People with high cholesterol levels, defined by a reading of more than 5.8 mmol/L, had significantly more brain plaques when compared to those with normal or lower cholesterol levels. A total of 86 percent of people with high cholesterol had brain plaques, compared with only 62 percent of people with low cholesterol levels.
The study found no link between high cholesterol and the tangles that develop in the brain with Alzheimer's disease.
In addition to high cholesterol increasing the risk of Alzheimer's disease, Sasaki previously found that insulin resistance, a sign of diabetes, may be another risk factor for brain plaques associated with Alzheimer's disease.
Never mind the correlation/causation thing, or that they say serum cholesterol impacts only plaques but then go back to the 'raises risk' thing - my question is whether that last bit is actually the key.
As we know that metabolic syndrome and elevated serum cholesterol are related, and that T2D and Alzheimers are related, is the serum cholesterol number a by-product of a process that actually hinges on insulin?
We've talked around this before; are we ready to call it?