Hello fellow paleohackers.
I am 29, I practice Jiu Jitsu at least 3 times a week, I am in good shape, not overweight and have been paleo since October, LC probably between 50g and 100g of carbs.
Last December I got my blood tested and my TC and LDL were quite high.
TC 6.5 mmol/l = 251 mg/dl Triglycerides 0.7 mmol/l = 62 mg/dl HDL 1.4 mmol/l = 54 mg/dl LDL 4.8 mmol/l = 185 mg/dl
Lately I have also linked something I had been diagnosed for when I was a kid (histamine intolerance (HIT) causing severe urticaria), with some strange symptoms that I had nowadays (constant bloating, occasional diarrhea, sometimes hitching). I then started a low histamine version of my paleo diet which makes things much better (but it's quite annoying).
Now it seems that HIT is caused by low levels of diamine oxidase (DOA), which is a copper regulated enzyme. Jaminet in his book perfect health diet, suggests that the single most common cause of high LDL in low carb eaters is a copper deficiency.
I have now started supplementing copper and I am hoping to solve both issues. Anyone else in a similar boat? What are your thoughs?
It is hard to see if you are copper deficient from labs as far as I know.
Nevertheless if you supplement with a small amount of copper daily you don't even get as much copper as you would if you'd eat liver once a week. My plan is to try to eat more liver and supplement less anyway. Jaminet in fact advises to supplement copper, but not zinc in general.
These are best zinc sources: http://whfoods.org/genpage.php?tname=nutrient&dbid=115
These are best copper sources: http://whfoods.org/genpage.php?tname=nutrient&dbid=53
It's easy to see how a paleo diet is easily shifted towards having more zinc (i.e. beef) and being deficient in copper if you are not eating liver.
Some interesting studies relating copper deficiency and DOA deficiency: Plasma Diamine Oxidase Activity Is Greater in Copper-Adequate than Copper-Marginal or Copper-Deficient Rats ( http://jn.nutrition.org/content/130/1/30.short )
Copper supplementation of adult men: effects on blood copper enzyme activities and indicators of cardiovascular disease risk. http://www.ncbi.nlm.nih.gov/pubmed/9439530
edit #3: Robb Wolf just answered my question on his latest podcast:
He thinks there could be a causation between high LDL (although he says my values are pretty much OK), and histamine intolerance as this could cause chronic inflammation and hence rise LDL cholesterol.