Many years ago I heard a piece on the radio that mentioned waitresses and others who stand for work can be at higher risk for heart disease, varicose veins, and atherosclerosis. I was a barista at the time I heard the piece on the radio so I tried not to think about it, head in the sand style.
But today I found this http://www.arpapress.com/Volumes/Vol8Issue1/IJRRAS_8_1_03.pdf while wondering about my aching back and sore ankle and am thinking about it more. This doesn't lead me to believe that sitting on one's butt all day is the best idea either, but it seems unnatural to be chained to any particular posture for an extended period of time. I've spent almost all of my adult working life standing, and now have a standing desk at home, but I'm thinking that I might need change it up a bit, and do more reclining.
*Edit:*It just occurred to me that there are certainly confounding lifestyle variables here, since the majority of standing jobs have historically been lower paid positions. I know standing desks in higher paid office jobs are newish, but has anyone seen data yet on the impact of health with white collar workers other than the "increased activity levels of standing compared to sitting 8-10 hours per day improves fitness" type reports.