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This is what Kurt Harris says in the comments for Melissa's recent article The many-venomed earth :

Hi Chris

I must respond to your comment as it is so spot-on. I am starting to think the core paleo conceit of our health being ruined by eating particular things, and we can all be fixed by avoiding them, is simply wrong. Dangerously, misleadingly, wrong.

I've long ago tossed the idea that a particular macro ratio is poison, and am now starting to think that the EM2 (or EEA) is defined less by novel NADS as particular substances, and more by the gut microbiome and environmental pseudocommensals and their critical effects on our health.

I believe loss of tolerance for eating just about anything (except obvious NADS like excess LA and huge amounts of fructose) is a sign of immune dysregulation in MOST cases. It definitely is a sign of immune dysregulation to have an allergy to beef, or shellfish, or rice (very common in Japan). I disagree with Dr. Ayer's on that point. Even IBS has been recently shown to be characterized by abnormal mast cell populations in the gut- the same cells mediating airway and skin allergies.

Take the case of Wolf. Robb Wolf was not poisoned by wheat and saved by paleo. He was rather a victim of a particular disease of immune dysregulation- celiac disease - which was and is ameliorated BUT NOT CURED by a wheat free paleo diet. He must stay off gluten to stay in remission. He is not "cured". If he were he could eat wheat with impunity like I can (Yes, my tests for celiac were negative).

In the same way, someone with Crohn's disease or AS is not being poisoned by starch feeding particular bacteria in the gut, they are victims of an abnormal immune response to gut bacteria macromolecules that we are supposed to be able to - are actually evolved to - tolerate. The GAPS diet or similar, if it works for IBD, is palliative and not curative. The idea that starch or even gluten are per se NADS is wrong.

As you have discovered, one may eat any of a variety of PERFECT paleo diets and still not really be emulating the EM2, and therefore may still be or become seriously sick.

In your own case, you've palliated your Crohn's disease with diet, but still have a haywire immune system, which now has given you the disease of Lupus.

Unfortunately, it is highly unlikely that any paleo diet or guru with do anything for your Lupus, because what particular foods you eat is not the most important part of the EM2 that you are missing.

If you want to, you can email me off blog.


The auto-immune paleo diet didn't do me much good, except for the first month or 2. Since adopting some of Ray Peat's ideas, who focuses more on eating things than not eating things, I'm a lot better (I do have a long history of hypo-thyroid-like symptoms).

His fructose hate bothers me a lot though.

What are your thoughts on this? Is gluten the new safe starch? Does food avoidance equal stupidity?

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I totally disagree with his take on GAPS. That diet tries to improve one's digestion, and is not really a food avoidance diet (only in the first couple of weeks). Dr. Harris has the tendency to be a bit too confident. – Bruno Mar 25 2012 at 9:30
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I think where he was going with his comment is that a number of diet gurus are confusing their personal autoimmune responses with the healthful/unhealthfulness of certain foods. I don't think he is dissing the basis of those diets necessarily, just wanting us to get our facts straight if we are going to be shouting this stuff from the rooftops. – Happy Now Mar 25 2012 at 9:40
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The more I think about this the more I am bugged by it. In simplistic terms - if you drive a spike through your leg, yes, removing the spike doesn't heal the wound. But it's going to be nigh impossible to heal without removing the spike. – Kelly Mar 26 2012 at 18:29
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Am I the only one who thinks what Dr. Harris says are just empty words most of us already knew? Did anyone here really believe paleo cures us all? – Bruno Mar 28 2012 at 7:59
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Interesting how you have devoted a whole paleohacks question to "empty words". If what I said seems obvious to you, then you need to read it again, because you don't get it. – Kurt G Harris MD Mar 28 2012 at 16:04
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29 Answers

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Patrik gets it. Most of the rest here are simply illustrating the beliefs I find so disturbing.

Does everyone here think that you can be normal and not be able to eat beef, rice, peanuts, tomatoes, apricots, fish, crustaceans, gluten, or starch?

Does everyone think that the cause of allergies to a thing is the thing? The very definition of an allergy is that the reaction is to something that should be and usually is innocuous.

Those who think I am "bashing" the GAPS diet are totally missing the point. GAPS can be profoundly effective, like an asthmatic can stay out of the ER by avoiding cats.

Would I advocate that an asthmatic allergic to Fel d 1 antigen sleep with a cat in his bed?

Of course not. Does that mean that cats are the cause of cat allergies?

Did you know the most common food allergy in Japan is to rice? The most commonly eaten food is the one most often causing allergy.

On a pacific island some well-meaning doctors showed up a few decades ago and de-wormed the population. The rate of environmental and food allergies and asthma skyrocketed. Guess what the most common food allergy was. It was octopus, because they all ate a lot of Octopus.It was not rice or beef or pork. Octopus.

Think carefully about this. Is there a pop book on Japanese amazon that focuses on healing your gut by avoiding rice? If there were, what would that tell you?

When thinking about what is wrong with modern health and whether DOCs are caused by deviation from the EM2 (evolutionary metabolic milieu, otherwise called the environment of evolutionary adaptedness) we need to consider many things. Diet is only one.

I used to think, like Eaton and Cordain and Lindeberg and my friend Robb Wolf, that most of our deviation from the EM2 was diet. Eating the wrong things or not eating enough of the right things, sites like this one are all based on this premise. Even if it takes tweaking or hacking, or adding in IF or cold therapy or vitamins or supplements, the basic premise has been that if you keep at it you can come up with a diet that will make you optimally healthy.

I used to think so too. But now I don't.

Is this some kind of disavowal of the Archevore diet? No, I think the diet is pretty great for me and most everyone who has used it.

I still think diet matters, but I no longer see the most important NADs as likely to be particular foods to avoid.

A state where everyone needs to eat a customized, idiosyncratic paleo diet to not be sick, where there are legions of people continuously altering their diets in an attempt to get healthy, and there are many many people who eat PERFECTLY in every way that still have serious DOCs is telling us something.

It is telling us to look at other things.

My bias is now that avoiding totally novel amounts of unnatural foods like excess LA and excess fructose is important, but there are some factors that are likely to be more important.

These factors relate to the history and state of your microbiome environment throughout your life, and this in turn is the major determinant of food intolerances, allergies and the epidemic of serious diseases of immune dysregulation in western society. These are likely the major cause of many of the DOCs, more than failing to eat an idiosyncratic diet you need to learn from a book or website.

Allergies and intolerances are not caused by allergens. They are caused by an unruly, undisciplined, uneducated immune system that if often well armed but blind and operating with a hair trigger.

Anyone who is really interested should pubmed Dr. Graham Rook and read whatever he has written or edited very carefully, especially if you are sick.

And don't take any action in a half-assed fashion. Very powerful ideas are like a double rifle in .470 nitro express. Effective but very dangerous. You can hurt yourself or others if you have no idea what you are doing.

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On some Pacific island there is a popular book called Octopus Belly and a site called unoctopushacks.com where people give advice on how to avoid the evil octopus in your diet. According to unoctopushack.com user Tomnga Toga, "Unoctopus does not say avoid octopus because it's an allergen. It's says avoid it because it is not food, so it doesn't count!" – Bread-Eating Beelzebub Mar 28 2012 at 0:52
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It is not my style to be coy or cryptic like Dr. K of the K4. Seriously, this is a very powerful - actually dangerously powerful idea. It is the old friends hypothesis, a sophisticated and well-thought out subset of the older and oversimplified hygiene hypothesis. I want people to learn about this and think about it on their own. If I summarize in my admittedly pithy way in a blog post, I will have people taking it as actionable advice instantly. The ideas are too dangerous to speak about flippantly but rest assured I will have more to say in next year about this. – Kurt G Harris MD Mar 28 2012 at 1:12
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Dr. Harris... thank you for spending a good deal time time off-line thinking before spending a lot of time online expounding. Your ideas are stronger for that effort. :-) – jj Mar 28 2012 at 1:35
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Dr. Harris, are you just trying to justify a diet with donuts and pizza? Your statements seem a bit like empty words to me. You say Patrik gets it, but Patrik simply says Kurt Harris has, with his brief comment, delivered what may prove to be very deep insight into the nature of health & diet. (It may also disturb some of you too. C'est la vie.) How can you know he gets it just because he applauds you? You come over like Dr. Kruse, to be honest : lots of sensational speaking but nothing meaningful except the already known. – Bruno Mar 28 2012 at 14:08
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Can we ignore the issues for a quick second and instead focus on Kurt's vocabulary? "Venal", "Harpie", "Flippant". Okay, maybe the last one isn't that special. But as someone who enjoys a well-crafted sentence, I'm loving this. – Kamal Mar 28 2012 at 19:03
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Bruno, I did paleo because of IBS and pancreatitis. I could not handle dairy, grains, lots of vegetables, beans etc. Now I can eat whatever I like (but I don't eat crappy processed food because it tastes like ass compared to real food and it's simply not nutritious). I also got better through Ray Peat's work. All that easily digested food gave me a chance to get better, also frequent eating and more food than before overall. At first I was strict about keep starch low, now I do really well on a more starchy diet (potatoes, rice, even bread gives me no bother and I can get back to my old love affair with homemade sourdough). I think Kurt Harris is a humble crusader in the search of health. I really admire people who have the balls to keep it moving forward. It finally hit me that good nutrition shouldn't be restrictive and difficult to follow. It saddens me to see all the paleohack questions about lapses, binges cycled with pureness and strictness. That's a rollercoaster of stress and it's not good for you, physically or emotionally. Been there. Now I eat what I like, enjoy it, don't feel guilty and don't get sick. I am just looking at a thread named 'do you avoid looking at food picture while IFing'. That kind of sums paleo up for me. I understand that not everyone can get to the stage of eating pretty much anything, certainly not quickly. Btw, Ray Peat is the most interesting scientist discussing nutrition I have read. But I'm no cultist. Feel like I have to say that because I tend to get accused of following a 'guru'.

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I am starting to picture healing through food as more of a ladder than a static plan where you just continue on in the same way ad infinitum. Taking away things that trigger harm is certainly a good place to start, and you might need to live in a proverbial cave for a while to get there, but that is the beginning, not the end of the healing process. – Happy Now Mar 25 2012 at 22:40
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"It saddens me to see all the paleohack questions about lapses, binges cycled with pureness and strictness" I agree. That's no way to live. I do have to stick to a stricter eating framework because of health issues, but within that framework I try to be as flexible and joyous in my eating as possible. Stress over dietary purity does no one a bit of good. I would love it if my health someday allowed a reaquaintance with homemade sourdough. :-P – jj Mar 28 2012 at 1:29
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In my explorations, I discovered a blog called "Cheeseslave". I've been following it for a while, and recently, through the author's exploration of traditionally-prepared seeds and grains. In a way, it brings me "full circle" in my own health explorations, because it brings me back around to something close to WAPS.

I figured out about half a year ago that for me, the issue of food is more heavily related to how close to 'real' food what I'm eating is. Is it naturally fermented? Great. Is it eaten with respect to my body's own clock and sensory commentary? Great. Does it avoid over-emphasis on "replacement" foods that delve into heavy use of "alternatives" while not changing the paradigm from which I eat? Not so good.

For me, I find that anything in excess exacerbates my less-than-functional self. Staying healthy has become a conversation revolving around things I knew way back when I was a midwife (like how to feed a pregnant woman in a way that provides the best health for her and the baby, even through nausea and late-pregnancy stomach compression); through my naturopathic training (eliminating whole groups of foods just to replace them with OTHER 'imitation' foods is -not- improving health -- it's just pushing the issues off until they show up somewhere else); and through my progression into "paleo" and "primal" eating.

What does eating "primal" mean to me? It means choosing the BEST foods of the season, and eating them according to my appetite. It means learning to trust my BODY again to tell me when it's doing well, and when I need to make changes. It's about -challenging- myself to move more, do more, and avoid "societally programmed thinking" that makes me lazy about how I nourish and sustain myself and those I love. It means remembering where my food comes from, and taking pains to assure that the food that I eat is given as much chance as possible to be at peak performance itself.

I love this community, but I am pretty sure I stopped being "paleo" a year ago by the strictest standards, and I think I may have dropped off the "primal" radar recently as well, with the introduction of a few sprouted and fermented seeds that I've been experimenting with (in particular millet, which my body seems to -really- like). The point, for me, though, is that listening first to my body was a gift of the Paleo culture--it wasn't until I found this community that I found other people who had some of the same experiences that I did, and who found a real problem with the apparent solutions out there.

I'm a VERY large lady -- but I'm an ENTIRE PERSON smaller than I was when I started out on this. I didn't come on board looking for miracles -- but in a way, I found one, because, out of all of this, I found my own voice, not just where my body is concerned, but where my apparent persistence of Shamanic behaviors (which our culture now, mostly, consider to be good reasons to go get medicated), and my general approach to society were concerned. I found myself among people who, for the most part, were comfortable with someone returning to a simpler, less technologically-repressed way of interacting with our world. THAT, I think, is the gift of paleo/primal for me -- that I stopped seeing all of the technology as a filter through which my world had to pass in order to be "acceptable"... and started seeing the technology and the opinions that garner from a technological world as TOOLS -- I could use them if they worked for me, or set them aside where they massively -failed- in MY LIFE... and now I understood that I had a choice.

Whether paleo/primal is a solution for some people, I think we've developed this idea that there is some "magic" way of living that is going to solve all of our problems. No diet can do that. The best we can hope for from our food is that it nourishes us and gives us the strength and energy to use OTHER tools to become capable of everything that we want to do in our lives... and isn't that enough

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Your thoughts resonated deeply with me, Firestorm! I decided long ago that my gut would never fully heal if all I did was avoid certain foods. I believe I am now healed, only because I've made good use of pre-/probiotic foods and--like you--avoid eating too much of any one thing. I really believe the best answer is to eat the widest variety of whole foods as you heal. It's hard now to remember just how bad I felt. – Nance Mar 25 2012 at 16:19
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Yea i think many people who go on strict diets get even more sensitive so eating a wide variety of foods is really a great idea but you really need to listen to your body properly. – Natureman Mar 27 2012 at 11:49
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I find very interesting that different people, with different ideas and backgrounds, are converging towards what seems to be the most important and (until now) overlooked health component. The Human Microbiome Project is the new Human Genome Project. This is how big is seen in the area.

However, I disagree with Dr. Harris regarding the importance of diet. As I have written in some posts (and will be writing more thoroughly in following posts), nutrition is able to modulate the response, differentiation and maturation of immune cell types. Differentiation towards T-regulatory cells or T-effector cells is controlled by intracellular proteins that play a central role in metabolism. It is true that an abnormal gut microbiota since childhood in most cases is impossible to cure, but diet can make a great contribution towards partial recovery or remission of the broad range of possible symptoms. This would be mediated both directly (on immune cells) or indirectly (via adipose tissue composition, energy balance and gut bacteria composition). I think that any measure with basis on the Old Friends Hypothesis should take into account the effect of diet and use other measures (antibiotics, fecal transplants, biofilm disruptors, etc.) as tools, not as central components.

Forgot to mention that the genotype seems to be very important for the immune response to a given microorganism, being an Old Friend or not. Not only the given combination of MHC alleles, but also, there are specific SNPs in interleukin related genes which influence the inflammatory status. Interleukin genes have been selected depending on the pathogen load of the individual as well as the specific exposure. So the immune response of an individual is also shaped by pathogen history from its geographical area and ancestors. In a more global-related manner, this co-evolution with microorganisms shaped the expression of interleukin related genes. It seems that in the case of helminths and some other parasites, we have "trusted" some part of the inflammatory balance (ie. the production of some molecules with anti-inflammatory actions, like IL-10) to these organisms, upregulating some inflammatory genes. If you take out of the equation the presence of these organisms (as produced by modern hygiene practices) you are skewed towards a basal pro-inflammatory environment.

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Lucas, what's the most easily digestible (har har) academic paper on gut recovery via diet (even a case study) that you've seen? – Kamal Mar 28 2012 at 2:02
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Rodger- It used to be thought that particular gut species were what conveyed protection, but attempts to alter the flora in a way that helps have been at best mixed. Now it looks like turnover or variety of commensall and exposure to mild bacterial pathogens is what is key, and harboring particular species is what conveys protection. There are indeed big differences in gut biota between modern city folks and modern primitives, but there is no evidence that one can permanently switch your biota from one to the other once it has been well established. – Kurt G Harris MD Mar 28 2012 at 2:21
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Kamal I think the bacterial microflora reflects immune status much more than it causes it. This explains why most trials of probiotics in humans, except in particular exceptional cases, show weak effects or none. I personally expect that to remain the case. When there are beneficial effects demonstrated, they cease as soon as the probiotic is stopped. There is no good evidence you can permanently "improve" your gut flora with probiotics. – Kurt G Harris MD Mar 28 2012 at 2:33
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Kamal, Dr. Harris: I haven't seen any controlled human trial attempting to modulate or treat autoimmune diseases via diet. Most of what it is known (which is not much) is from animal models and gnotobiotic mice. The problem with previous studies (and I mean previous for those studies done before any of this was known) is that they focus on specific macronutrients or foods (animal vs. plant foods) rather than specific nutrients (fatty acid profile, etc.). It would be ludicrous to think that diet alone can cure all autoimmune diseases, but IMO, it is important for long-term success. (cont...) – Lucas Tafur Mar 28 2012 at 2:57
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Most studies done, for instance, on fecal transplantation for C.difficile infection have follow ups (if Im not mistaken) for 2 years maximum. And that is focussing only in the recurrence of infection. Here is a must read for anyone interested in nutrition and the gut microbiome: lecomprime.com/wp-content/uploads/2011/09/… Regarding T-cell differentiation, distinct metabolic profiles have been characterized recently: ncbi.nlm.nih.gov/pubmed/21317389. However, we must aknowledge that it is only part of the picture (cont..) – Lucas Tafur Mar 28 2012 at 3:00
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Great topic!

I think Dr. Harris has nailed it again.

An old friend once used the phrase, "Her pathology has become her theology." I think this sums up what Dr. Harris is saying.

Going Primal has given me the opportunity to experience real health for the first time in my life--so the avoidance of certain foods (esp. gluten & FODMAPS) has been very beneficial to me.

From my new perspective, I am pursuing further healing of my gut so that I can eat more freely when socializing. Needing to avoid guacamole (while living in New Mexico) because of the FODMAPS in avocados and onions has been great incentive to do this! And thanks to Melissa & others who have posted here, I feel more confident of my body's ability to heal fully, given the time and space it needs.

In my work in the birth world, I have learned how much our U.S. medicalised pregnancy & birth practices are setting up a large percentage of the population to have impacted gut health.

Babies have a sterile gut, so it is essential that it is populated by beneficial gut bacteria if they are to enjoy good health. With over 30% of births being caesarians, many babies aren't getting exposed to the flora of their mom right away because they are missing the journey through the vagina.

Prophylactic antibiotics are killing off beneficial gut flora in many moms before they even have a chance to inoculate their baby. Even if they have a vaginal birth, many moms are suffering from gut flora imbalance that they pass on to their babies.

And the poor rates of exclusive breastfeeding until 6 months (WHO recommendations) means that many, many babies are being exposed to gluten, soy & other foods that their bodies are not yet ready to digest, further disturbing their gut environment.

I am a fine example of this. When I was born (vaginally) in the hospital in 1963, my mom was given antibiotics at the end of her pregnancy because she was fighting an infection. Also, I was not breastfed--in fact, she couldn't afford formula, so as soon as we were home, I was fed condensed milk (probably sweetened!)

There is a growing awareness of this issue among birth professionals, but really, it is up to the parents to defend the gut health of their children, if they want to truly support our population's future health.

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From one midwife to another, I really enjoyed your commentary regarding medicalization of birth and health/food/life outcomes. I'd like to add that it isn't just birth, but THROUGHOUT life, that it is important to be aware of how medical intervention can have untoward consequences... that antibiotic for an ear infection may shorten the duration of THIS illness... but I believe that it also destroys our immune system's ability to defend itself, until we become virtually addicted to outside defenses to face our world... and must put up with the damage they do in the process. – Firestorm Mar 25 2012 at 17:16
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I have the same story when I was born in 1973. I was born via caesarian, and while I was breastfed a bit, my mom ceased to have milk soon after, and after that my parents had only money for cheap milk, which was full of weird hormones in it. I was one of these kids that failed to thrive. I got all my height (4'11") until the age of 10, and then I just stopped there. I never grew an inch after that (according to doctors, I should have been 3 inches taller). All my ailments started then from falling hair, to ADD, and when I moved to the US 11 years ago, the super-gluten here got me some IBS too – Eugenia Mar 25 2012 at 18:47
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Firestorm~ I absolutely agree. The funny thing is, that many so-called illnesses of childhood (like ear infections) are often not seen with children who have a mom with good Vitamin D and nutritional status throughout pregnancy(plus very healthy gut flora), an unmedicated vaginal home birth and exclusive breastfeeding for 6+ months. – Dragonfly Mar 25 2012 at 19:09
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'defend the gut health of our children'. EXCELLENT comments Dragonfly!! My parents thought they were doing us a favor (being physicians) giving us antibiotics for many of our fevers and sniffles but each on of my 4 siblings have had an autoimmune disease. I got formula from day one. You trace the history of the many factors of our current disease epidemic well you guys on thus thread....!!!! U girls rock! – grace Mar 25 2012 at 22:13
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Thanks for sharing DragonFly! I really enjoyed reading this post and agree 100%. – Eric Mar 26 2012 at 4:02
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Yes, paleo is a band-aid. No, paleo is not a cure-all. No, calling paleo a band-aid does not in any way detract from it, or from those who have successfully used it to achieve their health goals.

But for every person who has achieved vibrant health and six pack abs through eating a nutrient dense paleo diet, there are others who have failed. Go take a look at a handful of paleohacks questions for evidence of this. Most of the advice for these people who are "failing" is to "Go more paleo!" or some other version of this. It's eerily reminiscent of the vegan crowd, where people who aren't thriving must not be doing it right, or need to go even more vegan. "Try a 30 day juice fast raw protocol, yo!"

The paleo community is better than that, and even if you're already on board with Dr. Harris's skepticism about over-reaching health claims, I still think it's always good to hear another wake-up call. My first was with Mat Lalonde's AHS seminar, which basically told me to study actual science or STFU. This was another wake-up call I definitely needed, because part of me still believed that if everyone went paleo from birth, the diseases of civilization would go away. Today, I'm realizing that is most likely not true.

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Hugh gets what I am saying. Check out the big brain on Hugh : ) – Kurt G Harris MD Mar 29 2012 at 3:54
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^^ :D +1 for the reference. – conciliator Mar 31 2012 at 5:50
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My question is... Did anyone actually ever think Paleo cured anything? To me it seemed clear that the diet was a long term lifestyle treatment. I hardly see anyone doing Paleo/PHD/Peat/Primal etc for the 3 months, calling themselves cured only to happily return to the SAD. What makes paleo better than a drug treatment is all around more beneficial than whatever that specific drug is targeting.

Seriously, if there was a cure for these ailments, don't you think people would be eating whatever the hell they wanted? I love eating whole foods, but if someone told me I could eat pizza and cookies everyday and not get acne, fat, etc etc then by all means I'd be having them for breakfast.

Whatever the reason you go "Paleo" or diet that fits under the "WAP, WHOLE FOODS" umbrella, they are all focused on whole foods and cutting out the junk. Of course that's a treatment and not a cure... because you have to be regular and consistent about it.

I don't think what Kurt is saying is sensational or a revelation at all. How was this not obvious from the start?

It is true though that the people going ultra restrictive are not doing themselves any good... Perhaps the remark is good for that. But who cares if he eats wheat ad lib?

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I did. Or hoped... – Satchmo Mar 29 2012 at 3:28
Thank you very very much Bill. I thought I was the only one thinking of it like this. I never thought about paleo as curative either, and just didn't understand what was so special about Dr. Harris' statements... He's just putting into words what we're all thinking ('*will I never be able to eat pizza again?*'). Nothing new. – Bruno Mar 29 2012 at 15:25
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Kurt Harris has, with his brief comment, delivered what may prove to be very deep insight into the nature of health & diet. (It may also disturb some of you too. C'est la vie.)

His observation that Paleo might be palliative rather than curative is non-trivial, and deserves further exploration and meaningful discussion.

Things just got very interesting again, and cheers to that!

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My cheers added. If all I'd done was "switch to paleo" I wouldn't be able to eat half of the foods I'm currently enjoying. I'm sure I/we have much more to learn and it's more than time to open our minds. – Nance Mar 28 2012 at 1:37
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We're smarter together than we are alone. Without this constant influx of debate and new ideas, we would be much farther from the general curative solution. I am greatly interested in seeing what insights putting all of our chips in the pot will produce in the shorter and longer terms. – air_hadoken Mar 28 2012 at 3:25
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This is like saying Robb Wolf had an intolerance for cyanide, and paleo didn't cure that intolerance, only abstinence to cyanide prevented him from a quick death. So, therefore a cyanide free diet is not curative, it's only a band-aid. (Who knows, maybe there exists a human that can tolerate cyanide, or will in the future, maybe with the same adaptation that golden bamboo lemurs have). Genetics is a funny thing.

But Seriously? It's come to this sort of nit picking semantics?

Yes, of course, there is a difference between saying someone is allergic, or intolerant to a particular food, but let's not argue about semantics so closely when in both cases they are suffering from damage caused by that food. Removing that food might not reverse the damage immediately, and maybe never fully reverse it, but continuing to ingest it is more likely to continue causing more damage and prevent the healing process.

On the other hand, people who have no reaction to wheat toxins, will happily go on eating toxins that inflame their guts and cause all sorts of problems, such as autoimmune issues, poor nutrient absorption, etc. and they'll have no idea that it's actually happening until very late in the process.

Paleo is never going to fix you so you can eat neolithic agents of disease without them causing damage. To call it a bandaid is just trying to be sensationalist, in the same way I used cyanide in the counter.

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You didn't read all the comments did you? – Satchmo Mar 29 2012 at 3:27
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"...there are many many people who eat PERFECTLY in every way that still have serious DOCs is telling us something.

It is telling us to look at other things."

Perhaps HORMONES that have an interaction with the thymus has something to do with it.

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Danny you are cool guy but are being misled by nonsense. Stop reading Ray Peat and start reading Graham Rook – Kurt G Harris MD Mar 28 2012 at 16:39
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@Dr. Harris, I'll just add your response to the pile then. He writes, in depth, about that vague statement with his research on the anti-respiratory factors like endotoxin, adrenaline, cortisol, serotonin, estrogen, prolactin, PTH, and the thyroid inhibiting properties of free fatty acids (which Masterjohn supports—he must be insane too). There's no doubt in my mind that within a few years paleo and Peat will be mostly aligned. The ebb and flow of the paleosphere is almost comical. I will take criticisms of Peat's ideas more seriously when the due diligence to debunk his work is more apparent. – dannyroddy Mar 28 2012 at 19:37
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Danny, Ray has a single paper in Pubmed from 40 years ago, plus a letter to the editor (ncbi.nlm.nih.gov/pmc/articles/PMC2571272/pdf/…). Your link gives Ray credit for 3 papers by Rachel A Peat.... In any case, the literature he should be judged on is that on his site, not his work on Pubmed. – Paul Jaminet Mar 28 2012 at 22:59
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And I'm not overly swayed by an avocado article on "Avocado oils and hepatic lipid metabolism in growing rats". If I extrapolated studies on growing rats to humans, I would not be able to eat very many things at all. – Kamal Mar 29 2012 at 14:30
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Personally, I am a diet agnostic. I like to read broadly and take about 10% of what I learn from various writers with me. What I am curious about is what draws Danny, Cliff, Steven and the other Peaters to this PALEO exchange site? I really don't mind, I read Peat too. I am just genuinely curious what y'all get out of it? Exercise in constructing arguments? Attempting to convert lost souls? Marketing? Again, not an attack here at all. I would LOVE to know this answer. – none Mar 29 2012 at 15:40
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Considering that I'm never going to have a time machine that lets me go back and do it all over the right way, the whole palliative vs. curative shtick is, IMO, a ridiculous exercise in intellectual masturbation. Fine... I have a never cured, permanently damaged, crippled physiology that needs the palliative crutch of avoiding certain foods. I can happily live with that. The diet works, regardless of any palliative vs. cure beliefs I could have about it.

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Love this answer, Alex. Or I don't get Dr. Harris' point, or he's just saying something we all know : we'll have to keep avoiding gluten as long as we don't find the underlying cause. So what? Is it that hard to avoid pizza? – Bruno Mar 28 2012 at 13:59
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Did anyone actually read the whole thread at Melissa" blog? I guess not. If you had diabetes it would not interest you to find out you could eat like a normal person if you fixed it? You actually think eating pizza CAUSES disease because pizza itself is evil? Amazing! – Kurt G Harris MD Mar 28 2012 at 16:14
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I don't understand why you're so fixated on belief, which is merely mind addicted to ideas. IMO, "OMG! You believe paleo is curative rather than palliative!" is as ridiculous a concern as "OMG! You believe in Buddha instead of Jesus!" Now, if belief drives one to act out stupidly, that's a different story. If I decided to live with a thermometer up my ass while binging on crap, believing it would cure my thyroid, by all means, be concerned. But, if a person has an enhanced quality of life by avoiding certain foods, what difference does it make if he believes it is curative or palliative? – Alex Mar 28 2012 at 16:51
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A decision to stop learning based on belief that one already has all the answers would come under acting out stupidly. IMO, one should never stop learning. As for the hygiene hypothesis, I have been aware of it and the concept of helminthic therapy for a number of years, but I have not been diagnosed with an autoimmune disease, so as far as I know, there's currently nothing there for me to pursue. And, I'm sure as hell not going blindly join the raw paleo fringe in believing raw meat cultured with human feces is some kind of curative "food" that I should be eating. – Alex Mar 28 2012 at 19:26
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In my particular case, I have no belief that my diet diet is curative, but if I did believe it was curative, no harm would come from that belief unless bodily feedback started telling me more than just diet was needed, and I ignored the signals based on that belief. – Alex Mar 28 2012 at 19:36
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I'm just going to go back to eating donuts.

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Alcholics who quit alcohol are just band aiding their alcoholism (eliminating alcohol is the solution). Drug addicts should go back to using drugs once they are healed and sober, because it would just be a band aid if they didn't reintroduce the problematic substance. If you get a flat tire, don't bother looking for the nail in your driveway, just go get a new tire... we have to ELIMINATE problems, and calling it a band aid is just ridiculous and conceited thinking. Problematic foods are PROBLEMATIC. No argument, debate or counter needed.

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We are meant to eat food. It's not the same as drugs or alcohol. If you can restore gut function/gut flora, eating the widest possible mix of whole foods makes sense. If a sweet potato causes problems for me, then I can't eat it for now. If I can eat it next month because of improved gut function, then why not? – Nance Mar 26 2012 at 2:44
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There is a nuance, George. Alcohol is not necessarily natural and good, it's made by humans. Drugs too. Problematic foods are often completely natural, so it doesn't make sense people don't tolerate them. I mean, if someone doesn't tolerate beef, don't you think there's something wrong with their body, and not with beef? – Bruno Mar 26 2012 at 6:44
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Nance/Bruno.....we may not be meant to drink or do drugs and it may not be natural or good (debatable), but neither is gluten or wheat. That's the point George is trying to make. – hemanvt Mar 26 2012 at 13:44
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We;re not meant to eat GMO food. Which is... MAN MADE FOOD. – George Brodie Mar 27 2012 at 6:38
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Also, there are plenty of drugs that are not manmade. – George Brodie Mar 27 2012 at 6:40
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OK, in the interest of giving Ray Peat a fair shake, I just spent 10 minutes on his website. I searched for the term "thymus" and immediately got this article, which argues THAT HIV IS NOT THE CAUSE OF AIDS. As Dave Barry would say "I am not making this up".

http://raypeat.com/articles/articles/immunodeficiency.shtml

Read it for yourself. I'll wait patiently for all the Peat Defenders to regain their senses and apologize for attacking me here. Or admit they have no critical reasoning powers. Either will do.

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So, Kurt, let very carefully qualify my forthcoming comment: 1) I am NOT a Peatarian (although I am very intrigued by his ideas) 2) and you well know I respect your intellect. 3) And I subscribe to the view that HIV DOES cause AIDS BUT......other smart & esteemed folks share his view too. Namely Duesberg of Berkeley. For fun reading, see here post & comments here: blog.sethroberts.net/2010/04/11/… – Patrik Mar 29 2012 at 5:16
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Why did you tell Danny Roddy to stop reading Ray Peat if you didn't try reading him yourself yet??? And now you're judging others in 10 minutes? – Bruno Mar 29 2012 at 6:24
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I apologize and have come to my senses. I also have no critical reasoning skills. One thing about Peat - I am no longer afraid of orange juice. Where can I get some of these worms? My 7-11 has live bait... – Dave S. Mar 29 2012 at 14:11
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There are Berkeley Professors who believe in intelligent design I'm sure as well. And regarding Roddy, he said he tested many lab variables and found anomolies in everyone. That's pure statistics, assuming normal distributions you have 5% of variables outside of 2 SDs, so if you test 20 variables you are expected to have something awry. And finally, adrenaline and noradrenaline are fight or flight hormones, yes, but it's not that simple. Having too much is bad but having too little is bad too. Can someone explain why healthy regular endurance exercise raises catecholamine secretion at rest? – conciliator Mar 30 2012 at 20:47
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"i will use the one time i think you are wrong everytime you say anything to prove that you are wrong because ..." this is jilted lover syndrome at its finest. no one is saying that everyone is 100% right all of the time, but even if peat is wrong about the cause of AIDS, does that mean that he is wrong about the thyroid, or that danny roddy hasn't helped some people by giving them advice he gained by implementing peat eating strategies? – dsohei Mar 31 2012 at 23:35
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I don't know if he understands what GAPS is, because if he did, he would see that they are on the same side. GAPS is very restrictive at first to give the gut a chance to heal, but then it is pretty aggressive about introducing foods back into the diet as soon as you can tolerate them. It's not meant to be restrictive long-term.

I do agree that most "allergies" really do start in the gut. That's my experience definitely. However, his response here seems to imply that eliminating foods doesn't help to cure anything. I disagree, at least as much as eliminating things you react to gives your body time to heal. I know that going out and eating all the things I am sensitive to on principle would just drive my immune system bonkers.

I would like to know what he believes is the right way to go about healing your immune system. I am assuming he discusses that somewhere else, since it's not there.

(oh and on a personal note, he used way too many acronyms)

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I am waiting for him to post something up on his blog so we could get better insight into his views. – ROB Mar 25 2012 at 21:45
rob, have you read his comment thread on melissa's post? pretty much sums up his current views. – dsohei Mar 27 2012 at 21:22
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I've mentioned many times over the past year on Paleohacks(and completely ignored:) that there is way more to gut health than metabolic interventions. Gut issues involve physical issues, "scars" in the intestines.Find a good neuromuscular therapist who knows how to treat the organs of digestion and anyone, ANYONE will multiple the effects of any and all dietary interventions by a factor of two to ten !!!! It's like playing basketball with one arm vs. two. We can't go back into the womb and come out "properly", we can't go back and change out our crappy formula for breast milk of a Paleo mother, but we can try healing our gut with "two arms". A good neuormuscular therapist can provide in one hour,(actually 0ne half hour!) the equivalent of gallons of fermented food, pots of bone broth, bottles of probiotic pill. The stomach, small and large intestine need to be touched. and touched regularly. ... Kurt Harris is my favoritve Paleo maven, and he probably is correct in almost everything he says/writes, but he is basing the above view on observing one armed basketball players. There are other "health/healing" geniuses out there. Paul ST John is one of them. Let's play ball with two arms for a while and then revisit this question.

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Do u have some links? – dsohei Mar 27 2012 at 8:57
This is an interesting concept. It joins a couple of ideas I have seen in Tai Chi Chuan books; that the slow movements of TC gently massage the internal organs, and some TCC masters have cured their own very serious illnesses by taking up TCC. I second the request for links about neuromuscular interventions. – Kirk Mar 28 2012 at 17:21
You certainly like to tease. – primallykosher Mar 30 2012 at 12:05
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Is this idea being that our genetic make-up and developed immune system is responsible for our health more so than what we eat once we are adults? It does seem relevant, even obvious - with implications to help us fight disease in the future. However, where does that leave so-called primitive tribes/cultures who had good health that then failed once introduced to the SAD - ? The fact their health failed dramatically would seem to indicate the inflammatory, disease promoting aspects of said foods introduced.

Why then, would this happen? I am still not acquainted with a primitive group of peoples who used gluten grains as their staple, much less canola oil and sugar! Dr. Harris, if I'm not mistaken you coined the 'neolithic agents of disease'term - as much as I see the new direction and how pithy it is, I do believe there is indeed something in reality that is NAD and the avoidance of such, even in healthy peoples, is to be desired.

I do understand that you are not saying diet has no effect on health. I do understand you are saying that the issue is immune related, genetic, the early environment. And once damaged therein lies the root issue. But, as I remarked - this does not apply to primitives introduced to SAD who decline in health markedly. It would seem that diet might be more important after all - ?

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I don't have credentials and those who do can answer from that perspective. As I've mentioned, I happened to grow up in a way that gave me a fairly traditional and robust immune system. I am incredibly sensitive to additives and fake foods, perhaps more so than average. And, as is seen with the traditional folks you mentioned I responded very quickly and well to a whole-foods diet. Since my body knows exactly what it wants, I figure that's why it got so angry in response to junk food? – Nance Mar 29 2012 at 2:55
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@Cindy. Thanks for recognizing that I coined the term NAD.But a neolithic agent of disease can be anything - a habit, something present we are not adapted to, or something missing that we need. I am all about finding out what they are. The list may grow or shrink. – Kurt G Harris MD Mar 29 2012 at 4:00
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To answer your question: for some people, in certain cases, food avoidance is the best available choice currently. But it is not addressing the cause, mainly because the cause is probably beyond our current comprehension.

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Let's not lose sight of an important distinction, when we talk about what Paleo can be good for.

If we're only focused on the autoimmune issues prevalent in many of us and our society, that is if we are talking about obesity, thryoiditis, ASD, diabetes, celiac, corn intolerance, psoriasis and skin issues, etc., then I would agree with KGH. Paleo itself is not going to heal me and prevent bad proteins from getting in, or my immune system from attacking my own tissues. KGH's post and his response in this thread seems to be tailored to this particular issue.

But I'm worried when I see a comment like "I still think diet matters, but I no longer see the most important NADs as likely to be particular foods to avoid." Are not the foods we consider to be NADs the richest sources of LA, fructose, and phytates? We focus on foods to avoid instead of molecules to avoid, not because we are uninterested on a chemical level why they're the NADs, but because foods do not announce to us, "Hey! Linoleic acid here! Got a bunch!"

The other half of the distinction lies in longer-term diseases: not the autoimmune ones we're dealing with in this context, but things like GERD, tooth decay, heart disease, cancer, arthritis, and dementia? Few of these things affect me acutely, but if I don't care and eat SAD now, some or all will affect me eventually. I'm not just doing paleo to fix what's wrong with me now. I'm doing paleo because I care about making it to 75 with the ability to enjoy life and good years ahead of me. Avoiding the diseases of civilization, not the ones that exploded in the last 50 years but the ones we've had to endure for 5000 years, that's what I currently believe paleo can do for me. That's a cure.

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GERD, periodontal disease, heart disease many forms of arthritis and possibly dementia and cancer have elements of immune dysregulation involved. Read the symposium edited by Graham Rook before deciding these are not immune diseases. There is plenty of evidence most of them are. And I have not once said diet is not important, only that it may be less important than other things. I do nt drink big gulps and eat hot pockets. I still mainly eat pastured meats, fish, starchy veggies and green salads.etc. – Kurt G Harris MD Mar 28 2012 at 16:19
Kurt, I think much of this thread is evidence that what we argue most heatedly about is not the words you are saying or not saying, but the concepts people are taking away from reading and (mis)interpreting those words you do say. I'll check out the Rook sources when I have reading time. – air_hadoken Mar 28 2012 at 21:03
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It is obvious watching PaleoHacks that there are bunch of sick people out there. It's also apparent that these sick people are sick not because of the food they haven't yet eliminated from their diet but some other factor. When you're sick or reactive to everything this suggests you’re far from normal.

This shouldn't be a mystery to anyone engaging in critical thinking. A limited and strict “paleo” diet does not fit in with our evolutionary model (whatever that is supposed to mean) as it is much too limited for us to have dispersed across the globe as quickly as we did. Just take a brief moment of pause and reflect on the numerous and varied diets across the globe. We all have pretty similar life expectancy and we all eat a lot of different crap. If you had to migrate to a new land and you reacted to the food available, tough shit, your dead.

When it comes to things like deciding what not to eat we just have to use our brains. Almond flour? Coconut flour? (Insert your favorite nut here) flour? And other modern inventions that would otherwise be sub-optimal because they are a pain in the ass and otherwise don't offer any benefit. Get real. It seems that most of the damage done is done by our tendency to trust cultural fads over our common sense (who became a vegetarian without a little self-convincing?) and by environment and over sterilization.

It seems problems are caused more from what we aren't eating rather than what we are eating. What normal person eats liver anymore? Or the rest of the animal? Yet it was once pretty common. Our sickly society largely has its roots in culture i.e. when we began trusting experts and government panels over what tasted good (naturally tasted good not engineered cheese flavored horse shit). Notice we are now to the point where a fucking radiologist is dishing out health advice--"I used to think so too. But now I don't."--heard that bullshit from the same guy before.

If we want to be real we have to understand one thing, that is, as our diet has become shittier our life expectancy has gone up. Interesting. On the surface this seems like garbage logic but if we consider the idea that anytime food energy becomes available sustainably there seems to be an explosion of civilization and culture. That tendency has more to do with available energy rather than what exactly it is we are eating. Who looks at civilization as a bad thing? I would view proliferation of the species as a good thing.

It's easy to cite collateral damage like more disease and disorders etc., but I'd argue this is rather similar to what happens to commercial animals who live ass-to-ass and are fed some type of barfed up corn mixture. They get sick. They get all kinds of disease. And then they load them with antibiotics. Do you think in those same types of living conditions that if instead they replaced the corn with grass that it would really make a significant difference? Apparently not, because most of you replaced SAD with FOOD and you still are sick. You see this same thing with zoo animals, pets, etc. They all get shitty when taken out of their normal element and start suffering with different "unknown" diseases. Hmm. Immune system. Not a new idea. Undervalued? Yes. But not a new idea.

Human eating traditions don't get passed down over millennia by random chance, it's passed down because it works (so anything normal you can't eat should cause you pause), perhaps if we explored some of our passed down "common sense" with science instead of looking to science to invent or reinvent common sense we'd learn something practical and expandable and probably would progress a bit faster.

Essentially in the mainstream we've rejected the possibly that tradition has its roots in sound reasoning, rejecting our ancestors as primal idiots, eating these random weird diets, etc. We can't even fathom the possibility that in some way tradition might be a form of "science" itself, tested (we are still here) and sound, because there aren't any fucking bar graphs and pie charts to go along with it.

Anyway stop taking folks so seriously things like "I'm starting to think" or "I believe" should make any rational person pause and investigate for themselves rather than fall into the same "expert" cycle.

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We can't even fathom the possibility that in some way tradition might be a form of "science" itself, tested (we are still here) and sound, because there aren't any fucking bar graphs and pie charts to go along with it. love that part, Edward. Effin great answer. – Korion Mar 30 2012 at 10:48
we ARE the commercial animals,not merely"rather similar" to the commercial animals. Great answer, as usual. – shah78 Mar 30 2012 at 11:49
"as our diet has become shittier our life expectancy has gone up." Longevity has more to do with vaccinations, prenatal care, reduced infant morality rates and trauma care. All it means is we're very good at keeping you alive, depsite suffering from multiple autoimmune and degenrative diseases of civilization. Once again, this is like reading Peat: no cogent argument, no cohrent thought or any pattern of reasoning from A to B. It's basically a rant, parts of which seem plausible given what has transpired but most of it is just random mush and doodling. – Namby Pamby Mar 30 2012 at 15:45
Prenatal "care" and the rest of the factors you listed (except trauma care in some cases), has nothing to do with increasing longevity. You're listing factors for mortality and quality of life I'm talking about longevity. There is a difference. I'm not talking about evolutionary masterpieces such as yourself who would otherwise fail to thrive under primitive circumstances pushing up statistical averages. The only thing incoherent is your superb reasoning ability and reading comprehension. – Edward J. Edmonds Mar 30 2012 at 17:55
Interesting observation on tradition as science, but it makes me wonder what you think qualifies something as "traditional." – Tom Pentzer Mar 31 2012 at 22:47
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Paleo may be a band aid, but it is a band aid that prevents further infection/diseases via inflammation.

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Explain exactly how "paleo" prevents inflammation. I mean, let's say you meet someone eating a perfect paleo diet and it has no effect on their multiple sclerosis, or chronic sinusitis or rheumatoid arthritis. Explain why the prevention provided by paleo diets is so powerful yet so ineffective if you have REAL inflammation. – Kurt G Harris MD Mar 28 2012 at 16:22
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Granted that huge amounts of excess LA and excess calories and body fat elevate inflammatory cytokines. Stipulated. Do you really think excess LA and being a bit fat is the main cause of autoimmune diseases? – Kurt G Harris MD Mar 28 2012 at 16:24
@ Dr Harris: I think the key in Anthony's statement was "prevents FURTHER infections/diseases via inflammation", in that the elimination of inflammation inducing foods lowers unnecessary and easily "curable" inflammation through avoidance. – Tyler Mar 28 2012 at 19:52
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Dr. H, do you not believe in Fassano's gut permeability with regard to the genesis of autoimmunity? That's all the rage because it posits a common pathogenesis of all autoimmune diseases. Granted, it probably requires genetic vulnerability + possibly gluten + inflammation + weakened immune system + environmental agents. But however attained, making your gut impermeable is supposed to be the key to not AGGRAVATING autoimmunity; let's leave alone CURING or even pushing it into REMISSION. If so, all Paleo means is just doing what's under your control: do your part by keeping your diet clean. – Namby Pamby Mar 28 2012 at 21:10
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@ Dr. Harris a band aid is a band aid, and until we learn more about symbiotic gut flora and fauna, i am going to keep the band aid on my gut. – Anthony Pierre Mar 28 2012 at 22:02
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Dr. H is right about one thang. Paleo is incomplete in one aspect. It's not just the food. It's the environmental toxins, germs, immunization shots, cleaning agents, cooking utensils, bacteria, and anti-bacteria brought about by our antiseptic, modern lifestyle. Also factor in the inflammation caused by our electronic and communications gadgetry, including our beloved microwave.

Drs. Sinatra and Hyman do talk about these. Admittedly, it's a broad and subjective realm that's hard to tackle. But it should be addressed given how little we know about their impact. I do agree that food alone isn't gonna fix autoimmunity. And it wasn't just food that brought about my autoimmunity. I'm not talking about genetics. I'm talking about that big X Factor, the environment.

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I'm not educated enough about the topics you point out here, but I, too, am circling around the fact that everything about our modern lives is just wrong and stacked against us. Our human drive for comfort and stability will be the end of us. – Karen P. Mar 28 2012 at 22:00
When I went overseas for 2 weeks, I was afraid I was gonna have a flare up as I wouldn't be able to avoid eating out. Well, my Sjogren symptoms were in complete remission while I was there, when I was eating nightshades, dairy, even gluten. Then, a week after I came home and started back my very strict autoimmune diet (gluten/dairy/nightshade/soy/nut-free), I had one of my worst flare ups. Then it occurred to me. Autoimmunity is cyclical and comes in waves -- may not correlate with diet. This is one of those "spurious associations" Dr. H is talking about. I do agree w/that. – Namby Pamby Mar 29 2012 at 3:25
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"It's the environmental toxins, germs, immunization shots, cleaning agents, cooking utensils, bacteria, and anti-bacteria brought about by our antiseptic, modern lifestyle. Also factor in the inflammation caused by our electronic and communications gadgetry, including our beloved microwave." You I'm now convinced are a moron you've have not read Peat's work. If anything should echo in your brain about Peat is his phobia of the external environment. He's mentioned all of these as factors and their roles. Peat has talked about these factors for years (...) – Edward J. Edmonds Mar 30 2012 at 19:56
and further these concepts are mentioned on his about page and the first few paragraphs of his home page. What you talkin bout Willis? – Edward J. Edmonds Mar 30 2012 at 20:00
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Nice try. Again you fail to convince the reader of any significant reading comprehension reducing everything down to doodles and rants and dick sucking. You imply you read Peat by speaking in an inflammatory way about Peat in other responses further you say "Dr. H is right about one thang. Paleo is incomplete in one aspect. It's not just the food. It's the environmental..." you mind as well change your name to Percy you've made your position clear. – Edward J. Edmonds Mar 31 2012 at 1:31
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I think all the detractors in this thread combined have probably read < 10% of the literature on the subject as Dr Harris. You can't just follow all the blogs guys and think you know that the hell is going on, it doesn't work like that.

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Also in this thread: bruno just being an annoying voice without actually adding anything of substance (whilst complaining about lack of substance) ! – Cave Man Mind Mar 29 2012 at 14:04
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Bruno, meet Kamal, an amateur actually adding to the discussion! – Cave Man Mind Mar 29 2012 at 14:05
WRT diet and health, I actually agree with everything Kurt is saying. I just don't get his bizarre fixation on belief. – Alex Mar 29 2012 at 14:10
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Cave Man Mind, what are you adding then? Hypocrite... It isn't my job to add anything of substance, but I felt the need to criticize Dr. Harris because he's way too popular (which is why I agree with your answer : he's so popular people applaud him without actually reading his stuff). If that means I'm the dick, so be it. – Bruno Mar 29 2012 at 15:15
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You are definitely being a dick by starting this thread because I am "way too popular". Maybe you should produce a documentary about me to protest my popularity. Or print T-shirts with my image on it as a form of protest. That would make as much sense as what you are doing here. – Kurt G Harris MD Mar 29 2012 at 20:49
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Besides palliative and curative, what about preventative? I'm not sure how many paleos actually thought the lifestyle truly cured existing problems, but I'm pretty sure a lot of people believed it prevented the creation of the problem in the first place for those who didn't have it yet, e.g. the idea that gluten -> leaky gut -> new autoimmune problems for some people.

Now it was mentioned gluten is not a NAD, though I'm not sure how things are classified as a NAD or not. Is it because some people can eat it just fine? Then if some people can eat excessive amounts of fructose or LA (whether now or in the future), does that mean those things are not NADs either? What about lactose for lactose intolerant people? Where do we draw the line, which seems to be what the argument(s) is really about. This is especially confusing since the archevore site itself also says to avoid gluten (though I'm guessing maybe his position's changed since then). I'm suspecting maybe NADs are something that needs to be defined on a per-individual basis. So it is technically incorrect to say, this this and that are NADS, and this this and that are not NADS without qualifying with "for X individual"

Maybe redundant with the what is a NAD question above, but if paleo neither cures nor prevents anything, then it would seem there is no good (health) reason to promote it to anyone not already suffering from problems, no more than it's a good idea to prescribe any other form of treatment to those who are healthy.

Additionally, IS there something remotely resembling a cure? And/or what should we do then in the meantime for optimal health?

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you can improve on paleo, but you can also just trade problems on paleo. same can be said for any diet because everybody is uniquely individual. hopefully u cover your nutrient bases, reduce diet related stress and stay out of the red zone. for some that is easier than for others... – dsohei Mar 31 2012 at 23:39
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Can just someone tell me what to eat and when and what not to ?

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Sure. Pay close attention to what you eat and how you react. Eat whole foods andcuts ofwhole meat. Eat only when the urge comes from your stomach/gut vs. your brain (cravings.) Avoid manufactured food-like products. – Nance Mar 29 2012 at 17:13
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Read this: gnolls.org/1141/… – Nance Mar 29 2012 at 20:02
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Also read this: archevore.com/get-started – Nance Mar 29 2012 at 20:02
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and after you've done this for a few years, if you haven't gotten the results you want, it'll either be your fault or tough luck :) but you have to give it a long shot first – dsohei Mar 31 2012 at 23:41
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I dont agree with Dr H.

Edit: My point with the athlete analogy is, that athletes go through stress. They reduce that stress by consuming adequate carbs. Peat's suggestion that people should eat adequate carbs is not some kind of cherry-picked idiotic claim. Everybody has a different level of carbohydrate need. Some people need more carbs than others. Peat recognizes this. If you don't get enough carbs, the liver can't have adequate T4 to T3 turnover because there is insufficient glycogen. FFA's begin to be used as primary energy which also shuts down the thyroid gland. Free radical by products result from FFA oxidation and you begin to have a need for antioxidants. Vitamin E becomes deficient, and the need for vitamin e greatly increases. Fatty acid oxidation and release induces prostaglandin modulation of the aromatase enzyme which will convert testosterone to estrogen, furthering the metabolism's shift for burning fat for fuel instead of glucose. Ever smell a females breath when estrogen is spiked? Yep Acetone! Then, it gets worse, cortisol is released to induce gluconeogenesis from the liver to break down amino acids released from lean tissue. Your body begins to eat itself, and your myo-catabolic environment encourages the repartitioning end result of less lean muscle and more fat mass. The ratio becomes worse. Since you are mainly running on catacholamines on a low carb diet, you are continuously cold in the periphery. You get very shitty sleep because you can't quiet down at night as a result of this. Been there done that for 3 years. Low Carb Dieting was a waste of time for me, and only made me worse. Paleo dieting is not inherently bad, but I bet any of you can't even describe what paleo is or what it should be? What did our ancestors eat 10000 years ago? Did you personally go back in time and observe them? Is it better to use the observations of Weston Price and other explorers, and current observation for what indigenous populations REALLY eat? Probably!

But I gotta say that one thing Dr. H claims is that there are other aspects to health besides diet. I agree wholeheartedly, but do realize that whether or not these environmental aspects play a huge role, there still is a vast degree of physiological processes that are able to resist these issues. He mentions Doctors visiting islands with natives who had parasites, and curing them. We are not natives!!! He mentions that a large majority of people had a food allergy that was a result of a frequency problem. Since when has there been any culture pre 17th century who didn't consume just about the same foods every day? If you were a swizerland dairy farmer, guess what you were eating the next day? Milk, eggs, and possibly some grains. This is obviously not scientific evidence rather than observational and epidemiological research but by god Dr. H, if you are going to argue the old food frequency thing, you better be arguing with the entire globe before three hundred years ago. Could he be right with this? sure, but it says nothing about his disagreement with Peat, other than maybe he doesn't feel like its healthy to eat the same foods every day, which is based on "iffy" science and opinion rather than fact.

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LMAO dude... I dig Peat's writings and Danny Roddy works really hard to make them accessible to people... but your answer is seriously LOL worthy. You make threats that the disbelievers will run crying to Peat... Seriously bro? SERIOUSLY? The quote from Harris that this discussion pertains to has honestly nothing to do with Peat. Further, your attack Dr. Harris's character with an answer that quite frankly, reflects incredibly poorly on yours. – Bill Mar 29 2012 at 2:23
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Nah, you my friends are the joke of this site. Dr. H was getting back from me what he was giving, which was ludicrous disrespect towards somebody without reason. Whether right or wrong, Dr. H has no grounds telling people that Ray Peat is full of shit. Why??? Surely a doctor should have some kind of rebuttal rather than a childish "full of shit response." You guys are so blind that you don't see that I am on your side. Here we have a doctor spewing out radical claims and shouting down others simply based on opinion, which I think is dangerous, and can wrongfully change peoples' opinions. – Steven Smith Mar 29 2012 at 2:34
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A reasoned argument disputing what you felt were errors in Dr Harris's statements would have found some listeners. I don't think Danny or others who have areas of agreement with Dr Peat would applaud the words you chose. – Nance Mar 29 2012 at 2:44
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@ Steven. I shouted no one down, I just offered advice to Danny Roddy, whom I have know for years. I was not addressing you and this thread is not about Ray Peat nor was my original post on HGL. That said, I do not know a single MD who takes Ray Peat seriously. Not one. It is not a matter of dissing him or disagreeing with him, it is that we do usually don't read him more than once. Being attached to someone like Peat to the point of rage when someone dismisses him is not a sign of a very critical mind, maybe. – Kurt G Harris MD Mar 29 2012 at 4:26
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And who said anything about food frequency? Not me. I only specifically addressed a claim about the thymus which is demonstrably factually wrong and which was claimed to have originated with Peat. None of the rest of your rant has anything at all to do with anything I said here. – Kurt G Harris MD Mar 29 2012 at 4:27
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I just want to tell my story here. I thought paleo was the answer to my diet problems and not just a sticking plaster/band aid. I believed in it, I loved the idea of it and I saw so many people do well on it, though I continued to have problems whilst on it (strictly). And I was always having a nagging feeling about people I saw on raw vegan diets who were doing just as well as those on paleo.

I resent the fact that some paleo people think paleo is the ONLY way to eat, just because it works for them. From my experience, I see it as amazing for some and disastrous for others.

I continued to search; I tried metabolic typing which advocates very different diets according to your metabolism and so far it is the only thing that has 100% worked with me. The beautiful thing is that some people need paleo, some people need vegan, some people need a very broad range of carbs/proteins for optimum health - and many people are on a life long learning curve to try and discover this optimum recipe which is totally unique to each person, based on genetic and environmental factors. My metabolic typing nutritionist has been practising for 15 years and told me everyone who passes through her door is unique and requires an individual diet plan.

I have come a long way on my diet journey, from raw vegan to strict paleo, I have now settled into a metabolically-typed diet which is based on 45% low purine proteins/low fat and 55% low G.I.carbs - and this has hit the spot. This I know now, is not a band aid but a long lasting answer.

I call this my own primitive diet (although it is not what one would call a classic paleo diet by any stretch of the imagination) as I know there was a group of people somewhere in the world (nearer to the equator than I am now) who ate my diet indigenously and thrived on it - they lived in a habitat which matched my particular fuel mix perfectly.

For many people, their 'spot' will be paleo - (varying degrees of strictness) for others it will only ever be a band aid which allows them to move away from a SAD diet and become more conscious of their eating habits. It will be a springboard for further exploration - as it was for me.

As someone else mentioned on this thread, we must continue to be forward-thinking and not get stuck in a rut about all of this, as that would truly be a Neanderthal way of viewing the world and all the myriad people who live within it.

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It may not be as magical as we'd hoped, but eating mostly real food probably isn't going to go out of style any time soon.

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What about WGA and gluten problems in non-celiacs? Is Kurt saying that wheat isn't a NAD anymore, or just that the gut flora is more of the underlying issue? I've always assumed that wheat can cause leaky gut, so it's pertinent to avoid it in novel amounts (a piece of bread a day isn't too big of a deal, but why eat wheat at all?)

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