I was amused by this post at Paleo Velo. Here's a snippet:
[Another nail in the coffin] of the carbohydrate obesity thesis? Check out Stephen Guyenet’s latest post about a new study that finds that sugar has to be palatable to be fattening in mice. In other words, despite an increase in calories from sugar water, mice whose sugar receptor taste buds had been knocked out did not gain weight like normal mice. Whatever conclusions different people might draw from this study, I think it goes to show that, however fat gain and loss works, it is just a heckuva lot more complicated than the carbohydrate-insulin obesity thesis most recently popularized by Gary Taubes.
The Guyenet post, New Study Demonstrates that Sugar has to be Palatable to be Fattening in Mice, is here.
Dr. Anthony Sclafani's research group just published a study definitively demonstrating that high palatability, or pleasantness of taste, is required for sugar to be fattening in mice (1). Dr. John Glendinning was lead author. Dr. Sclafani's group has done a lot of excellent research over the years. Among other things, he's the person who invented the most fattening rodent diet in the world-- the 'cafeteria diet'-- composed of human junk food.
What do you think of this new line of research? Does it blow your mind? Can we screw with human brains to not taste sugary carbs so that we can all consume crap while staying lean?