Genetics

Genetics

Genetics Questions

B121fdbc1aaa6130f5bda3bf84e3ba2d
0
Votes
0
Answers
0
Views
603
by 952 · about 8 hours ago

Did you anyone took specific actions based on microbiome sequencing?

47a42b6be94caf700fce9509e38bb6a4
8
Votes
8
Answers
11
Views
2K
by 9647 · about 8 hours ago

Just the question as it stands, really. Is anyone out there familiar enough with this academic community to know if the diet has taken on? And when I say anthropologists I mean the scientific kind (physical anthropology, etc.), not the ones who... (more)

93f44e8673d3ea2294cce085ebc96e13
Patrik 0 · October 09, 2010 at 10:59 PM

This is gonna be a fun one. Gonna approach in a pretty similar manner to Matthew. Full disclosure: I hold a BA in Physical Anthropology from university that houses some of the "rock-stars" of evolutionary psychology (a branch of physical... (more)

B121fdbc1aaa6130f5bda3bf84e3ba2d
0
Votes
0
Answers
3
Views
489
by 952 · about 9 hours ago

What is the easiest way to figure out the minimal effective dose of supplementation and dietary change to adjust for the following genetics? It seems that I have minor defects, but nothing serious. All other things being equal, I would love to... (more)

best answer

Cf08ad26759fdd206a2c9f9385080a57
paleot 0 · June 06, 2014 at 9:19 PM

That looks like a great methylation panel to me. A66G is your only red mark, where that's a fairly mild mutation. A1298C is fairly mild as well, and you're hetero there. You could maybe eat some more seafood and veg (beets / spinach.) I would be... (more)

Bcb2f5436d11467e89123680c046b858
1
Votes
1
Answers
4
Views
654
by 1336 · about 9 hours ago

I've been researching celiac disease a ton over the past few days since getting my 23andme results back. It's a very confusing tangle of genes, but it looks like I'm heterozygous for the "celiac genes", both HLA-DQ2 (2.5, but not 2.2) and HLA-DQ8.... (more)

7841848bd0c27c64353c583fb7971242
Sara_S_ 0 · July 06, 2013 at 8:08 PM

Do you have any relatives with celiac disease? I personally think it's a good idea to get tested before going gluten free, as many people are asymptomatic. I think most doctors aren't keen to test you unless you either have symptoms of celiac... (more)

3fc95bca9e723edfbbb72b172798ab49
0
Votes
0
Answers
2
Views
967
by 1346 · about 9 hours ago

We are our genes, but our genes are not our fate. As a paleo community we tend to concern ourselves greatly with our natural heritage, our predispositions and our gene expressions. We are very interested in bringing out the best of what we are and... (more)

26b7615ef542394102785a67a2786867
animalcule 0 · March 15, 2013 at 6:05 AM

Most things about the way any modern human looks are a mixture of genetics, epigenetics, and environment/nurture/'the kitchen'. This is certainly true of that particular anatomical feature. I'm not muscular (thin), don't have crazy low body fat,... (more)

7dab2d8c97e44d8d0c298e5c9d5d75bc
1
Votes
1
Answers
2
Views
1.3K
by 631 · about 9 hours ago

Hey all, I need to do a genetics paper, and it's pretty free reign. This is the assignment: The Final Project A term paper is required. The term paper is due when you turn in your final assignment. Please submit the paper as a Microsoft Word... (more)

E35e3d76547b18096a59c90029e7e107
David_Moss 0 · January 19, 2013 at 9:34 PM

How substantial the alteration of our genetics has been since the neolithic? I don't know whether that meets the remit or is too macro an issue. Consider this summary of the debate on wikipedia: According to Alexander Str??hle, Maike ... (more)

Bee4e0fda817da9857443bd40f552a75
1
Votes
1
Answers
5
Views
1.2K
by 240 · about 9 hours ago

I just wonder why it happens?

Ed7403e397077dd1acdbf25c7f6e56ce
Kashkillz 0 · December 06, 2012 at 10:06 PM

Kettlebell... squats... lunges... plyometrics... You are not a victim!!!

4517f03b8a94fa57ed57ab60ab694b7d
4
Votes
4
Answers
6
Views
1.1K
by 213 · about 9 hours ago

Did you learn something that lead to a significant change in your daily routine? Do you think your health will be even better now that you have this new information? Do you trust the results? Do you think the science is too young to be... (more)

De267f213b375efca5da07890e5efc25
balor123 0 · November 30, 2012 at 9:50 PM

I used 23andme and Promethease as well. I was having some difficult to diagnose health problems and I thought that the genetic tests might help me narrow down other tests to pursue. People usually focus on the disease risk factors but it's worth... (more)

4517f03b8a94fa57ed57ab60ab694b7d
1
Votes
1
Answers
2
Views
509
by 213 · about 9 hours ago

Is this done through one's doctor, or is there a more accurate genetic testing method that one's doctor might not be aware of? Is there a lab out there that studies this particular genetic condition that also offers testing to the public? I am... (more)

79fc447191de75e7c178951594a43f13
JRM 0 · November 28, 2012 at 3:48 AM

23andme.com is probably cheaper than going to your doctor. I tested there and found out I don't carry the mutations.

D01e44fabc04e69a92e65e3179d81e06
6
Votes
6
Answers
7
Views
1.9K
by 72 · about 9 hours ago

My son (1.5yo) was just diagnosed with a very, very rare genetic disorder (Primary Hyperoxaluria Type III). The specialist who actually described this disease hypothesises that the genetic mutation causes the pathway for the proper breakdown of... (more)

32f5749fa6cf7adbeb0b0b031ba82b46
Matt_11 0 · July 28, 2012 at 12:24 PM

Not sure I understand how a vegan diet minimizes oxalates... which is the problem with hyperoxaluria. Oxalates are absent in animal products, and present in many plant foods. I'm guessing it stresses the kidneys so they're just trying to minimize... (more)

D13278772f6612432bf53413fad4e7af
6
Votes
6
Answers
7
Views
1.2K
by 801 · about 9 hours ago

As I understand the core argument for paleo, modern man retains what is essentially a 100,000-year old gene map, and many of our current health and psychological issues result from nutritional and behavioral departures from what Grok's genome was... (more)

best answer

81fca18329e68e227cdfef3857bfef96
Mark_26 0 · July 18, 2012 at 9:33 PM

I would agree with the second paragraph that human beings are no longer evolving due to natural selection. The moment humans began adapting the environment to suit their needs they no longer adapted themselves to the environment. Essentially,... (more)

9d43f6873107e17ca4d1a5055aa7a2ad
4
Votes
4
Answers
7
Views
1.1K
by 56616 · about 10 hours ago

I was talking with some relatives who have stomach problems and one thing I noticed is that a lot of them are on NSAIDs- ibuprofen and aspirin, for example. Over the years I have been on and off the paleo diet, but never gotten back to the point I... (more)

121a16aded2bed8dca492d3c9662ef4c
Stephen_5 0 · June 23, 2012 at 2:48 PM

You wrote: The GI bleeding must just be the tip of the iceberg, there much be other damage occurring before it comes to that. Actually, GI bleeds are probably the initial and biggest side effect of NSAIDs. It happens very quickly, it... (more)

E9c1630487f5a2b54898131e5c19e32f
0
Votes
0
Answers
2
Views
721
by 0 · about 10 hours ago

I'm being hopeful... This is a long shot and I'm pretty sure nobody will answer...but is there anyone with NF out there who is on paleo? Do you think that it will help with any of the symptoms? Thanks in advance.

E76821f1019f5284761bc4c33f2bf044
LaurenM 0 · April 15, 2012 at 9:54 AM

You have probably already found this, but the only lead I could find (hopefully more knowledgeable people can either discredit or use as a springboard) was here:... (more)

77ecc37f89dbe8f783179323916bd8e6
13
Votes
13
Answers
15
Views
4K
by 5002 · about 10 hours ago

I'll start with my question: Do you agree with Melissa McEwen's critique of Jack Kruse's (mis)use of evolutionary biology? I should note that I am a fan of both McEwen and Kruse. McEwen's blog post is... (more)

9d43f6873107e17ca4d1a5055aa7a2ad
Bread_Eating_Beelzebub 0 · April 02, 2012 at 3:34 AM

You have no idea how hard that post was to write. I mean, it's so hard to read Dr. Kruse's writing and find consistant threads in it. He has references on the bottom of some post, but mostly they do not correspond to things in his posts that I... (more)

78cb3c4f70de5db2adb52b6b9671894b
8
Votes
8
Answers
16
Views
1.8K
by 5509 · about 10 hours ago

I know that strict paleo doesn't include grains, dairy or legumes. However, I think the majority of people here are flexible with what they eat. Butter and cream seem to be sacred gods on this site. I was wondering if I could do some sort of poll... (more)

best answer

96bf58d8c6bd492dc5b8ae46203fe247
Nance 0 · March 28, 2012 at 12:20 AM

I'd have to say many of my reactions to food would be compatible with a hunting/gathering ancestry. I hope you get lots of diverse responses. Russian, Polish and Scottish are my dominant ancestries. Experimentation and use of probiotics has... (more)

5f6acaa2591c41cc091fffd6e453c518
1
Votes
1
Answers
5
Views
1.5K
by 203 · about 10 hours ago

Hi! Because of constipation, which is now better, my G.I specialist got me to take a blood test to see if I have celiac or not. The results were that I'm a carrier for Celiac disease but it came back negative. My aunt didnt develop properly... (more)

A2c38be4c54c91a15071f82f14cac0b3
Mscott 0 · March 24, 2012 at 3:07 AM

If you haven't been eating gluten leading up to the blood test the ability of the test to identify celiac disease drops considerably. I know someone who stopped eating gluten, felt much much better, then went to the doctor a few weeks later to be... (more)

59ee717de524f921efb7f2984157339f
4
Votes
4
Answers
10
Views
1.1K
by 871 · about 10 hours ago

I have a question that has been on my mind for a while now, and I am wondering what some other people think of this. So, having been strict Paleo for over a year now, that is my choice, I know that. my Significant other, is a wonderfully... (more)

Ccacf7567273244733bc991af4ac42ed
PrimalDanny 0 · February 22, 2012 at 12:09 AM

It may not be a helpful answer, but I'd really recommend trying to look beyond weight as the only measure of health. I'd also be cautious of drawing conclusions about what other people are eating or doing when you don't see them. I'm sure there... (more)

B121fdbc1aaa6130f5bda3bf84e3ba2d
10
Votes
10
Answers
9
Views
2.1K
by 952 · about 10 hours ago

Have you extracted any actionable, effective and yet counter-intuitive (to conventional wisdom and general paleo knowledge) conclusions from 23andme or other genetic testing companies?

Medium avatar
Dorado_Galore 0 · February 15, 2012 at 8:24 PM

You probably are not looking for grounds upon which to sue 23andme, but... The word "actionable" means "affording grounds for legal action" and "violating principles of justice." I get that you mean something closer to: "Based on one's genome,... (more)

E34fbfa1bca9ae970c9c7313bf9de9f8
3
Votes
3
Answers
2
Views
1.7K
by 1436 · about 10 hours ago

I recently found out (from 23andme) that I am heterogeneous (one copy of the "bad" gene) for the MTHFR C677T polymorphism. This means that my body has reduced ability to convert folate into the active form of folate (5-methyltetrahydrafolate).... (more)

Ee7c5b7b9d4cd48d61dc259e6966a725
esque 0 · October 21, 2011 at 9:24 AM

I discovered I had this gene (hetero like you) on 23andme and started taking the active folate. Then I had a blood test and my folate was absurdly high. I have sinced eased off on the supplementation as in spite of my wack gene, I seem to be... (more)

Af1d286f0fd5c3949f59b4edf4d892f5
8
Votes
8
Answers
9
Views
1.4K
by 18412 · about 10 hours ago

I have a large family. I have always been very influential in my family, especially with my brothers and sisters. I am also the most fit and perceived as the most "healthy" (it's very difficult for me to say that at the moment) amongst my... (more)

best answer

072fd69647b0e765bb4b11532569f16d
Tom_R_ 0 · September 15, 2011 at 5:44 PM

First, I would ask the question: do the pros of leading your siblings down the road you have gone (i.e. getting in shape and "ripped" with the resulting other effects) outweigh the cons (i.e. remaining overweight)? Put another way, is presuming... (more)

3f11b5fda91063846bba45daac3541bd
5
Votes
5
Answers
5
Views
3.9K
by 1186 · about 10 hours ago

Pyroluria-- Is it real? Is it permanent? Those that pay attention to it regard it as genetic, requiring permanent B6 supplementation. Nora Gedgaudas in "Primal Mind Primal Body" has a whole appendix on it and seems to share this view. Any... (more)

5b5b7efa9b3df6c2d80e43883e4957c1
Harry_3 0 · May 16, 2012 at 10:56 AM

Oh its real alright. I have Pyroluria, it took me 8 years to work out what caused all my symptoms, these symptoms included: Brain fog Poor concentration and memory Depression Anxiety Chronic fatigue (really adrenal fatigue) Digestive... (more)

93f44e8673d3ea2294cce085ebc96e13
6
Votes
6
Answers
5
Views
1.4K
by 10502 · about 10 hours ago

Just got my 23andme data back -- would love to know what is the best way to get the most actionable data out of it. What should I look at that will let me make a change in my diet, lifestyle, fitness today? Anything? (more)

9d43f6873107e17ca4d1a5055aa7a2ad
Bread_Eating_Beelzebub 0 · August 20, 2011 at 3:44 PM

Hand's down it's Promethease. You'll get a full report that will pick out interesting genes, like those related to folate, iron, and vitamin A.

77ecc37f89dbe8f783179323916bd8e6
26
Votes
26
Answers
84
Views
5.5K
by 5002 · about 10 hours ago

I've always wondered if the different levels in carb tolerance that we often see has anything to do with genetic differences that related to ethnicity. I, for example, am half Italian (mother born there) and half Jewish-Russian (perhaps Belarus;... (more)

095ef76482234d3db444b77d7ed01c29
Andy 0 · August 03, 2011 at 1:21 AM

Scotch/Irish and Seminole/Cherokee... very sensitive to carbs. I get fat easily if I eat too many, my blood sugar gets too high. Even when it comes to alcohol, I simply cannot tolerate it. 2 drinks and I'm done. But on the reservation, the... (more)

D30ff86ad2c1f3b43b99aed213bcf461
10
Votes
10
Answers
5
Views
1.2K
by 12174 · about 10 hours ago

Non-Africans Are Part Neanderthal, Genetic Research Shows http://www.sciencedaily.com/releases/2011/07/110718085329.htm In light of these findings, is there anything that we can extrapolate about the nutritional needs (such as macronutrient... (more)

0bc6cbb653cdc5e82400f6da920f11eb
Matt_1 0 · July 18, 2011 at 11:05 PM

Some non-African populations, sometimes mentioned here, with quite varying traditional diets include: Okinawans Chinese Kitavans Inuit Plains Indians Italians French Australian aborigines If all these populations are equally decended from... (more)

9d43f6873107e17ca4d1a5055aa7a2ad
16
Votes
16
Answers
9
Views
4.1K
by 56616 · about 10 hours ago

Chris and I were having a conversation about how some people do really awesome on pretty low carb and some people feel sick. I started getting curious about whether this might have something to do with "neanderthal ancestry." If you have DNA data... (more)

3aea514b680d01bfd7573d74517946a7
Rose 0 · July 18, 2011 at 8:08 PM

What a great little gadget! I just ran mine and got a score of 20. I've been thriving on a "zero-carb" diet for the last two years, and have found that vegetables -- with the exception of some nuts (walnuts, macadamias) and dark leafy greens (e.g.... (more)

Get Free Paleo Recipes