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Longevity Questions

Longevity

Paleo Questions

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by 24523 · September 16, 2014 at 7:21 PM

Sex is a favored way to make babies. There is some interplay between reproduction, repair, and longetivity. In fact, worms live much longer when food is scarce and they put a hold on reproducing. And typically, what applies to worms applies... (more)

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Bread_Eating_Beelzebub 0 · April 19, 2011 at 2:15 AM

I think you are going to find actual sex has less of an effect than the levels of sex hormones because human culture is so weird. There is ample evidence that men with very high testosterone levels die earlier, though there are some confounding... (more)

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by 39821 · September 16, 2014 at 7:18 PM

I've been camped out around 12% for a while and through experimentation have found what choices make me a little leaner or a little less lean, so I'm confident I could camp out at 10% or so, but that decision would be based on narcissism, not... (more)

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sherpamelissa 0 · January 20, 2011 at 1:12 AM

I don't know about optimal body fat for health and longevity, but I know my goal was to get under 25% and now that I've been eating Paleo for a few months I'm hovering around 20-22%. It is absolutely perfect FOR ME. I like the way my body looks... (more)

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by 641 · September 16, 2014 at 7:28 PM

I was reminded the other day about the section in GCBC regarding Cynthia Kenyon's research linking carbohydrates and longevity (that is, at least for C. elegans). Adding glucose to C. elegans' diet significantly reduced its lifespan via an... (more)

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Ron_Rosedale_M_D_ 0 · August 28, 2011 at 1:16 PM

Aging, and health, are not related to caloric restriction per se. It is related to nutrient sensing hormones and pathways that caloric restriction effects that in turn greatly influences genetic expression towards a longevity phenotype. The same... (more)

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by 588 · September 16, 2014 at 7:15 PM

In Michael Rose's talk (about his Methuselah flies and what they mean for longevity) at the recent Immortality Institute conference in Brussels, he talked about the three diet regimes that humans have lived under: Hunter Gatherer (2.5M years(?),... (more)

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Eva 0 · October 21, 2010 at 7:01 AM

The reason I don't quite buy that theory is that older people who have eaten healthy kinda paleo style all their life do not get sick right away if they eat neolithic. THey might experience a period of adaptation, sure, but they don't get... (more)

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by 603 · September 16, 2014 at 7:42 PM

Lithium (Li) is a trace mineral, used in the treatment of bipolar disorder at doses hundreds of times higher than that from diet. The main dietary sources are vegetables and grains, followed by dairy. The concentration in water varies widely:... (more)

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tdgor 0 · April 09, 2012 at 3:04 PM

Here's a fun fact: lithium citrate was one of the original ingredients of 7Up (much like the cocaine in Cola-Cola). All American beverage makers were required to remove lithium from their products in 1948. A less fun fact: lithium causes weight... (more)

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by 15400 · September 16, 2014 at 7:47 PM

I know this question is kind of odd, but... I really want to know and I hope somebody here on Paleohacks knows the answer. I always wanted to know what was Creme Puff's diet, but never was able to obtain a verifiable source. I know she ate... (more)

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Paul_Jaminet 0 · August 02, 2012 at 11:27 AM

Whether or not it's Paleo, it's consistent with other evidence that high-fat low-protein moderate-carb is good for longevity.

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by 2255 · September 16, 2014 at 7:42 PM

Dr Leila Denmark has recently died at the age of 114. A remarkable woman she was still working as a pediatrician at the age of 103. http://en.wikipedia.org/wiki/Leila_Denmark Apparently she refused cake at her 110th birthday party claiming she... (more)

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jake_7 0 · April 05, 2012 at 5:54 PM

i think a big aspect people often forget about when it comes to longevity is mental health and social health. diet obviously plays a role but its not the be all and end all in living for a long time.

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by 1054 · September 16, 2014 at 7:33 PM

Professor Cynthia Kenyon, whom many experts believe should win the Nobel Prize for her research into ageing, has discovered that the carbohydrates we eat ??? from bananas and potatoes to bread, pasta, biscuits and cakes ??? directly affect two key... (more)

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Bread_Eating_Beelzebub 0 · November 20, 2011 at 6:54 PM

There are no real long-term studies on this, but thankfully there are dozens of Arctic tribes that ate a low-carb high-fat diet. We have the Inuit, Saami, Athabaskans, Eveny, Nenets, Itelmen, and Koryak peoples for example. It's a diverse... (more)

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by 2199 · September 16, 2014 at 7:52 PM

What are the main differences in how someone processes glucose from the diet vs gluconeogenesis? Paul Jaminet, a seriously smart cookie and charming guy, writes we need a certain number of grams of glucose a day and can create it through... (more)

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Jeff__1 0 · August 17, 2012 at 10:13 PM

In addition to what Drs Kruse and Jaminet said, I think an important distinction is that gluconeogenesis is regulated by internal feedback mechanisms. Safe starches are regulated by who puts the food on our plate and how big of a portion it is. (more)

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by 128 · September 16, 2014 at 7:33 PM

I am into living the healthiest life I can, while I'm here. If it prolongs my life, so be it...but that isn't my goal. I am looking for intense quality not quantity. I can't wrap my mind around why people want to live for as long as possible,... (more)

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sage_ 0 · November 19, 2011 at 9:35 AM

i want a flying car and to have sex with an extraterrestrial.

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by 155 · September 16, 2014 at 7:52 PM

I have watched a very interested program by the BBC (link below), it covers various methods of sub-calorific and intermittent starvation, fasting, IGF1 and aging, also the effect on cancer and heart disease. As ever a very entertaining and... (more)

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dsync 0 · September 04, 2012 at 4:08 PM

Some biases info: I am an IF follower at an 18 off / 6 on ratio. I feel compelled however to note a few things. IF at caloric surplus is completely different from IF at maint, which is completely different from IF at deficit and all of this is... (more)

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by 571 · September 16, 2014 at 7:34 PM

While thinking along the lines of the human species as a whole, doesn't it make sense that death of a person after say... 30-35 years of age (after raising offspring) would be optimal? That a shorter lifespan would be optimal for our species as a... (more)

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Chappy 0 · November 30, 2011 at 9:19 AM

Genes aren't selected for the good of the species as a whole. It is irrelevant whether a shorter lifespan would be optimal for the species. A total lack of violent tendencies towards other humans would surely be optimal for the species as a... (more)

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by 593 · September 16, 2014 at 7:56 PM

I stumbled across this article on Facebook via one of the relatives of this Thousand Oaks, CA woman who just turned 107. Imagine my paleo delight when I read the phrase (bolded below) about bacon grease. Haha. Does anyone else stumble across these... (more)

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Dave_S_ 0 · October 15, 2012 at 7:23 PM

My friends aunt is in her 90's. For 30 years she has a hot dog and an orange soda from the vendor near her apartment three times a week for lunch. She eats candy and chocolates and generally very typical SAD food. Probably worse than most. Some... (more)

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by 695 · September 16, 2014 at 8:09 PM

" Reduced glucose availability promotes formation of reactive oxygen species (ROS), induces catalase activity, and increases oxidative stress resistance and survival rates, altogether providing direct evidence for a hitherto hypothetical concept... (more)

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Warren_Dew 0 · June 06, 2013 at 10:26 PM

Thanks - interesting article. It's to be noted that the worms for which the lifespan extension was suppressed were bathed in rather high levels of antioxidants - a 5 millimolar concentration - as opposed to the normal blood plasma concentration... (more)

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by 3125 · September 16, 2014 at 7:35 PM

Can eating paleo modify our epi genome making us younger as we get older? in worm studies, caloric restriction reduces insulin to increase lifespan. In Paleo man carbohydrates and not calories are restricted but because the hemoglobin A1c levels... (more)

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thhq 0 · December 21, 2011 at 12:34 PM

What we eat and do in this lifetime will change our personal outcomes, but I'm dubious of an effect on personal genetics, which would affect our descendants rather than us. I agree with anonymous that we can increase our longevity most by taking... (more)

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by 79 · September 16, 2014 at 7:31 PM

I'm seeing a lot of advocating for "eliminate, then reintroduce" science in the paleosphere lately. While I think that it is a good approach for determining what foods a person has a sensitivity too, I think it is a terrible method for finding the... (more)

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Ambimorph 0 · October 04, 2011 at 10:11 PM

I'm of two minds about eating to tolerance. I think it's a good point that just because eating some food doesn't manifest in immediate bad symptoms is not evidence that it is safe. If you'll forgive my imprecision (I can't cross-check right... (more)

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by 2933 · September 16, 2014 at 7:29 PM

Living the paleo life will hopefully put my on track for a long healthy life, which got me thinking - taking everything into account... what could that realistically be? Starting with genetics: looking at my grandparents. One grandmother died aged... (more)

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Jeff__1 0 · September 09, 2011 at 3:18 PM

I think quality of life is much more important than shear number of years lived. By eating a clean paleo diet it allows us to make better use of each day due to lack of blood sugar swings and overall better moods. A person who lives a good life,... (more)

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by 1078 · September 16, 2014 at 7:36 PM

Loreen Dinwiddie is allegedly a 108-year-old vegan who has been vegan since 1922. Is she lying, lucky, or is veganism not that bad? How can a body function after 90 years of guaranteed B-12 and DHA deficiencies, not to mention probable... (more)

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Aravindan_Balasubramanian 0 · January 16, 2012 at 2:36 PM

There's a lot more to health than nutrition Stress management Sleep Genetic / Epigenetic considerations Regarding DHA deficiencies, it isn't a foregone conclusion that vegans or vegetarians in general will be deficient - perhaps not... (more)

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by 2199 · September 16, 2014 at 7:50 PM

What resources or thought leaders do you reccomend to learn about epigenetics, nutrition for longevity and nutrigenomics?

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Mscott 0 · July 27, 2012 at 3:55 AM

For nutrition and longevity the book Mechanisms of Dietary Restriction in Aging and Disease is pretty good. That link is to the E-book, but only about 1/4 of the book is available. I don't really agree with everything in it, but it's a pretty... (more)

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by 699 · September 16, 2014 at 7:13 PM

I have heard it from a couple people in the paleo community that longevity is tied to muscle mass. Can anyone expand on this? If this is the case I might try to bulk up.

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jm054 0 · May 24, 2010 at 12:47 AM

http://www.marksdailyapple.com/organ-reserve-muscle-mass-aging/ http://blog.modernpaleo.com/2010/03/muscle-mass-for-health-and-longevity.html (more)

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by 11478 · September 16, 2014 at 7:18 PM

Numerous animal studies have shown that restricting calories promotes a longer lifespan. But chronic caloric restriction lowers your muscle mass, and increased muscle mass is also tied to longevity (discussed in a previous thread). So if I want to... (more)

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Adam_Crafter 0 · January 22, 2011 at 11:25 PM

http://www.pnas.org/content/100/10/6216.abstract was the major paper that broke the news that Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie... (more)

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by 45 · September 16, 2014 at 7:14 PM

What are the benefits of Fasting? and what should one know before doing it?

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TaviLola 0 · July 30, 2010 at 12:20 PM

I suggest reading Eat Stop Eat by Brad Pilon, he goes over the science of fasting for fat-reduction quite thoroughly. Personally I find it to be VERY effective. I don't count calories or carbs, but I eat in three hour windows and fast 24 hours (so... (more)

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by 11478 · September 16, 2014 at 7:14 PM

A previous PaleoHacks thread ties health and longevity to muscle mass, i.e. more muscle mass means a longer and healthier life. Brad Pilon and others have said that there is a genetic lean muscle mass "set point" that determines how much skeletal... (more)

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Ryan_1 0 · July 07, 2010 at 4:19 AM

The answer is if you are an ectomorph you already carry the gene to live a long life (ACE II). If you are able to pack on muscle easily you do not carry this gene and instead have ACE DD. "One other factor that likely separates the ???ripped???,... (more)

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by 2052 · September 16, 2014 at 7:16 PM

http://www.dailymail.co.uk/health/article-1323758/Can-cutting-Carbohydrates-diet-make-live-longer.html ???I???ve cut out all starch such as potatoes, noodles, rice, bread and pasta. Instead I have salads, but no sweet dressing, lots of... (more)

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truth_in_health 0 · October 27, 2010 at 3:41 AM

Dr Rosedale was one of the first, if not the first to speak widely around the world on this topic. Everyone should read ???Insulin and its Metabolic Effects???, a transcript of one of his popular talks many years ago that is posted all over the... (more)

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by 38 · September 16, 2014 at 7:51 PM

I saw this article and was curious the reaction here. Seemed to raise some good points... http://www.paleopharm.com/my-beef-with-the-paleo-diet-2-0/ The Central Dogma of Paleolithic diet 2.0 theory ??? that our Stone Age DNA is ill suited... (more)

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Alec_3 0 · August 09, 2012 at 3:59 AM

I'm sorry but I've read books that were't as long as that question.