Loren Cordain argues (without a citation) that the human genome has chagned only .02 percent in 40,0000 years. But other sources say that because of population growth, human genetics has changed much more rapidly in the last 5,000 years than the... (more)
Just the question as it stands, really. Is anyone out there familiar enough with this academic community to know if the diet has taken on? And when I say anthropologists I mean the scientific kind (physical anthropology, etc.), not the ones who... (more)
I've been researching celiac disease a ton over the past few days since getting my 23andme results back. It's a very confusing tangle of genes, but it looks like I'm heterozygous for the "celiac genes", both HLA-DQ2 (2.5, but not 2.2) and HLA-DQ8.... (more)
Hi, I have recently taken Genova's DetoxiGenomic Profile. Apparently I am absent of the GSTM! Glutathione gene. If glutathione supplementation is useless, what would you recommend I do? Regards, Neil.
Dear all! What do you think about creating the ultimate hacking thread for Apo-??4/??4 gene mutations to discuss practical real-life implications. What worked and what did not for cholesterol numbers and overall well-being in terms of lifestyle,... (more)
Hey all, I need to do a genetics paper, and it's pretty free reign. This is the assignment: The Final Project A term paper is required. The term paper is due when you turn in your final assignment. Please submit the paper as a Microsoft Word... (more)
I thought this might be of interest to some of the folks on here. It is a free online course offered by Duke University called "Introduction to Genetics and Evolution". https://www.coursera.org/course/geneticsevolution (more)
Thanks for sharing, I will definitely sign up. Also check out http://evolvify.com/ I just found it and it's about physchology and evolution in relation to a paleo lifestyle/diet.
Did you learn something that lead to a significant change in your daily routine? Do you think your health will be even better now that you have this new information? Do you trust the results? Do you think the science is too young to be... (more)
Is this done through one's doctor, or is there a more accurate genetic testing method that one's doctor might not be aware of? Is there a lab out there that studies this particular genetic condition that also offers testing to the public? I am... (more)
Since a good part of the paleo rationale is based on the idea that we are not genetically adapted to eat a certain way, it seems very relevant and quite interesting to look at this example of how quickly such a genetic mutation/adaptation can... (more)
Since there is talk about gaining weight all over paleo hacks, i was wondering when played defensive end in high school when i weighed 240 (im 190 now) i was benching 325 for reps, powercleaning 260 for reps, and deadlifting 450-480 pounds, this... (more)
As I understand the core argument for paleo, modern man retains what is essentially a 100,000-year old gene map, and many of our current health and psychological issues result from nutritional and behavioral departures from what Grok's genome was... (more)
I was talking with some relatives who have stomach problems and one thing I noticed is that a lot of them are on NSAIDs- ibuprofen and aspirin, for example. Over the years I have been on and off the paleo diet, but never gotten back to the point I... (more)
When we observe the diets of primitive tribes currently still in or close to the stone age, we see that they vary quite a bit. For example, the Kitava Island folks eat a lot of carbs (by our "paleo" standards), and the Inuit-like folks in north... (more)
I'll start with my question: Do you agree with Melissa McEwen's critique of Jack Kruse's (mis)use of evolutionary biology? I should note that I am a fan of both McEwen and Kruse. McEwen's blog post is... (more)
You have no idea how hard that post was to write. I mean, it's so hard to read Dr. Kruse's writing and find consistant threads in it. He has references on the bottom of some post, but mostly they do not correspond to things in his posts that I... (more)
I know that strict paleo doesn't include grains, dairy or legumes. However, I think the majority of people here are flexible with what they eat. Butter and cream seem to be sacred gods on this site. I was wondering if I could do some sort of poll... (more)
If both your great-grandparents had a Paleo lifestyle and passed it down, how would your body fare today? Are we supposed to eat like our cultural ancestors or did your genetics get hampered because of some of the food they did or didn't eat?... (more)
I have a question that has been on my mind for a while now, and I am wondering what some other people think of this. So, having been strict Paleo for over a year now, that is my choice, I know that. my Significant other, is a wonderfully... (more)
It may not be a helpful answer, but I'd really recommend trying to look beyond weight as the only measure of health. I'd also be cautious of drawing conclusions about what other people are eating or doing when you don't see them. I'm sure there... (more)
You probably are not looking for grounds upon which to sue 23andme, but... The word "actionable" means "affording grounds for legal action" and "violating principles of justice." I get that you mean something closer to: "Based on one's genome,... (more)
Hi! Who here legitimately forgets to eat? Or has less interest in food than people in general? I've had a brief history of overeating, but that was due to addictive foods on the S.A.D that I leeched onto after being through a long period of... (more)
Pyroluria-- Is it real? Is it permanent? Those that pay attention to it regard it as genetic, requiring permanent B6 supplementation. Nora Gedgaudas in "Primal Mind Primal Body" has a whole appendix on it and seems to share this view. Any... (more)
EDIT: Other PH posts are slightly different: My post is about my specific results. I took this genetic test because I am at the bottom of the barrel as far as stuff to try for my health issues. So help me with a little speculation on trying to... (more)
Paleo/ holistic doctors in Hawaii?
What is the best brand of hamburgers in East Wichita?
Do you agree with paleo-censorship?