Leptin

Leptin

Leptin Questions

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by 112 · about 10 hours ago

The thing I do not understand is what the body does in relation to excess fat intake, if we assume a low-carb diet. Apparently acylation stimulating protein is created in response to chylomicrons which exist after eating fat, and can thus cause... (more)

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Anon_9 0 · April 08, 2013 at 11:17 PM

I don't know about you, but sometimes excess fat passes right through me, if you know what I mean. One of the consideration with eating that most people forget is that not everything you eat gets burned or stored. Sometimes it's broken down and... (more)

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by 50 · about 10 hours ago

If so, how did it work for you? The company that makes it looks pretty legit.

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by 100 · about 10 hours ago

Made the mistake of going too low carb and stubbornly sticking with it for a year despite rapid weight gain. Just realized that my symptoms (lack of energy, cold extremities and puffy face) was from a sluggish thyroid. Even have slight darkening... (more)

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Lumifer_1 0 · April 30, 2013 at 2:35 PM

Um, go to a doctor and ask for a thyroid panel blood test. Make sure it includes free T3 beside TSH and the other usual stuff. If you think you have serious problems with your thyroid, get the hard data, don't rely on "it seems my symptoms could... (more)

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by 638 · about 10 hours ago

Ok so I have always been a morning exerciser.. It leaves me feeling pretty good the whole day, plus the gym is about 90% less packed in the morning and its easy to find a park... and lets be honest, I am much more likely to exercise if I can do at... (more)

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James_3 0 · March 16, 2013 at 10:59 PM

My recollection on the Leptin Reset Protocol is that is for people that are Leptin resistant. If you aren't Leptin resistant, it doesn't apply to you. ie. exercise when you want. If you're Leptin resistant, he doesn't want you exercising... (more)

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by 55 · about 10 hours ago

Dear Paleo Hacks, I have been eating strict paleo for about 2 years. I found paleo after battling severe IBS with constipation. I have since transitioned into the full GAPS diet and am intent on doing GAPS intro this coming winter. My current... (more)

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Mimi_1 0 · November 29, 2012 at 6:26 AM

"Some kind of protein"? Elaborate , please. Change your 85/15 beef to 80/20, if you're eating lean meats, switch to fattier cuts of meat. If I ever have to cook lean meat, I always cook it with lots of heavy cream or coconut milk, or I make sure... (more)

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by 435 · about 10 hours ago

I have read Paleo Solution and It Starts With Food, both of which talk about leptin and other hormones. Specifically, these books claim that following their respective diets will help get these hormones back in balance. Then Jack Kruse comes... (more)

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August 0 · October 18, 2012 at 7:19 PM

Eating 50g protein for breakfast is excessive and it breaks the 'if you aren't hungry, don't eat' rule. Jack's stuff is basically low carb paleo with a used car salesman's smarm and Disneyland shine. In other words, he's got some interesting... (more)

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by 1187 · about 10 hours ago

Short question: Have you done carb nite and did it work for you? Long Question: Am I doing this wrong? Why isn't it working? My info below. About me: 5'2, 150.4 lbs. 38 years old female. Metabolically disordered much of my life. I've lost 20... (more)

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nthmost 0 · September 14, 2012 at 11:23 PM

I've worked with a couple of women like you who've done heavy keto and then switched to Carb Nite and didn't see results. Doing long term keto really fraks with your thyroid and leptin levels and it takes time to get them back where they should... (more)

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by 6229 · about 10 hours ago

Just curious if anyone has had this response to xylitol. Has your sense of sweetness been desensitized by continuing to use sweeteners? When you pull xylitol out do you notice almost everything including veggies like tomatoes and cabbages tastes... (more)

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SUSTAINEDfitness 0 · July 13, 2012 at 3:50 AM

The only sweetener I use is a little xylitol, and to me everything has tasted sweeter anyway since going primal/paleo. I feel that what desensitized people to sweets is the constant sugary drinks most people have. Since giving up soda, even the... (more)

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by 4413 · about 10 hours ago

Just got some fasting labs back. My fasting bg and insulin were way too high a month ago so we retested to make sure I don't have "pre-diabetic" condition, and/or Insulin Resistance, and/or Leptin resistance There's improvement in glucose and... (more)

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Patrick_13 0 · June 28, 2012 at 1:55 AM

First of all, congratulations on significantly lowering your fasting glucose and insulin levels. It seems that you're making a lot of good dietary choices in order to see those improvements. Dr. Rosedale (drrosedale.com), who I respect a great... (more)

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by 161 · about 10 hours ago

I saw the other similar topics, but while they provide some solutions, i didn't see many explanations in them. I have been paleo for two months and already lost one sixth of my weight. I have also been doing Leptin Reset for around three... (more)

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Don_1 0 · June 22, 2012 at 1:49 AM

You're putting too much faith in labels such as "leptin reset" and "adrenal fatigue". We are very complex and adaptable. Changes in your diet may be helpful, but the concepts you discuss are, at best, vastly simplistic. Either up your carbs, or... (more)

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by 235 · about 10 hours ago

Why is it that the only time I wake up hungry is when I have a big, late night meal? I rarely do that any more since starting paleo so I usually don't eat until hunger kicks in about 11 or 12ish. I thought I was leptin sensitive, as sleep, body... (more)

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August 0 · June 21, 2012 at 3:21 PM

I think you are normal. The modern obsession with breakfast isn't normal, and is largely a phenomenon brought about by the cereal industry. A ridiculous amount of money is spent selling breakfast foods and making it breakfast sound like a... (more)

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by 6229 · about 10 hours ago

Dr. Rosedale wrote a lot on MDA on telomere issues. I thinks he gives a pretty convincing argument that we need to wait for more accuracy, precision, and research before really using this in everyday practice. An snippet of a very long and... (more)

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gydle 0 · June 20, 2012 at 5:33 AM

I was intrigued by your post, thinking "well, you'd have to do some pretty gnarly genetic engineering to lengthen peoples' telomeres" and came across this quote by Stanford researchers in an article in PNAS: "In order for a cell to become... (more)

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by 1670 · about 10 hours ago

I just read this article by dr. Jack Kruse on LR and I'm not sure if I have this. I'm not overweight and I don't crave foods, but I do fast and eat 2 meals a day and when I get to the second one my body just doesn't say stop. If I force myself to... (more)

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Matthew_Caton 0 · May 27, 2012 at 4:55 PM

If you are not overweight, and you are not gaining weight, then you definitely are not leptin resistant. It's good to have one big meal a day. If you are worried about overeating then focus on eating high protein in the second meal, and just eat... (more)

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by 135 · about 10 hours ago

I've read Metabolic Reset: A Binge and Purge Manifesto, I know a very interesting title. I find the book extremely intriguing. It combines 3 things that I find integral to losing fat and preserving and building lean muscle. That being High Fat,... (more)

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Eugenia 0 · May 21, 2012 at 5:22 AM

I personally do not have faith in your Sunday regimen. If you eat gluten, and you're gluten-intolerant as 7/10 people on this world are (according to new studies), then you can undo a lot of good progress your body made during the week. According... (more)

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by 6418 · about 10 hours ago

Read it and consider: http://jackkruse.com/the-holy-trinity-ct-4/ Are you open to trying The Quilt's life plan? "A VLCer will always look average, but will a decent lifespans but they will never see optimal either. What is the name of my... (more)

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none 0 · February 28, 2012 at 1:54 AM

Drinks malbec from a box, sits in a tub full of ice, loads up on Tim Ferris and catches up on Robin Sharma tweets, stands back in amazment at the truth that unfolds!!! Shall I genuflect? Cross myself? Anoint myself in the waters of Lake... (more)

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by 15003 · about 10 hours ago

I am a real fan of Stephan Guyenet and Chris Kresser, but try as I might, I am struggling with the idea that a low-reward diet "reduces the fat set point." Now, I have no problems with the idea that a low-reward diet results in weight loss. And... (more)

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J__Stanton___gnolls_org 0 · February 13, 2012 at 10:15 AM

A "set point" is just a homeostasis we don't understand yet. For instance, there's no such thing as a "fat thermostat" in our bodies that we could turn up or down if we could just find the dial. There are trillions of cells in a human body - each... (more)

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by 45 · about 10 hours ago

According to much of the advice I've read surrounding leptin, the leangains approach is not very healthy. Skipping breakfast, eating at night, etc. I've tried each of them and leangains works much better for me. I'm just not very hungry in the... (more)

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Jeff__1 0 · January 19, 2012 at 11:45 PM

The leptin 'rules' are meant to reset sensitivity, as mentioned above. As someone who is leptin sensitive, I still follow the 'rules' for the most part and it really works well. I also include some IF as well as fasted workouts however. Eating... (more)

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by 15226 · about 10 hours ago

What is leptin's relationship to PEPCK? Does it stimulate or suppress it? Would love to hear thoughts on this from the sciencey types on here. edit: I think it's probably got to increase PEPCK... the second study measured a short term leptin... (more)

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akman 0 · July 03, 2012 at 9:12 PM

The Quilt is so far ahead of his time it's not funny. His year old posts are just starting to make sense. From today at http://medicalxpress.com/news/2012-07-discovery-cellular-pathways-converge-food.html : Now, researchers at Beth Israel... (more)

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by 2565 · about 10 hours ago

I recently watched a video that gave me many of the answers I've been looking for for a long time about what the dysbiosis I have in my gut is doing to the rest of my body. I also learned in this video that lipopolysaccharides (LPS) from bad... (more)

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Paul_Whiteley 0 · November 27, 2011 at 2:42 PM

Lots of perhap-es on the possible role of gut bacteria in obesity: http://questioning-answers.blogspot.com/2011/06/obesity-gut-bacteria-and-wall-e.html and http://gutness-gracious-me.blogspot.com/2011/11/gut-bacteria-pesticides-and-obesity.html (more)

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by 691 · about 10 hours ago

How to increase your growth hormone naturally? Our Paleo ancestor didn't have the use of isolated amino acids, BCAAs or melatonin to pulse his growth hormone. Most of the proven techniques today to release growth hormone naturally where done by... (more)

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Dorado_Galore 0 · November 21, 2011 at 10:12 PM

Exercise: Lift weights. Do exercises that simultaneously work a lot of major muscle groups. Sprint (on foot or bike, or in pool). Diet: Growth hormone levels increase markedly when insulin levels are low. Chiefly carbs are responsible for... (more)

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by 10 · about 10 hours ago

Hi! I have been doing Dr. Kruse's Leptin RX for about a week and a half now and LOVE it! The way it takes away hunger and cravings is a dream come true for me! Thank you Dr. Kruse! My question is about the BAB (which I LOVE!)... A couple other... (more)

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by 121 · about 10 hours ago

Jack Kruse: http://jackkruse.com/my-leptin-prescription/ (This is intended for 6-8 weeks or until leptin sensitive and a paleo diet post reset.) Ron Rosedale's website: http://drrosedale.com/healthplan.htm (I included Rosedale's b/c his was... (more)

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Andre_Chimene 0 · November 07, 2011 at 6:59 AM

Melissa, I love you and your blog, I am a fan...but Rosedale is not saying fish and chicken are healthier than beef or lamb. He is saying in the first 3 weeks, to become a more efficient ketone burner, limit SAT fat till you are on the beam. Then,... (more)

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by 253 · about 10 hours ago

First, a little background. I'm a pretty fit person, 24 yrs old, 6' tall 185 lbs I don't know exactly what my body fat is but I would guess somewhere in the 8-12% range. My problem is trying to use my diet to maximize energy levels. Due to my job... (more)

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Jamie_2 0 · November 05, 2011 at 1:03 PM

I know that I've read that Chris Masterjohn (the daily lipid blog) has stated that carbs before bed help him sleep. There's also a book called "Lights Out" that I believe recommends a spoonful of raw honey before bed to help with sleep. I WISH I... (more)

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by 3180 · about 10 hours ago

Since digestion begins in the mouth, and since there are leptin receptors on the tongue, would there be any benefit to digestion, leptin sensitivity, or other processes if the food is chewed extremely well? My whole life, I have 'wolfed' down my... (more)

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Nance 0 · November 04, 2011 at 7:35 PM

Yeah, I was always told not to eat so fast and I grew up to be a binge eater. So I guess they were right and I start every meal with a salad now to introduce the concept of chewing. I also avoid the most tender cuts of meat, but that's about... (more)

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by 8979 · about 10 hours ago

Paleo2.0 brought this up as a comment in another question. Is everything that Dr. Kruse has to say about leptin wrong? What has Dr. Kruse said that is correct? Citations would be helpful for many reading here.

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grace 0 · November 10, 2011 at 3:44 AM

Loon, thank you for your critical comments and this thread. Kruse asks questions... and I enjoy all the questions. I love all of our paleo gurus because they each bring unique backgrounds, varied frameworks (high carb v. low carb v.... (more)

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