Genetics

Genetics

Genetics Questions

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by 952 · about 23 hours ago

Did you anyone took specific actions based on microbiome sequencing?

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by 9647 · about 23 hours ago

Just the question as it stands, really. Is anyone out there familiar enough with this academic community to know if the diet has taken on? And when I say anthropologists I mean the scientific kind (physical anthropology, etc.), not the ones who... (more)

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Patrik 0 · October 09, 2010 at 10:59 PM

This is gonna be a fun one. Gonna approach in a pretty similar manner to Matthew. Full disclosure: I hold a BA in Physical Anthropology from university that houses some of the "rock-stars" of evolutionary psychology (a branch of physical... (more)

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by 0 · about 23 hours ago

Hi, I have recently taken Genova's DetoxiGenomic Profile. Apparently I am absent of the GSTM! Glutathione gene. If glutathione supplementation is useless, what would you recommend I do? Regards, Neil.

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glutathione_pro 0 · November 01, 2013 at 12:13 AM

Glutathione supplementation is no longer useless. While most glutathione supplements are ineffective because they are broken down in the gut before they can be absorbed, you can overcome this. Either supplementing with the precursors of... (more)

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by 1336 · about 23 hours ago

We are our genes, but our genes are not our fate. As a paleo community we tend to concern ourselves greatly with our natural heritage, our predispositions and our gene expressions. We are very interested in bringing out the best of what we are and... (more)

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animalcule 0 · March 15, 2013 at 6:05 AM

Most things about the way any modern human looks are a mixture of genetics, epigenetics, and environment/nurture/'the kitchen'. This is certainly true of that particular anatomical feature. I'm not muscular (thin), don't have crazy low body fat,... (more)

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by 952 · about 23 hours ago

Anyone tried it? What is better NAC or gluthaionine? I found this interesting paper which supports supplementation with NAC and couple of other gluthaionine precursors: http://www.ncbi.nlm.nih.gov/pubmed/17914184 Any APOE 4/4 who actually tried... (more)

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by 952 · about 23 hours ago

Dear all! What do you think about creating the ultimate hacking thread for Apo-??4/??4 gene mutations to discuss practical real-life implications. What worked and what did not for cholesterol numbers and overall well-being in terms of lifestyle,... (more)

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Cave_Chick 0 · March 12, 2013 at 10:49 PM

According to 23andme I'm a 4/4 (and 3.1% Neanderthal!) and I notice MUCH better energy, cognition and fat loss when I eat large amounts of coconut oil daily. High quality coconut oil can be expensive, so at times I've stopped buying it to save... (more)

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by 952 · about 23 hours ago

For those who got APOE 4/4 result on genetic testing (http://snpedia.com/index.php/APOE). What have you learned during your experimentation with diet, supplementation and with overall lifestyle changes?

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Alex 0 · February 25, 2013 at 2:22 PM

I'm E4/E4. During my 20s and 30s, my diet was heavily influenced by Indian vegetarianism, with a heavy emphasis on grains and beans. This resulted in a flabby, lethargic descent into middle age. In September 2003, I drastically cut back on all... (more)

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by 631 · about 23 hours ago

Hey all, I need to do a genetics paper, and it's pretty free reign. This is the assignment: The Final Project A term paper is required. The term paper is due when you turn in your final assignment. Please submit the paper as a Microsoft Word... (more)

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David_Moss 0 · January 19, 2013 at 9:34 PM

How substantial the alteration of our genetics has been since the neolithic? I don't know whether that meets the remit or is too macro an issue. Consider this summary of the debate on wikipedia: According to Alexander Str??hle, Maike ... (more)

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by 240 · about 23 hours ago

I just wonder why it happens?

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Kashkillz 0 · December 06, 2012 at 10:06 PM

Kettlebell... squats... lunges... plyometrics... You are not a victim!!!

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by 213 · about 23 hours ago

Is this done through one's doctor, or is there a more accurate genetic testing method that one's doctor might not be aware of? Is there a lab out there that studies this particular genetic condition that also offers testing to the public? I am... (more)

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JRM 0 · November 28, 2012 at 3:48 AM

23andme.com is probably cheaper than going to your doctor. I tested there and found out I don't carry the mutations.

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by 504 · about 23 hours ago

Since there is talk about gaining weight all over paleo hacks, i was wondering when played defensive end in high school when i weighed 240 (im 190 now) i was benching 325 for reps, powercleaning 260 for reps, and deadlifting 450-480 pounds, this... (more)

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paleohacks 0 · October 24, 2012 at 7:40 AM

For that type of very respectable performance most definitely genetics. There aren't too many 18 year olds benching 325 for reps without the gear, unless they've been dealt a good hand of genes. As always, be grateful to your parents :) (more)

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by 78422 · about 23 hours ago

You know those guys you see who are naturally muscular and barely lifts weights? How do you explain that? I kind of envy them. I have sucky genetics and have to work my ass off for every inch of muscle i gain. Thoughts?

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by 78422 · about 23 hours ago

Is it paleo to masturbate too much? Should i save my for loads for procreation purposes only? Will i ever get to pass my genes on?

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red_leaf 0 · August 06, 2012 at 1:22 AM

I know we like food and all but... don't feed the troll.

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by 72 · about 23 hours ago

My son (1.5yo) was just diagnosed with a very, very rare genetic disorder (Primary Hyperoxaluria Type III). The specialist who actually described this disease hypothesises that the genetic mutation causes the pathway for the proper breakdown of... (more)

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Matt_11 0 · July 28, 2012 at 12:24 PM

Not sure I understand how a vegan diet minimizes oxalates... which is the problem with hyperoxaluria. Oxalates are absent in animal products, and present in many plant foods. I'm guessing it stresses the kidneys so they're just trying to minimize... (more)

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by 413 · about 23 hours ago

Just to clarify, the title was just a way of posing this as a question. Obviously the NY times just report the news, so I don't hold them responsible for reporting this crap, but it was prescient enough and is trending on a prolific tech news... (more)

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paleohacks 0 · July 14, 2012 at 11:40 PM

This part is particularly troubling: "Did people unexpectedly gain or lose weight when they had the same amount of calories but in a diet of a different composition?" No. There was zero difference between high-fat and low-fat diets. Despite... (more)

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by 78422 · about 23 hours ago

Paleo is a wonderful notion - to emphasise the dietary practices that our bodies, due to evolution, are best suited to. This principle seems to work particularly well when compared with diet plans that are extremely unsuited to the expectations... (more)

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Shari_Bambino 0 · July 01, 2012 at 12:43 PM

As far as I can see we have already done that. Recreationists or the rigid thinkers are pretty much shunned as extremists which is as it should be IMO. It seems to me that most involved in the paleo movement are very sensitive to individual needs... (more)

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by 56616 · about 23 hours ago

I was talking with some relatives who have stomach problems and one thing I noticed is that a lot of them are on NSAIDs- ibuprofen and aspirin, for example. Over the years I have been on and off the paleo diet, but never gotten back to the point I... (more)

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Stephen_5 0 · June 23, 2012 at 2:48 PM

You wrote: The GI bleeding must just be the tip of the iceberg, there much be other damage occurring before it comes to that. Actually, GI bleeds are probably the initial and biggest side effect of NSAIDs. It happens very quickly, it... (more)

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by 1439 · about 23 hours ago

When we observe the diets of primitive tribes currently still in or close to the stone age, we see that they vary quite a bit. For example, the Kitava Island folks eat a lot of carbs (by our "paleo" standards), and the Inuit-like folks in north... (more)

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paleohacks 0 · May 28, 2012 at 5:34 PM

So what is the question?

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by 0 · about 23 hours ago

I'm being hopeful... This is a long shot and I'm pretty sure nobody will answer...but is there anyone with NF out there who is on paleo? Do you think that it will help with any of the symptoms? Thanks in advance.

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LaurenM 0 · April 15, 2012 at 9:54 AM

You have probably already found this, but the only lead I could find (hopefully more knowledgeable people can either discredit or use as a springboard) was here:... (more)

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by 5002 · about 23 hours ago

I'll start with my question: Do you agree with Melissa McEwen's critique of Jack Kruse's (mis)use of evolutionary biology? I should note that I am a fan of both McEwen and Kruse. McEwen's blog post is... (more)

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Bread_Eating_Beelzebub 0 · April 02, 2012 at 3:34 AM

You have no idea how hard that post was to write. I mean, it's so hard to read Dr. Kruse's writing and find consistant threads in it. He has references on the bottom of some post, but mostly they do not correspond to things in his posts that I... (more)

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by 5509 · about 23 hours ago

I know that strict paleo doesn't include grains, dairy or legumes. However, I think the majority of people here are flexible with what they eat. Butter and cream seem to be sacred gods on this site. I was wondering if I could do some sort of poll... (more)

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Nance 0 · March 28, 2012 at 12:20 AM

I'd have to say many of my reactions to food would be compatible with a hunting/gathering ancestry. I hope you get lots of diverse responses. Russian, Polish and Scottish are my dominant ancestries. Experimentation and use of probiotics has... (more)

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by 203 · about 23 hours ago

Hi! Because of constipation, which is now better, my G.I specialist got me to take a blood test to see if I have celiac or not. The results were that I'm a carrier for Celiac disease but it came back negative. My aunt didnt develop properly... (more)

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Mscott 0 · March 24, 2012 at 3:07 AM

If you haven't been eating gluten leading up to the blood test the ability of the test to identify celiac disease drops considerably. I know someone who stopped eating gluten, felt much much better, then went to the doctor a few weeks later to be... (more)

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by 2682 · about 23 hours ago

How much do you consider your family history (or gene testing, if you've done it) when making lifestyle decisions? For example, if you find out tomorrow that many of your older relatives had/have a particular cancer, would you begin to make... (more)

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Sarah_14 0 · February 27, 2012 at 7:00 PM

I don't consider myself a genetics expert, but I am married to one. Many people ask him if they should get tested for certain things, especially if they are adopted or have family history of cancer, etc. He will always say the same thing: "If... (more)

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by 871 · about 23 hours ago

I have a question that has been on my mind for a while now, and I am wondering what some other people think of this. So, having been strict Paleo for over a year now, that is my choice, I know that. my Significant other, is a wonderfully... (more)

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PrimalDanny 0 · February 22, 2012 at 12:09 AM

It may not be a helpful answer, but I'd really recommend trying to look beyond weight as the only measure of health. I'd also be cautious of drawing conclusions about what other people are eating or doing when you don't see them. I'm sure there... (more)

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by 952 · about 23 hours ago

Have you extracted any actionable, effective and yet counter-intuitive (to conventional wisdom and general paleo knowledge) conclusions from 23andme or other genetic testing companies?

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Dorado_Galore 0 · February 15, 2012 at 8:24 PM

You probably are not looking for grounds upon which to sue 23andme, but... The word "actionable" means "affording grounds for legal action" and "violating principles of justice." I get that you mean something closer to: "Based on one's genome,... (more)

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