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Brain Fog after starting a probiotic

by 5 · December 14, 2012 at 08:29 PM

This more of a brain-fog question rather than a paleo question, but I have seen several questions by people dealing with brain fog here so I though that I'd give it a try.

Here is a brief story, I am a healthy 28 year old Male, 6'4" 195lb. About 5 months ago, I was prescribed an antibiotic clindamycin for a skin infection and since then I have been dealing with digestive issues. Abdominal pains, soft stools and occasional diarrhea. I got tested for cdiff 4 times (negative each time) and other infections also came back negative, I have also had blood work which came back completely normal. So, I am assuming that this is a simply a dysbiosis issue. I have been taking probiotics for about 4 months and I have seen some improvement. For the first three months I mostly tried L. Acidophilus (Pearls), B. Infantis (Align) and S. Boulardi (Florastor/Jarrows). About 5 weeks ago I added Jarrows EPS which contains ( L. rhamnosus, L. helveticus, Bifidobacteria Longum, L. Casei, L. Plantarum, Lactococcus Lactis, B. Breve, Pediococcus acidilactici, 5Billion CFU total). At the time, I was also on S. Boulardi (Jarrows). After starting Jarrows EPS, I noticed that I would occasionally have a dazed/brain-foggish feeling along with a slight fatigue. I continued the probiotics for about 2 weeks and then stopped both of them completely. Initially I assumed that this was a die-off/herx reaction but now it has been 3 weeks after stopping the probiotics but I still get the brain fog feeling. I am positive that these brain-fog issues started after starting the probiotic. Nothing else in my diet changed during the period. After getting the brain fog, my GI system does not seem to have changed much.

I had CBC-diff and thyroid testing which was completely normal. My fasting blood sugar level was also normal. I am also drinking a lot of water. I am thinking of getting my B12, B6, Folic Acid, levels tested, but I doubt that these could have dropped off suddenly. My GI told me to wait for a while and see if there is any improvement. Any ideas on what could this be and how should I deal with this. Initially I thought that this was just a matter of time and it would go away on its own, but now about three weeks after stopping the probiotic, I am loosing hope. Is it possible that my antibiotic ravaged gut was ripe for SIBO and the probiotic tipped it over?

Thanks, arbguy

UPDATE 08 Sept Well, the single strain probiotic does not seem to have helped. If only the brain-fog seems to have increased slightly. Also, if I exercise/work out, I seem to have a more intense fog the next day. The duration is making me convinced that this is not a die-off, but something new - SIBO/Candida. I will be visiting my GI this week and I am also planning to see a neurologist. The brain-fog also seems to be increasing my stress/anxiety which is probably feeding it back.

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6 Replies

F5a0ddffcf9ef5beca864050f090a790
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15380 · August 28, 2012 at 07:17 AM

I don't have an answer, but I can tell you what probiotics worked for me:

  1. They were from the refrigerated section
  2. They were one or two strain only and I doubled/tripled the dosage
  3. When I tried probiotics with more than one/two strain, I did not notice any effect
  4. I buy pro-biotics that have only one ingredient - the bacteria itself

I think your probiotics may have some additives (they put all kinds of things as fillers) and way too many strain.

Oh, one more thing - it may help you - once I overdosed probiotics (like really really overdosed - I had more than tripled them, they were different strains, and had a huge amount of probiotic foods and also had some beet kvass on the same day). I had a headache, a brain fog and something else - I don't remember - on that day.

After that I did not take probiotics for a couple of days and then restarted decreasing the amount and one strain at a time only. I was fine after a week or so.

86891046d0b097a1747ad8a8d479b05b
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10 · August 28, 2012 at 01:24 AM

I had some similar brain-fog and fatigue issues after an infection/antibiotic.

Finally a GI doc diagnosed me with fructose/fructan malabsorbtion (he said about 1% chance after an infection/antibiotics to get it).

It can cause depression by messing with tryptophan so it doesn't go up to make seratonin, I guess (I'm not expert but that's what I understood from what he said.)

The test consists of 4 rounds of fasting and drinking a (glucose/fructose/fructan/lactose) solution and breathing into a balloon every 15-30 min for 2-3 hours.

The treatment is called a low-fodmaps diet. My belching and upset stomach went away about a month into the diet. He said the condition is self-limiting, but could last months to years before gradually getting better.

Not saying that's for sure what you have, but could seek out those tests or experiment with the diet to see if it helps.

42108a40e7cac857a3aecd9fb143ca8e
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0 · December 14, 2012 at 08:29 PM

Balls in your mouth

3ad2bfe68a8f8766f50792e46c01651e
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-2 · August 29, 2012 at 11:48 AM

The Dangers of Probiotics: invasive infection, antibiotic resistance There are two possible dangers of probiotics: invasive infection, resistance to antibiotics

Invasive Infection occurs by taking probiotics which then translocate into the blood stream. Probiotics, according to the WHO are "live microorganisms". The reported cases where invasive infection occurs after taking probiotics are low but they exist:

detoxification

F5a0ddffcf9ef5beca864050f090a790
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15380 · August 28, 2012 at 07:12 AM

I don't have an answer, but I can tell you what probiotics worked for me:

  1. They were from the refrigerated section
  2. They were one or two strands only and I doubled/tripled the dosage
  3. When I tried probiotics with more than one/two strands, I did not notice any effect
  4. I buy pro-biotics that have only one ingredient - the bacteria itself

I think your probiotics may have some additives (they put all kinds of things as fillers) and way too many strands.

65333605eb0e62ccdb9ffaac00727bc6
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162 · August 27, 2012 at 11:51 PM

Are you taking a complete amino acid? It's made a huge difference for me :-)

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