Genetics

Genetics

Genetics Questions

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by 952 · 28 minutes ago

Did you anyone took specific actions based on microbiome sequencing?

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by 9647 · 30 minutes ago

Just the question as it stands, really. Is anyone out there familiar enough with this academic community to know if the diet has taken on? And when I say anthropologists I mean the scientific kind (physical anthropology, etc.), not the ones who... (more)

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Patrik 0 · October 09, 2010 at 10:59 PM

This is gonna be a fun one. Gonna approach in a pretty similar manner to Matthew. Full disclosure: I hold a BA in Physical Anthropology from university that houses some of the "rock-stars" of evolutionary psychology (a branch of physical... (more)

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by 1005 · about 1 hour ago

I'm looking for any suggestions for eating / supplementing with this in mind:

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Colin_1 0 · July 20, 2013 at 4:19 PM

You have different mutations than me so I'm not much help, but here are some good... (more)

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by 0 · about 1 hour ago

Hi, I have recently taken Genova's DetoxiGenomic Profile. Apparently I am absent of the GSTM! Glutathione gene. If glutathione supplementation is useless, what would you recommend I do? Regards, Neil.

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glutathione_pro 0 · November 01, 2013 at 12:13 AM

Glutathione supplementation is no longer useless. While most glutathione supplements are ineffective because they are broken down in the gut before they can be absorbed, you can overcome this. Either supplementing with the precursors of... (more)

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by 1346 · about 1 hour ago

We are our genes, but our genes are not our fate. As a paleo community we tend to concern ourselves greatly with our natural heritage, our predispositions and our gene expressions. We are very interested in bringing out the best of what we are and... (more)

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animalcule 0 · March 15, 2013 at 6:05 AM

Most things about the way any modern human looks are a mixture of genetics, epigenetics, and environment/nurture/'the kitchen'. This is certainly true of that particular anatomical feature. I'm not muscular (thin), don't have crazy low body fat,... (more)

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by 952 · about 1 hour ago

Anyone tried it? What is better NAC or gluthaionine? I found this interesting paper which supports supplementation with NAC and couple of other gluthaionine precursors: http://www.ncbi.nlm.nih.gov/pubmed/17914184 Any APOE 4/4 who actually tried... (more)

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by 952 · about 1 hour ago

Dear all! What do you think about creating the ultimate hacking thread for Apo-??4/??4 gene mutations to discuss practical real-life implications. What worked and what did not for cholesterol numbers and overall well-being in terms of lifestyle,... (more)

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Cave_Chick 0 · March 12, 2013 at 10:49 PM

According to 23andme I'm a 4/4 (and 3.1% Neanderthal!) and I notice MUCH better energy, cognition and fat loss when I eat large amounts of coconut oil daily. High quality coconut oil can be expensive, so at times I've stopped buying it to save... (more)

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by 631 · about 1 hour ago

Hey all, I need to do a genetics paper, and it's pretty free reign. This is the assignment: The Final Project A term paper is required. The term paper is due when you turn in your final assignment. Please submit the paper as a Microsoft Word... (more)

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David_Moss 0 · January 19, 2013 at 9:34 PM

How substantial the alteration of our genetics has been since the neolithic? I don't know whether that meets the remit or is too macro an issue. Consider this summary of the debate on wikipedia: According to Alexander Str??hle, Maike ... (more)

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by 240 · about 2 hours ago

I just wonder why it happens?

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Kashkillz 0 · December 06, 2012 at 10:06 PM

Kettlebell... squats... lunges... plyometrics... You are not a victim!!!

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by 213 · about 2 hours ago

Did you learn something that lead to a significant change in your daily routine? Do you think your health will be even better now that you have this new information? Do you trust the results? Do you think the science is too young to be... (more)

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balor123 0 · November 30, 2012 at 9:50 PM

I used 23andme and Promethease as well. I was having some difficult to diagnose health problems and I thought that the genetic tests might help me narrow down other tests to pursue. People usually focus on the disease risk factors but it's worth... (more)

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by 213 · about 2 hours ago

Is this done through one's doctor, or is there a more accurate genetic testing method that one's doctor might not be aware of? Is there a lab out there that studies this particular genetic condition that also offers testing to the public? I am... (more)

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JRM 0 · November 28, 2012 at 3:48 AM

23andme.com is probably cheaper than going to your doctor. I tested there and found out I don't carry the mutations.

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by 4181 · about 2 hours ago

I don't see my dad that much but when I did the other day I noticed that his skin is not great, my mum's seems ok but i think she wears foundation. My own skin is not great also, quite a few bumps and spots which don't really bother me too much... (more)

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miked_2 0 · August 07, 2012 at 9:29 PM

I'm firmly in the lifestyle camp. What I mean by that is that while your genes determine your potential, your lifestyle affects the expression of those genes (epigenetics). Your DNA is just a list of instructions for things, however whether or... (more)

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by 72 · about 2 hours ago

My son (1.5yo) was just diagnosed with a very, very rare genetic disorder (Primary Hyperoxaluria Type III). The specialist who actually described this disease hypothesises that the genetic mutation causes the pathway for the proper breakdown of... (more)

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Matt_11 0 · July 28, 2012 at 12:24 PM

Not sure I understand how a vegan diet minimizes oxalates... which is the problem with hyperoxaluria. Oxalates are absent in animal products, and present in many plant foods. I'm guessing it stresses the kidneys so they're just trying to minimize... (more)

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by 56616 · about 2 hours ago

I was talking with some relatives who have stomach problems and one thing I noticed is that a lot of them are on NSAIDs- ibuprofen and aspirin, for example. Over the years I have been on and off the paleo diet, but never gotten back to the point I... (more)

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Stephen_5 0 · June 23, 2012 at 2:48 PM

You wrote: The GI bleeding must just be the tip of the iceberg, there much be other damage occurring before it comes to that. Actually, GI bleeds are probably the initial and biggest side effect of NSAIDs. It happens very quickly, it... (more)

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by 0 · about 2 hours ago

I'm being hopeful... This is a long shot and I'm pretty sure nobody will answer...but is there anyone with NF out there who is on paleo? Do you think that it will help with any of the symptoms? Thanks in advance.

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LaurenM 0 · April 15, 2012 at 9:54 AM

You have probably already found this, but the only lead I could find (hopefully more knowledgeable people can either discredit or use as a springboard) was here:... (more)

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by 5509 · about 2 hours ago

I know that strict paleo doesn't include grains, dairy or legumes. However, I think the majority of people here are flexible with what they eat. Butter and cream seem to be sacred gods on this site. I was wondering if I could do some sort of poll... (more)

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Nance 0 · March 28, 2012 at 12:20 AM

I'd have to say many of my reactions to food would be compatible with a hunting/gathering ancestry. I hope you get lots of diverse responses. Russian, Polish and Scottish are my dominant ancestries. Experimentation and use of probiotics has... (more)

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by 871 · about 2 hours ago

I have a question that has been on my mind for a while now, and I am wondering what some other people think of this. So, having been strict Paleo for over a year now, that is my choice, I know that. my Significant other, is a wonderfully... (more)

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PrimalDanny 0 · February 22, 2012 at 12:09 AM

It may not be a helpful answer, but I'd really recommend trying to look beyond weight as the only measure of health. I'd also be cautious of drawing conclusions about what other people are eating or doing when you don't see them. I'm sure there... (more)

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by 952 · about 2 hours ago

Have you extracted any actionable, effective and yet counter-intuitive (to conventional wisdom and general paleo knowledge) conclusions from 23andme or other genetic testing companies?

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Dorado_Galore 0 · February 15, 2012 at 8:24 PM

You probably are not looking for grounds upon which to sue 23andme, but... The word "actionable" means "affording grounds for legal action" and "violating principles of justice." I get that you mean something closer to: "Based on one's genome,... (more)

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by 1186 · about 2 hours ago

Pyroluria-- Is it real? Is it permanent? Those that pay attention to it regard it as genetic, requiring permanent B6 supplementation. Nora Gedgaudas in "Primal Mind Primal Body" has a whole appendix on it and seems to share this view. Any... (more)

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Harry_3 0 · May 16, 2012 at 10:56 AM

Oh its real alright. I have Pyroluria, it took me 8 years to work out what caused all my symptoms, these symptoms included: Brain fog Poor concentration and memory Depression Anxiety Chronic fatigue (really adrenal fatigue) Digestive... (more)

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by 4080 · about 2 hours ago

EDIT: Other PH posts are slightly different: My post is about my specific results. I took this genetic test because I am at the bottom of the barrel as far as stuff to try for my health issues. So help me with a little speculation on trying to... (more)

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Amy_10 0 · September 12, 2011 at 10:15 PM

Senneth, Your tummy problems may be covering up your ability to have high iron. If your diarrhea dominant, your iron may be just running out of you. If your constipated your iron levels should hypothetically be higher. Generally, people who are... (more)

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by 1801 · about 2 hours ago

A friends status on FB got me thinking about this. Her son was using a toy as a gun. She has no idea how he knows about guns. A few comments suggested that boys just do this kind of thing - it's genetic. My DS is always surprising me and using... (more)

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wildthing 0 · August 30, 2011 at 9:34 PM

My 2 boys used ANYTHING as a gun. Sticks, leaves, broken toys. My nephew had two older sisters who dressed him up in their ballet clothes...he broke out and put on a super hero cape and moon boots...he wore it every where. Everything more than... (more)

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by 5002 · about 3 hours ago

I've always wondered if the different levels in carb tolerance that we often see has anything to do with genetic differences that related to ethnicity. I, for example, am half Italian (mother born there) and half Jewish-Russian (perhaps Belarus;... (more)

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Andy 0 · August 03, 2011 at 1:21 AM

Scotch/Irish and Seminole/Cherokee... very sensitive to carbs. I get fat easily if I eat too many, my blood sugar gets too high. Even when it comes to alcohol, I simply cannot tolerate it. 2 drinks and I'm done. But on the reservation, the... (more)

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by 12174 · about 3 hours ago

Non-Africans Are Part Neanderthal, Genetic Research Shows http://www.sciencedaily.com/releases/2011/07/110718085329.htm In light of these findings, is there anything that we can extrapolate about the nutritional needs (such as macronutrient... (more)

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Matt_1 0 · July 18, 2011 at 11:05 PM

Some non-African populations, sometimes mentioned here, with quite varying traditional diets include: Okinawans Chinese Kitavans Inuit Plains Indians Italians French Australian aborigines If all these populations are equally decended from... (more)

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by 56616 · about 3 hours ago

Chris and I were having a conversation about how some people do really awesome on pretty low carb and some people feel sick. I started getting curious about whether this might have something to do with "neanderthal ancestry." If you have DNA data... (more)

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Rose 0 · July 18, 2011 at 8:08 PM

What a great little gadget! I just ran mine and got a score of 20. I've been thriving on a "zero-carb" diet for the last two years, and have found that vegetables -- with the exception of some nuts (walnuts, macadamias) and dark leafy greens (e.g.... (more)

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by 50 · about 3 hours ago

The show is about how we all started in Africa and migrated north then one group heads west and another group goes east. We lightened up the further north we went to be able to get the most amount of Vit D with shorter days I guess. But then how... (more)

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Bisous_1 0 · November 13, 2010 at 5:24 PM

There's also evidence that European light skin and different colors of hair might have a lot to do with sexual selection in addition to issues with vitamin D.

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