if you already have experience running in them, i think it should be fine. if not, though, you probably want to work up to it to avoid getting injured. depends a lot on what kind of shoe you are sprinting in now. lots of cushion and heel rise?
I too wear my vibrams for walking and working out. I made the mistake recently of running in them without properly learning how to adjust my running style and tore a ligament. Don't do that. Barefoot running is excellent once you learn how to do it properly and have eased into it.
Be careful starting out. I'd try to stick with soft surfaces at first, and slowly build up. I ended up with a stress fracture in my foot because I did too much too fast on hard surfaces. (Ask me how fun that was to deal with.)
Take it slow (REALLY slow) and listen to your body. If I had to do it over again I'd ease in by doing soft surfaces every couple of days, then daily, and slowly adding in bits of harder surfaces.
If it helps at all I barefoot sprint on grass (no vibrams/shoes/footwear at all) without any issues. I'm also weighing in at a hefty 270. I don't tend to have any issues at all. Other than that I'm a fairly lazy dude outside of walking a few KM a week and standing at my desk. Not sure if my personal experiences help you at all.
While I am a big proponent of barefoot running techniques and protocols, I also have played lacrosse most of my life, and I would think you want cleats. I have never thought of playing without them, and definitely notice the difference when playing pick up games in regular sneakers.
We play pickup soccer, and one of the guys wears vibrams (and a couple go barefoot). He switched to a trail running version, and swears by them. Definitely doesn't slip as much as the other guys, but more than those of us in cleats.