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Can someone tell me why proline rich bone-broth and gelatin are "good" but proline rich grains and dairy are "bad?"

Explain.

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3 Answers

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Prolamines (proline-containing proteins) are simply a more-difficult-to-digest class of proteins; it's part of the reason that plant proteins digest with an average efficiency of 80-85%, while animal proteins (especially muscle) digests at 90-95%. If those undigested proteins get across the gut lining then you have the potential for immunologic or other biochemistry-disrupting activity (lectins, phytoestrogens, etc). If what's getting across is the free amino acid proline, or smaller, simpler proline-containing proteins (at the level of di- and tri-peptides) then that's benign.

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I think you're confusing proline (the amino acid) with prolamins that are the storage protein in grains. There is proline in prolamins but they are different things.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1131235/pdf/biochemj00186-0010.pdf

A lot of things that have similar names act differently in the body.... glutamate/glutamine/glutathione.... cystine/cysteine/homocysteine, etc

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I know the difference between proline (amino acid) and prolamins (storage protiens) I was just under the impression that gluten and casein ARE problematic because they are rich in proline. We've all heard Mat Lalonde and Robb Wolf harp on about "proline rich proteins" right? – Murph Apr 10 2012 at 20:38
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Even if grains and dairy are rich sources of proline, they can still be bad in virtue of containing gluten, lactose, casein etc. which people are intolerant of.

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