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Leptin Resistance Questions

Leptin Resistance

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by 0 · May 18, 2014 at 10:27 AM

I began my paleo diet and bio hacking adventure about 18 months ago, but feel I have hit a brick wall and need some help to better understand my labs and situation. I’m hoping that someone might be able give me some deeper insights on reactive... (more)

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by 10 · August 15, 2013 at 11:25 AM

Hi. I have recently seen my leptin resistance go away as my appetite has normalised (first time in my life). I'm really enjoying being free from the constant hunger and worry about food. What I wanted to know is if anyone knows how closely... (more)

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Albert83BCN 0 · August 15, 2013 at 11:25 AM

As far as I know (no doc here, just an educated layperson, based on Dr Kruse ideas and some others), it seems that leptin resistance precedes insulin resistance. Leptin receptors at the hypothalamuns account for the body status of energy. If this... (more)

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by 7249 · August 26, 2013 at 01:22 PM

I am currently reading "Fat Chance" by Dr. Robert Lustig and he talks about leptin resistance and its role in obesity. Leptin, produced in fat cells suppresses appetite and speads metabolism and energy expenditure, yet in obese individuals, they... (more)

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EnglishRose 0 · August 12, 2013 at 08:16 AM

I have never been able to do due to carb/sugar addiction as it just led to a binge so I would first advise make sure you have changed how you eat and adapted. However now that I have changed I have been finding some days I can miss a meal (and I... (more)

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by 2423 · November 21, 2012 at 11:38 PM

Is Stephan Guyenet correct in this regard? (Refer to: http://wholehealthsource.blogspot.com/2012/11/why-do-we-eat-neurobiological.html) Something I've noticed over the years is that when you make an animal gain fat by giving it a fattening... (more)

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borofergie 0 · September 07, 2013 at 12:44 AM

As a low-carber, I find that I can easily put a few pounds on over the holidays (according to the scales), but I think that they're usually just due to me refilling my liver glycogen stores. It can usually rempty it easily enough.

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by 1672 · May 27, 2012 at 04:55 PM

I just read this article by dr. Jack Kruse on LR and I'm not sure if I have this. I'm not overweight and I don't crave foods, but I do fast and eat 2 meals a day and when I get to the second one my body just doesn't say stop. If I force myself to... (more)

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Matthew_Caton 0 · May 27, 2012 at 04:55 PM

If you are not overweight, and you are not gaining weight, then you definitely are not leptin resistant. It's good to have one big meal a day. If you are worried about overeating then focus on eating high protein in the second meal, and just eat... (more)

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by 2565 · May 18, 2012 at 06:22 AM

I've heard a lot of talk about how important balancing our neurotransmitters is, and the ones that are mentioned are usually gaba, serotonin, acetylcholine, etc. But I hardly ever hear about dopamine. Recently I've been doing some research on it... (more)

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interrobung 0 · May 04, 2012 at 06:18 AM

Your last paragraph sums up much of the belief of the human biochemically-savvy paleo populace, as I understand it, with some qualifiers. It is certainly the case that the leptin resistance we associate with obesity could have a role in decreased... (more)

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by 5624 · February 07, 2012 at 12:13 AM

On one of the Paleo Solution podcasts Mat LaLonde revealed that he does a protein fast in the mornings. Rather than fasting all together he has a can of coconut milk upon waking. He says that if you eat a little fat but refrain from eating protein... (more)

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Kirk_1 0 · February 07, 2012 at 12:13 AM

I have been practicing both types of fasts for several months. Usually it's for 16 hours, but sometimes 14 or 15 and, more rarely, 17. I find the true fasts more stressful, especially starting around the 14th hour. The use of coconut oil in my... (more)

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by 305 · January 27, 2012 at 02:29 PM

Hey there fellow hackers! I am writing a research paper for my nutrient metabolism class on "high fructose consumption and leptin resistance". Could you all point me to some scholarly articles or "original" studies dealing with the subject?... (more)

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cliff_1 0 · January 26, 2012 at 02:38 PM

The only models that have shown leptin resistance with fructose are diets that contain 60% pure fructose, an amount that is basically impossible to consume in a normal diet. It hasn't really been shown in human diets either as far as I can... (more)

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by 248 · January 04, 2012 at 11:30 PM

I know many tried the Leptin Reset protocol trying to be Leptin-Sensitive. But, why, do one need to be Leptin Sensitive? Is there a real scientific theory behind the claim that Leptin-Sensitive is more beneficial to Leptin-Resistant? What is the... (more)

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dzone 0 · January 04, 2012 at 04:01 PM

http://www.amazon.com/Mastering-Leptin-Permanent-Weight-Optimum/dp/1933927259/ref=sr_1_1?s=books&ie=UTF8&qid=1325692857&sr=1-1 Mastering Leptin by Byron Richards would be a great resource to answer your question. (more)

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by 2565 · November 29, 2011 at 11:25 PM

My question has to do with someone who develops leptin resistance. It's been said that one way to tell if you are leptin resistant is to look in the mirror because you'll have gained significant body fat. But isn't it also true that leptin... (more)

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Vivalapaleo 0 · November 29, 2011 at 11:25 PM

This is really interesting because part of the leptin reset is to do Hiit training - but will hiit training or even weight training drain your adrenals even more if you are past leptin and have Adrenal fatigue?? Given that weight training... (more)

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by 205 · October 05, 2011 at 03:34 AM

Hi! I am a 26 year old female, 157cm tall + weigh 147 pounds (68kg). I have been Paleo for 10 weeks now with the primary goal being fat loss. I have eliminated all sugar, grains and dairy. My daily diet usually looks like this: MEAL 1 - 150g... (more)

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Namby_Pamby 0 · October 05, 2011 at 03:24 AM

That's 400g of solid meat you're eating there in a day. Nothing wrong with that but don't you want some variety? How about some bone broth and a big ass salad with raw vegetables (not steamed). Bone broth definitely breaks the routine of eating... (more)

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by 8890 · December 21, 2011 at 02:00 AM

Rosedale, Kruse and Richards all have theories/recommendations for reducing leptin resistance. What are the differences between these three methods and the advantages or disadvantages of a particular method? Feel free to supply clinical data... (more)

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Anonymous_Chump 0 · December 21, 2011 at 02:00 AM

This fella speaks of leptin, too. Anyone know of his work?

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by 5624 · September 30, 2011 at 05:37 PM

Let's say that an individual decides to implement the Paleo diet and was not leptin resistant prior. However, like most who begin paleo, their calories decrease, they go VLC and still continue or begin a high intensity training program several... (more)

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Nance 0 · September 30, 2011 at 05:37 PM

When I tried the LR protocol, my cravings were so intense I was climbing the walls and I only lasted 5 days then binged for another 4. However, once I regained my serenity I tried a partial approach where I have a protein/fat breakfast and eat my... (more)

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by 570 · October 27, 2011 at 11:23 PM

Been Paleo for over a year and feeling good. Have been focusing on exercise (5 primal movements) for about 2 months now and been happy with the results. I'm 5'11, 165-170 (haven't weighed myself for about a month) and look pretty good except... (more)

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anon_3 0 · October 27, 2011 at 11:23 PM

I would look at blood type. Refine/weed out foods. Not sure about LR myself... I do IF and am pretty attatched to it but have gotten in to more of a Joel Marion/Jon Benson type weekly reset simply from eating more carbs one day a week. I wake... (more)

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by 39204 · August 13, 2011 at 06:32 AM

As a preface, let me confess that in spite of the fact that people are talking about leptin everywhere I go on the internet, I have spent zero time looking into it (beyond initially finding a simple definition) until this morning. I've always... (more)

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CaveDad 0 · August 11, 2011 at 08:07 PM

I hate to answer a question with a question, but I'll do it anyhow. Could one simplify this concept to state that consumption of fructose, via an increase in insulin and/or a decrease in leptin cause obesity? (Due to a genetic adaptation... (more)

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by 13928 · July 24, 2013 at 12:24 PM

From the book "Mastering Leptin" come these five rules for losing weight and/or managing other hormonal issues: Rule 1: Never eat after dinner. Allow eleven to twelve hours between dinner and breakfast. Never go to bed on a full stomach.... (more)

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Vern 0 · August 04, 2011 at 07:48 PM

I think any advice that contains absolutes is bad. Always and Nevers are a terrible way to live. It's failure in practice. Not everything works for every person, and every person's body. Go fly a kite, Byron J. Richards (more)

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by 1025 · August 05, 2011 at 05:33 PM

I’ll start by saying that I really enjoy reading and participating in this site and I particularly am in awe of its excellent features such as badges, reputation, upvotes, comments, upvotes on comments, etc. I don’t know if this is unique or par... (more)

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Stabby 0 · August 05, 2011 at 02:26 AM

(warning, long rambling post, might be repetitive and have errors) The way to resolve the problem of people who have good metabolic health telling those who don't what they can and can't do is resolved by proportioning one's beliefs to the... (more)

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by 205 · July 23, 2011 at 03:07 PM

Though I eat strict paleo I cannot get the weight to move. I've been reading about adrenal fatigue, leptin-resistance, hormonal imbalances etc. and often come across recommedations to supplement with pregenenolone to get the hormonnal systems back... (more)

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Kelly_3 0 · July 23, 2011 at 01:50 PM

Laura, have you had any testing done to indicate Adrenal fatigue or hormonal imbalances? Can you give us a bit of info on your diet perhaps thats a better place to start rather than going for meds.....