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by 309 · about 12 hours ago

So I'm a little overwhelmed at all the info regarding pre-conception/prental supplementations. I would like to start taking fermented Cod Liver Oil, but what else? A folate & iron supplement? I feel like even a whole foods vitamin could be... (more)

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Dragonfly 0 · May 15, 2012 at 11:46 PM

The RDA is not sufficient--it's just enough to prevent disease for some people--and definitely not enough for optimum health for ttc or growing a baby. I don't recommend CLO to my clients, unless they can't eat liver or dairy. The ratio of A to... (more)

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by 605 · about 12 hours ago

What were your experiences? Would you recommend keeping your diet on the low, so as to avoid arguments with medical staff? Would you ever mention that you eat liver or take cod liver oil (given the fear of Vitamin A), or mention that you're... (more)

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Gazelle 0 · May 10, 2012 at 5:32 AM

I nodded and smiled with my midwife a bit. I think I mentioned that I avoided gluten, sugar and "junk" which was fine with her! She trusted me when I told her I was taking a "prenatal", though I didn't mention it didn't contain DHA and I was... (more)

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by 390 · about 13 hours ago

I'm a man and I have 12.3 hemoglobin. My blood tests say Iron, B12 and Folate (B9) are alright. My Hematocrits are low, and Ferritin high. What gives?

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Tom_R_ 0 · August 16, 2011 at 5:58 PM

I've posted several times on here regarding my unexplained anemia (35 year old male). My hemoglobin is also about 12.3. At times, my iron and ferritan levels have been low but are currently fine. B12 is fine. My WBC and RBC counts are slightly... (more)

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by 1276 · about 13 hours ago

Clearly ancient women were not popping folic acid pills in anticipation of a deformity-free child. I would also expect that spina bifida is a disease of civilization. If it was an ancient disease, I think the mother's body would miscarry it... (more)

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Matt_1 0 · April 23, 2010 at 8:56 PM

Okay I will try to answer this. Spina bifida occurs in all parts of the world at varying levels. Evidence shows that it has always happened throughout human history. Hunter-gatherers babies suffered just as people do now however it may have been... (more)

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by 0 · October 23, 2014 at 4:18 AM

So while many sites simply say folate is water-soluble and thus can't be stored by the body, I've seen a few sources, such as the wikipedia article on folate (http://en.wikipedia.org/wiki/Folic_acid) state that the body can store huge amounts... (more)

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by 598 · October 23, 2014 at 4:17 AM

I'm doing much better now while limiting my fiber intake. It's weird - fiber binds me up apparently. I try to keep it well below 30 grams, usually under 20 if I can but that's hard. The problem is that I'm also limiting my leafy greens - a major... (more)

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daz 0 · December 17, 2013 at 9:29 PM

you probably use this tool already, but just in case... you can use the nutrient-search-tool-here to define particular nutrient searches, ie. highest and lowest in certain 'things' such as fiber, potassium, folate in any combination you... (more)

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by 1649 · October 23, 2014 at 4:05 AM

Hey y'all! So, here is the thing: About 7-8 months ago I started having tingling extremities. It got to the point where my hands and feet were constantly tingling and kind of numb. I had my regular GP at the time run a B12 serum test which was... (more)

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Andrealyne 0 · September 07, 2013 at 2:12 PM

I have similar symptoms. Neuro work up is negative. Will see neuro surgeon because I have alot of cervical myelopathy. My B12 is high and I don't supplement. I am homozygous MTHFR c766t- with other weird methylation issues. I also did a... (more)

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by 40 · October 23, 2014 at 3:52 AM

So I eat a serving of white rice regularly as my carb to at least a few meals per week. My other carb sources are basically potatoes and squash. I know that white rice is enriched with vitamins (unless organic). My diet, on average, includes 7-12... (more)

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Alec_2 0 · October 10, 2012 at 5:17 AM

Forget the enriched rice, buy organic (it is cheap in bulk and stores well). I imagine your rice is enriched with folic acid and not folate. A number of threads on this site characterize the difference. I cook my rice in trotter stock, similar... (more)

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by 1436 · October 23, 2014 at 3:23 AM

I recently found out (from 23andme) that I am heterogeneous (one copy of the "bad" gene) for the MTHFR C677T polymorphism. This means that my body has reduced ability to convert folate into the active form of folate (5-methyltetrahydrafolate).... (more)

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esque 0 · October 21, 2011 at 9:24 AM

I discovered I had this gene (hetero like you) on 23andme and started taking the active folate. Then I had a blood test and my folate was absurdly high. I have sinced eased off on the supplementation as in spite of my wack gene, I seem to be... (more)

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by 598 · October 22, 2014 at 4:13 AM

What are some good sources of folate other than leafy greens? Best I can find so far is chicken liver (or duck or other foul). Nice, because I wanted a good excuse to opt for chicken liver over beef liver now and then. I love them both. I... (more)

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glib 0 · February 05, 2014 at 11:05 PM

gasoline? acetone? let us all remember that cow spleen is an acquired taste too.

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by 0 · October 22, 2014 at 3:45 AM

I am a 35 Chinese female and have been doing Crossfit for a year. I started on a strict paleo diet four months ago and modify paleo eight months before that. I also take a multi-vitamin from Pure Encapsulations call Nutrient 950 with vitamin K. ... (more)

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Laurie_D_ 0 · July 31, 2012 at 5:50 PM

Have you been checked for the MTHFR gene? http://www.ncbi.nlm.nih.gov/pubmed/17024648 It can be associated with low hemoglobin levels.

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by 3509 · October 22, 2014 at 3:14 AM

Folate (vitamin B9) promotes cardiovascular health and is needed for several cellular functions. Some natural sources of folate include grains and legumes, definitely non-paleo. I know liver has a good amount of folate but I happen to hate liver... (more)

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Eugenia 0 · May 12, 2012 at 6:40 PM

If you're not trying to lose weight, then ferment lentils (also high on iron and manganese). While lentils are legumes and are not allowed on Paleo because of their lectins, research has shown that just like with soy, when properly fermented, most... (more)

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by 0 · October 20, 2014 at 4:04 AM

Does anyone know what the latest is on prenatal folate/folic acid supplementation? I was researching the topic on this site but it seems like the answer is still up in the air. I read the article by Chris Masterjohn but since then I have read... (more)

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somestranger 0 · November 18, 2013 at 6:11 PM

You have it backwards. People with an MTHFR gene defect (around 50% of the population has at least one mutation) convert folic acid to methyfolate slower than normal. The reason for this is that there are I believe 4 steps to conovert folic... (more)

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by 30 · October 20, 2014 at 3:57 AM

I have anemic tendencies and digestion issues (mainly bloating, but also incomplete elimination). Part of this is genetic, due to folate and B12 metabolism issues (I'm compound heterozygous for MTHFR, and I have a variant in the TCN2 gene that... (more)

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Lazza 0 · May 02, 2013 at 11:54 AM

If you had a colonic biopsy showing inflammation then it seems likely you have an inflammatory bowel disease (Crohn's, ulcerative colitis). Like most autoimmune diseases, folks with IBD can experience periods of remission and relapse. So it... (more)

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by 952 · October 18, 2014 at 4:16 AM

What is the easiest way to figure out the minimal effective dose of supplementation and dietary change to adjust for the following genetics? It seems that I have minor defects, but nothing serious. All other things being equal, I would love to... (more)

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paleot 0 · June 06, 2014 at 9:19 PM

That looks like a great methylation panel to me. A66G is your only red mark, where that's a fairly mild mutation. A1298C is fairly mild as well, and you're hetero there. You could maybe eat some more seafood and veg (beets / spinach.) I would be... (more)

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by 2861 · October 18, 2014 at 3:22 AM

I have read in several places that it is best to avoid Folic Acid supplementation because it is not a natural form of Folate and has been correlated to negative outcomes in some studies. Some multivitamins have started using alternatives likes... (more)

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Dragonfly 0 · October 20, 2011 at 5:29 PM

Sorry, not an answer, but I couldn't fit it all in the comments. This is really interesting. I appreciate you bringing it up, Paleo2.0! As a Pregnancy coach, I really need to know about this topic. So here we have some folks (the ones you... (more)

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