Leptin

Leptin

Leptin Questions

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by 0 · about 20 hours ago

I began my paleo diet and bio hacking adventure about 18 months ago, but feel I have hit a brick wall and need some help to better understand my labs and situation. I???m hoping that someone might be able give me some deeper insights on reactive... (more)

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by 10 · about 20 hours ago

Hi I'm 19 obese male, 230 pounds. I just have a few questions I would like answered based on your own experience and knowledge. 1.) Is it better for me to buy mainly grass fed tallow or cold pressed coconut oil? I am on a budget now and so I... (more)

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NewPaleon 0 · July 20, 2013 at 4:23 PM

When I started Paleo a year ago, I had awful cravings for cookies, chips, etc. Then I read the Perfect Health Diet and started eating 1/2 - 1 cup of white rice with lunch and dinner and my cravings are mostly gone. I also do IF most days.... (more)

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by 112 · about 20 hours ago

The thing I do not understand is what the body does in relation to excess fat intake, if we assume a low-carb diet. Apparently acylation stimulating protein is created in response to chylomicrons which exist after eating fat, and can thus cause... (more)

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Anon_9 0 · April 08, 2013 at 11:17 PM

I don't know about you, but sometimes excess fat passes right through me, if you know what I mean. One of the consideration with eating that most people forget is that not everything you eat gets burned or stored. Sometimes it's broken down and... (more)

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by 100 · about 20 hours ago

Made the mistake of going too low carb and stubbornly sticking with it for a year despite rapid weight gain. Just realized that my symptoms (lack of energy, cold extremities and puffy face) was from a sluggish thyroid. Even have slight darkening... (more)

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Lumifer_1 0 · April 30, 2013 at 2:35 PM

Um, go to a doctor and ask for a thyroid panel blood test. Make sure it includes free T3 beside TSH and the other usual stuff. If you think you have serious problems with your thyroid, get the hard data, don't rely on "it seems my symptoms could... (more)

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by 638 · about 20 hours ago

Ok so I have always been a morning exerciser.. It leaves me feeling pretty good the whole day, plus the gym is about 90% less packed in the morning and its easy to find a park... and lets be honest, I am much more likely to exercise if I can do at... (more)

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James_3 0 · March 16, 2013 at 10:59 PM

My recollection on the Leptin Reset Protocol is that is for people that are Leptin resistant. If you aren't Leptin resistant, it doesn't apply to you. ie. exercise when you want. If you're Leptin resistant, he doesn't want you exercising... (more)

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by 83 · about 20 hours ago

I know eating sugar/bad carbs will change your brain chemistry and mess up your leptin (Im not to sure if thats the correct use of the term) Is it possible to restore your body and brain from adapting a paleo lifestyle? Reset your leptin? Will it... (more)

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ShakenTreasureTroll 0 · February 11, 2013 at 5:45 AM

Hormones autoregulate really well. I would suggest NOT looking at any specific thing to try and manipulate hormones directly. I would just eat a healthy diet, get some sleep and don't obsess about Paleo Purity too much.

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by 55 · about 20 hours ago

Dear Paleo Hacks, I have been eating strict paleo for about 2 years. I found paleo after battling severe IBS with constipation. I have since transitioned into the full GAPS diet and am intent on doing GAPS intro this coming winter. My current... (more)

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Mimi_1 0 · November 29, 2012 at 6:26 AM

"Some kind of protein"? Elaborate , please. Change your 85/15 beef to 80/20, if you're eating lean meats, switch to fattier cuts of meat. If I ever have to cook lean meat, I always cook it with lots of heavy cream or coconut milk, or I make sure... (more)

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by 435 · about 20 hours ago

I have read Paleo Solution and It Starts With Food, both of which talk about leptin and other hormones. Specifically, these books claim that following their respective diets will help get these hormones back in balance. Then Jack Kruse comes... (more)

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August 0 · October 18, 2012 at 7:19 PM

Eating 50g protein for breakfast is excessive and it breaks the 'if you aren't hungry, don't eat' rule. Jack's stuff is basically low carb paleo with a used car salesman's smarm and Disneyland shine. In other words, he's got some interesting... (more)

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by 1187 · about 20 hours ago

Short question: Have you done carb nite and did it work for you? Long Question: Am I doing this wrong? Why isn't it working? My info below. About me: 5'2, 150.4 lbs. 38 years old female. Metabolically disordered much of my life. I've lost 20... (more)

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nthmost 0 · September 14, 2012 at 11:23 PM

I've worked with a couple of women like you who've done heavy keto and then switched to Carb Nite and didn't see results. Doing long term keto really fraks with your thyroid and leptin levels and it takes time to get them back where they should... (more)

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by 90 · about 20 hours ago

"Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity " Here's an interesting study - forget about the Glycemic Index, as... (more)

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Beth_WeightMaven 0 · July 16, 2012 at 12:23 PM

This is not a study, it's a hypothesis. The full text is available as a PDF download and I think it's well worth a read. Here's the author's conclusion: The increased storage life and convenience of some of our oldest agricultural products... (more)

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by 6229 · about 20 hours ago

Just curious if anyone has had this response to xylitol. Has your sense of sweetness been desensitized by continuing to use sweeteners? When you pull xylitol out do you notice almost everything including veggies like tomatoes and cabbages tastes... (more)

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SUSTAINEDfitness 0 · July 13, 2012 at 3:50 AM

The only sweetener I use is a little xylitol, and to me everything has tasted sweeter anyway since going primal/paleo. I feel that what desensitized people to sweets is the constant sugary drinks most people have. Since giving up soda, even the... (more)

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by 6709 · about 20 hours ago

Do you think an entire box of rice cereal and a half gallon of milk is enough to 'reset my leptin'?

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Jay_15 0 · July 06, 2012 at 2:39 AM

No...you need to smoke some crack with it.

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by 161 · about 21 hours ago

I saw the other similar topics, but while they provide some solutions, i didn't see many explanations in them. I have been paleo for two months and already lost one sixth of my weight. I have also been doing Leptin Reset for around three... (more)

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Don_1 0 · June 22, 2012 at 1:49 AM

You're putting too much faith in labels such as "leptin reset" and "adrenal fatigue". We are very complex and adaptable. Changes in your diet may be helpful, but the concepts you discuss are, at best, vastly simplistic. Either up your carbs, or... (more)

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by 90 · about 21 hours ago

I guess this is part Catharsis but there is a question in here, I promise. For as long as I can remember have been the guy that did not push himself away from the dinner table until my belly felt like it was going to bust. I simply did not feel... (more)

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Matthew_Caton 0 · May 26, 2012 at 5:41 PM

It is very possible that you have regained leptin sensitivity. In your first paragraph you described a scenario that is not far off from the truth. Peptide YY is a gut hormone that is released in response to mainly protein, and to a lesser extent... (more)

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by 135 · about 21 hours ago

I've read Metabolic Reset: A Binge and Purge Manifesto, I know a very interesting title. I find the book extremely intriguing. It combines 3 things that I find integral to losing fat and preserving and building lean muscle. That being High Fat,... (more)

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Eugenia 0 · May 21, 2012 at 5:22 AM

I personally do not have faith in your Sunday regimen. If you eat gluten, and you're gluten-intolerant as 7/10 people on this world are (according to new studies), then you can undo a lot of good progress your body made during the week. According... (more)

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by 6418 · about 21 hours ago

Read it and consider: http://jackkruse.com/the-holy-trinity-ct-4/ Are you open to trying The Quilt's life plan? "A VLCer will always look average, but will a decent lifespans but they will never see optimal either. What is the name of my... (more)

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none 0 · February 28, 2012 at 1:54 AM

Drinks malbec from a box, sits in a tub full of ice, loads up on Tim Ferris and catches up on Robin Sharma tweets, stands back in amazment at the truth that unfolds!!! Shall I genuflect? Cross myself? Anoint myself in the waters of Lake... (more)

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by 15003 · about 21 hours ago

What: The Paleo Summit (see also this post) Who: Dr. Jack Kruse MD ??? Neurosurgeon Topic: Leptin Circadian Cycles. Dr. Kruse uncovers how leptin resistance lies at the root of inflammation, obesity, and chronic disease. He also shares how he... (more)

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Kurt_Harris_MD 0 · March 08, 2012 at 5:21 AM

Reading the discussion of Kruse's emissions here reminds me of nothing so much as Being There by Jerzy Kosinski. People apparently will take anything seriously, to the point where the more incoherent and implausible it sounds, the more profound... (more)

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by 161 · about 21 hours ago

I have been paleo now for 22 days. Have lost about 4kgs. I have been hearing a lot about this leptin reset. Tried looking up google, but everyone has a different explanation about it. Can anyone please explain it to me in simple terms. What... (more)

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Eric_12 0 · February 12, 2012 at 6:39 AM

Here it is: Dr Kruse says it best and this is a one page description: http://jackkruse.com/my-leptin-prescription/ It is very effective if you are leptin resistant.... (more)

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by 144 · about 21 hours ago

Anyone have thoughts about Dr. Rosedale's recent appearance on Jimmy Moore's podcast? He essentially distinguishes his leptin reset plan from Dr. Kruse's by recommending a much lower amount of protein, saying that the amount of protein... (more)

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August 0 · January 25, 2012 at 9:45 PM

Rosedale's thing on protein is that he doesn't want to trigger growth. This is based on research on the MTOR pathway. Protein over 20g at a meal supposedly triggers this pathway, as does carbohydrates. The researchers made a worms live longer... (more)

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by 1579 · about 21 hours ago

Hello. I am having some success restoring weight lost due to an eating disorder and am getting close to no longer being underweight. I am wondering if a leptin reset would be a good idea, to fix my metabolism which I assume is still not... (more)

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Mallory_1 0 · January 22, 2012 at 2:02 AM

get weight restored, see your doctor helping your recovery and get tests, then decide what you need to do. weight restoration is not a number, it is a place, mental and physical that your blood work can reflect. if it isnt up to par, hormones are... (more)

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by 45 · about 21 hours ago

According to much of the advice I've read surrounding leptin, the leangains approach is not very healthy. Skipping breakfast, eating at night, etc. I've tried each of them and leangains works much better for me. I'm just not very hungry in the... (more)

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Jeff__1 0 · January 19, 2012 at 11:45 PM

The leptin 'rules' are meant to reset sensitivity, as mentioned above. As someone who is leptin sensitive, I still follow the 'rules' for the most part and it really works well. I also include some IF as well as fasted workouts however. Eating... (more)

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by 15226 · about 21 hours ago

What is leptin's relationship to PEPCK? Does it stimulate or suppress it? Would love to hear thoughts on this from the sciencey types on here. edit: I think it's probably got to increase PEPCK... the second study measured a short term leptin... (more)

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akman 0 · July 03, 2012 at 9:12 PM

The Quilt is so far ahead of his time it's not funny. His year old posts are just starting to make sense. From today at http://medicalxpress.com/news/2012-07-discovery-cellular-pathways-converge-food.html : Now, researchers at Beth Israel... (more)

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by 2861 · about 21 hours ago

Do carbs ???spike??? leptin? This seems to be a central tenet to Dr. Rosedale???s science, but it appears to be false according to Carbsane. Is there any more evidence either way that anybody wants to share? (more)

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Lucas_Tafur 0 · November 29, 2011 at 3:27 PM

Yes, carbs raise leptin, but not in a "spiky" fashion. Edited to answer Evelyn: I think it is important to differentiate postprandial effects from chronic effects, ie. which show alteration of its pulsatile/circadian secretion. For... (more)

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by 121 · about 21 hours ago

Jack Kruse: http://jackkruse.com/my-leptin-prescription/ (This is intended for 6-8 weeks or until leptin sensitive and a paleo diet post reset.) Ron Rosedale's website: http://drrosedale.com/healthplan.htm (I included Rosedale's b/c his was... (more)

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Andre_Chimene 0 · November 07, 2011 at 6:59 AM

Melissa, I love you and your blog, I am a fan...but Rosedale is not saying fish and chicken are healthier than beef or lamb. He is saying in the first 3 weeks, to become a more efficient ketone burner, limit SAT fat till you are on the beam. Then,... (more)

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by 253 · about 21 hours ago

First, a little background. I'm a pretty fit person, 24 yrs old, 6' tall 185 lbs I don't know exactly what my body fat is but I would guess somewhere in the 8-12% range. My problem is trying to use my diet to maximize energy levels. Due to my job... (more)

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Jamie_2 0 · November 05, 2011 at 1:03 PM

I know that I've read that Chris Masterjohn (the daily lipid blog) has stated that carbs before bed help him sleep. There's also a book called "Lights Out" that I believe recommends a spoonful of raw honey before bed to help with sleep. I WISH I... (more)

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