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This question came about following a conversation with my housekeeper.

She recently visited a medical practitioner to ask for advice regarding increasing feelings of depression (brought on in my view as a result of her son recently being diagnosed with prostatic carcinoma and being scheduled for surgery). The advice was to start a course of antidepressants and seek psychological counseling.

I explained to my housekeeper that depression is a perfectly normal adaptation (with the exception when it is caused by underlying pathology) which serves to empower the individual to meet challenges in life. In fact, to take antidepressants - a pharmacological quick fix -would deprive her of the opportunity to recognize and address problems that clearly were affecting her.

This is not an unconventional view, see http://www.scientificamerican.com/article.cfm?id=depressions-evolutionary .

Having said that, I do recognize that there are times when a pharmacological intervention is the only reasonable course of action for acute and prolonged bouts of depression.

For paleo people, I it may be that depression could be of particularly concern:

Firstly, the paucity of carbohydrates - especially refined carbohydrates - removes a source of dopamine and serotonin stimulation. This is, of course, beneficial as it hopefully will influence individuals to seek pleasure from healthy activities and suddenly spending the entire weekend in front of the TV will not seem so relaxing.

Secondly, paleo people would be, I believe, disinclined to resort to antidepressants and would seek non-pharmacological methods of balancing serotonin and dopamine. However, not everyone knows what they're doing and some may find themselves suffering for months or longer whilst trying to find the appropriate combination of food and activity.

Can depression be considered as a beneficial adaptation?

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More info on depression: en.wikipedia.org/wiki/Depression_(mood) nimh.nih.gov/health/publications/depression/… – meta Jul 8 at 5:48
I said "yes depression is adaptive" before in my answer. But its a complicated one. Depression may well have spured human discovery, invention, change and growth, but on the other hand, lower mammals and other animals do not merely give up. If a bird gets its foot stuck in ice, it keeps struggling. Giving up completely certainly isnt adaptive, unless it can be transformed back into motivation like other forms of pain. So far as i know, only higher mammals seem to get truely depressed, in the human sense. Only they perform ritualistic behaviour around their dead. – Jamie Jul 8 at 8:30
I think with something so new, the kind of frontal lobe existential awareness that makes us fear and suffer in new ways, its probably not adaptive, it only can be, and only sometimes (such as the person who changes their life, or the explorer/inventor/leader etc). – Jamie Jul 8 at 8:33

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I find this subject so completely frustrating. I think we need a new vocabulary related to this subject. Depression meaning appropriate sadness due to situation or depression caused by brain/body disease? People who do not have the disease have NO idea what it is to suffer and for that I am actually quite happy and grateful. This is something I would not wish on my worst enemy. I am a very happy and positive person (albeit with some attitude) yet I have suffered major depression almost all of my life. I am medicated now and have been for years. I will die taking medication. Major depression is a serious and progressive illness. It is not the blues. It is not appropriate feelings of sadness or loneliness or anger or anything similar. It requires diagnosis by a psychiatric professional not someone who is best suited to dealing with a yearly physical and the common cold. While I might agree that some docs are quick to the pill the social stigma against receiving treatment for any mental illness or issue is so intense and many people who need help are too ashamed or too afraid to get it. I think we need to be careful not to contribute to that. Honestly I can't imagine anyone in their right mind calling major depression a beneficial adaptation and if they did they I hope I'm not in the room when they do.

I have spoken of this before but I have tried several times to get off medication using diet and supplementation to no avail. I am done trying. Paleo doesn't fix everything. Some of us are still going to get sick and ALL of us are still going to die. If you imagine depression did not exist in our ancestors I beg to differ. I imagine there was a very heavy psychological burden living under such brutal conditions. Where did this idea come from that everything was sunshine in roses way back when? Everyone was in perfect health and nothing went wrong with anything ever? A disease of civilization? Hardly.

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Thank you for saying all that. <3 Depression is not my particular problem, but I do have a good idea of what a person with depression goes through. (I want to clarify that when I said I largely agree that depression is a disease of civilization, what I meant by that was that many things about our current civilization seem to aggravate or trigger the condition. I don't believe our ancestors lives were necessarily so brutal - emotionally, I think they probably had a whole lot better sense of security within their community than we do today, and I think that probably helped a great deal.) – Varelse Jul 8 at 5:11
I do hope you realise that drug tolerance means that long term use of anti-depressants actually causes depression. They also cause withdrawl. These effects are exactly like all other drugs. If you dont know about effect reversal, or tolerance, with anti-depressants, it may be something you want to look in to. – Jamie Jul 8 at 6:09
I am always saddened when I hear of people that have gotten into the trap of long term anti-depressant use. Brain receptors when over stimulated down-regulate. When under stimulated they sensitise. They always seek the middle, they adjust. Your receptors will have gotten a work out from the anti-depressants, and basically switched off. Its no wonder you found it so hard coming off them. I am not offering you advise, depression can be terrible "disease" or not, its your life. But I really do hope you do some research into the long term effects of anti-depressants. – Jamie Jul 8 at 6:16
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I've had 'teen' depression, post-MDMA depression, depression from life factors such as lack of partner and job getting me down for periods of time. Depression is terrible and I can see the problem that it is very difficult to fight through it (ie stop medication) because the depression kills the motivation to tough it out and is dangerous. I can say though that since going Paleo I rate my life as more worthless than ever (ie I damn well should be depressed comparing with history) but the chemical imbalance of the past is gone and I'm just OK! – PaleoMouth Jul 8 at 8:54
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Jamie, with all due respect, you have NO idea what you are talking about. It is people like you who spew misinformation like this who perpetuate the stigma. Do I think everyone should be on meds for depression? Absolutely not. But how dare you try to keep people from finding solutions that can save their lives. You should be ashamed of yourself. – Shari Bambino Jul 8 at 16:04
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I have suffered severe depression throughout my life- to the point I have been hospitalized several times. There is a HUGE difference between the sadness, stress and struggle of life and the deep, hopeless dispair of depression. The former can motivate and inspire to change things while the latter feels as though there is nothing you can do about it. Since I have been paleo, life has been good. Is it easy? Am I always happy and stress free? No. However, since I have been paleo, I have been giving my body what it needs to function. Fish oil, good nutrients and vitamins, no grains or dairy to keep my gut happy and allow only the good stuff into my bloodstream. I also work out more (which changes brain chemistry tremendously) and am sure to try and get the sunlight that I can. The energy is there to be able to connect with others, which is also lessens depression. Our bodies know what to do and how to function and make (mostly) what we need (ie. serotonin & other neurotransmitters) provided we give them what, as animals, they need without poisoning them with stuff the is fake and we were not designed to eat.

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After reading that again, that all being said, if depression is bad, many times it takes a lot of support to help a depressed person be able to change habits and thought patterns. Could depression be a catalyst for change? Sure, sometimes. Can depression be deadly? Absolutely. I don't think I would say it is a beneficial adaptation. – Kelley Jul 8 at 10:41
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I've suffered with depression since the age of 13 (now 20) and was diagnosed with bipolar disorder 3 years ago and treated with anti-psychotic medications.

My mood pattern over the last 7 years has been very predictable - 2 episodes of depression a year, one over the winter for around 4-5 months and another usually around a month long in the late spring, both of which followed a brief period of 'mania'.

Last year in October the depression that I presumed was inevitable struck again and I noticed that with it my consumption of sugar and junk fold absolutely exploded. Prior to that I'd been eating the traditional 'healthy' diet (I'd say SAD but I'm British :p) of whole grains, not too much red meat and lots of fruit and veg. I was doing 30mins of strength training 3 times a week and ran 5k 4 times a week. I thought I was living my life in the optimal way so was very discouraged when the depression struck again, and my sugar cravings went through the roof.

Suddenly I was spending £20 a day on junk (crisps, chocolate, cakes, biscuits, fizzy drinks etc.), I stopped exercising and I stopped leaving my university flat (apart from to grab junk food) and stopped interacting with my flatmates. The only human contact I had was with my GP once a week to increase my meds.

The depression got worse and worse (and I assume this now to be a result of my appalling diet and lack of human contact/ sunlight) and eventually in January I was hospitalised (psychiatric) after being prescribed yet another med which made me extremely impulsive and agitated, leading me to come within about half an hour of killing myself.The only reason I'm still here to day is because the psychiatric nurse assigned to me phoned me up to see how I was doing before I managed to put my suicide plan into action.

Once in hospital I was dosed up on benzos and released after a week once I was judged to no longer be a risk to myself. I went back to binging on sugar and avoiding human interaction and was back in hospital a fortnight later. When I was eventually released the second time I was determined to find out what I had done wrong to get depressed again even though according to the medical community I was "doing everything right".

I stumbled across Paleo and dived straight into it. I saw an improvement in my symptoms within a week, and things continued to get better for a few weeks until eventually I felt as good as I had before my first episode of depression when I was 13. I felt clear-headed, alert, my memory improvemed, my motivation returned. I wanted to run and skip and read and laugh.

Despite the vast improvement (I would go as far as to say complete reversal) of my symptoms, my psychiatrist and nurse told me that I was not eating healthily and that they were concerned I was slipping back into my old days of disordered eating like when I was 14 and 15. I was willing to listen to them, so I did an experiment with myself - I went back to the "healthy" eating, and sure enough, back came the fatigue and the lack of motivation, back came the anxiety and the self-doubt. I went back to eating Paleo and my symptoms again disappeared. I no longer even get time of the month cravings or PMS. I feel perfect!

I made the decision to come off my medication and in a months time I will be med-free for the first time in 5 years. I'm being careful not to get too ahead of myself because I know my illness has been a recurrant and persistant one, and that this lifestyle might not be the answer to everything, but deep down I think that this lifestyle is the thing that will save me.

My doctors still look at me like I'm a bit mad when I claim that changing the way I eat, sleep, exercise (lots of walking, heavy lifting twice a week; HIIT twice a week) and relax has fixed every complaint that I had, but I know that it's worked for me so I don't waste energy (or risk causing stress) by arguing with them.

Apologies for the length of this post but it's a topic that I'm really passionate about. My parents are still suspicious of the Paleo diet (at least they have no problems with the sleeping/ exercising/ relaxing part) but they can see a huge difference in me so are agreeing to go along with it for now (though there's no chance as yet of them joining me in this lifestyle, sadly).

To actually answer the question (haha, took me enough time to reach this point) - I would say that once the episode of depression has lifted I do feel more in touch with myself, and it's certainly increased my empathy and sensitivity for/to others. I've become a quieter, more thoughtful person and I think some of that is down to the huge amount of self-reflection that I've done over the years when I was searching for what was going wrong. Whether these qualities would have been useful evoloutionarily speaking, I do not know, but they come in very handy in the present day when studying for my degree because I can take my time with my reading and writing and now I'm Paleo I don't waste dozens of hours a week recovering from hangovers and oversleeping like I used to. ;)

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Interesting thanks for sharing! Choline, which most people lack (even according to standard nutrient authorities, up to 60% of people are lacking), and so do "bipolars", and is found in eggs and meat, has been shown to treat "bipolar" in studies when given as a supplement. Meat is also rich in mood/brain precursors like tryptophan and tyrosine. I do myself wonder to what degree some aspects of "mental illness" is down to diet. Good luck to you, and make sure you keep the sunlight, sleep and human contact up! – Jamie Jul 8 at 12:27
A few select sciency nutritional connections to bipolar and mental illness: Choline - researchgate.net/publication/… Omega 3- ncbi.nlm.nih.gov/pubmed/11780873?dopt=Abstract Vitamins and minerals - psychiatrictimes.com/bipolar-disorder/content/… – Jamie Jul 8 at 12:46
Thanks for the links Jamie. I find the connections between mental health/ the brain and diet and lifestyle really interesting. I think for myself the omega 3:6 ratio has been important so that's something I keep a close eye on too. – Oz Jul 9 at 10:44
Thanks for sharing, Oz. I didn't have that level of depression, but what I did have is so much better on paleo. I tend towards melancholy anyway, but that's manageable. I notice an increase if I have too many cheat-foods... – Joni Jul 24 at 20:05
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I would just like to say that sadness and stress are normal; depression is not. What you have described sounds like sadness and stress, not depression, though since we don't know what else may be going on in this person's life now or in the past, we have no way of telling.

That being said, a lot of times people want a quick fix because they are upset about something going on in their lives, like you said, and the doctor writes the prescription because that is what doctors do, and because many times, if they don't, the person will just go to another doctor until they get the answer and the pills they want.

Depression is a mental illness. Totally a separate thing. (Often over-diagnosed both by physicians and people who like Web MD, IMHO, but that doesn't lessen the gravity of the situation for someone who actually has the disease.) For people who are actually clinically depressed, diet can make a BIG BIG BIG difference, but it is not a cure-all. That person still needs psychotherapy, and possibly medication.

I believe that medication should be a last resort, not the first option, but unfortunately that's just not the way it usually works likely because medication is a lot cheaper than therapy and a lot easier than changing your diet.

I would never judge anyone or give them advice about mental illness, because it is easy to do more harm than you are capable of realizing if that person is mentally ill. If they are mentally ill, you can't expect them to take what you are saying at face value and look at it logically. They may be able to do that; they may not. You just don't know. You just don't know all the factors that could be involved. Mental illness is complicated. I would never, ever tell an individual what to do when it comes to their mental health, other than to see a doctor and wish them the best and let them know I am there for them (if we have that kind of relationship). Even if you are 100% right, it's just not worth the risk, especially when it's not your health you're risking. I can't stress enough how dangerous it can be.

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Anti-depressants cause depression (see my other reply). Bad idea. I am not sure I beleive in "clinical depression" per se. I beleive in paralyzing and self-harmful bad mood. I beleive that can be severe and horrific and long lasting. I dont beleive its an incurable state, tho. I personally was majorly depressed for about 15 years of my life. – Jamie Jul 8 at 6:41
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I do not think that anyone's personal experience, advice, or offer of emotional support should be substituted for a mental health professional's treatment. Ever. No exceptions. If you don't "believe" in a documented disease, then that is something altogether different. It is NEVER worth risking someone else's life to be right. No matter what. – Varelse Jul 8 at 6:52
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If you truly believe in what you are saying - go into research! Go into development! I'm not saying you aren't entitled to your opinions, or that all your points are invalid. But don't be an amateur psychiatrist and endanger the lives and welfare of others. That is just irresponsible and dangerous. – Varelse Jul 8 at 6:55
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If you are encouraging people not to seek treatment, that is not doing good. That is doing harm, and you are playing with fire. – Varelse Jul 8 at 7:01
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I brought up worship because people put an undue amount of trust in doctors and psychiatrists. They usually defer to them rather than get involved. Ive seen plenty of psychiatrists and doctors in my life, and my experience has been that they are very useful, but not worthy of that 100% deference or trust. – Jamie Jul 8 at 7:21
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Depression is often directly linked to systematic inflammation. (I suggest a google search) Though we still don't know the exact link between endorphin production, inflammation, and depression, we do know there is a link.

In addition, certain foods can directly cause the release of neuro-chemicals and subsequent down regulation of neurotransmitter production if they are eaten regularly. Obvious examples are sugar and most processed carbs.

In other words, if your body gets used to "feel good" chemicals coming from food, it stops being as good at making it's own feel-good chemicals. I'm not sure of the mechanism of inflammation's role in depression, but there are plenty of studies out there.

Being sad about something is a natural reaction. Crying even prompts the release of endorphins! But depression is different. It's my belief that being sad about something like a traumatic loss can lead to depression if you are also eating sub-optimally and have chronic inflammation.

There may be other causes of depression other than diet, but with this theory the depression is actually cause by the body's physical response to the stress of a traumatic memory or other mental maladies. In other words, psychology doesn't cause depression directly, rather psychological trauma causes a physical stress response, which if chronic can cause systematic inflammation, which has been linked to depression.

-pete

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Interesting notion. Its doubtful thats all there is too it, but certainly theres more to mood than whats obvious. Bacteria can contribute to mood. People tend to get heart attacks under emotional stress, due to inflammation. Mind you inflammation is kinda a research buzzword ATM, we are probably overemphasizing its role a little bit. – Jamie Jul 8 at 8:43
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Yeah inflammation has achieved a bit of buzzword status. Maybe we are overemphasizing it... on the other hand there are some really interesting studies about ibprofoun (spelling?) Treating depression.... I believe they were double blind etc but haven't read them myself. it amazes me how little we know about the human body – paleopete Jul 10 at 3:39
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Except that depression is a disease of civilisation, so its certainly triggered by unnatural living, such as lack of human touch, sunlight, proper sleep, a lack of sense of place/worldveiw and lack of community, as well as singular events.

But i agree that its adaptive (edit: revised thought, its probably not overall adaptive, even though it can be sometimes as a motivator)

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On the other hand it could be induced by a dependence on refined carbs and then the removal? – Heather Jul 8 at 3:54
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"depression is a disease of civilisation" Really? Citations? – Shari Bambino Jul 8 at 4:42
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This study here, is one of many that links higher income countries with depression - biomedcentral.com/content/pdf/1741-7015-9-90.pdf ...Theres probably some better ones, but I feel half arsed about proving something I personally see as obvious. If you put in "disease of cilivisation"/affluence and "depression", youll hit plenty of stuff to read if your interested. – Jamie Jul 8 at 5:31
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It could also be related to diet. But as I learnt in psychology, subjective wellbeing is strongly linked to three factors: 1) sense of place/purpose 2) community 3) freedom from restrictions. Those first two are more or less completely absent from modern society, especially community, and this makes sense when you compare modern society with natural society. As a psychhology graduate some of this stuff seems obvious to me. The human brain needs touch for oxytocin release. We need small communities because of advantage takers, sense of community and our natural instinct to remember and keep – Jamie Jul 8 at 5:32
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track of only around one hundred people. If you compare ancient ways of life (small tight communties, strong sense of place/connection to the enviroment/philosopy, no touch taboo, lots of excercise and sunlight, natural sleep) with modern communities, from a psychology point of veiw, in the context of depression and mood, I personally realise that we are missing a great deal of basic psychological needs in modern society. – Jamie Jul 8 at 5:37
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My view is pretty much the same as yours.

I think there are times when we need to "lay-low" emotionally, just as we would when recovering from a physical injury.

Having experienced "real" depression, I can tell you that there's nothing adaptive or beneficial about it, but I know there have been other times when I might have shown the outward signs of depression when I felt I was resting or recovering in some way.

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Depression is not an adaptation, it is either caused by nutrient deficiencies (such as B12, choline, zinc, B6, amino acids, etc), or lack of human givens.

Givens are: Security – safe territory and an environment which allows full maturity and development Attention (to give and receive it) – a form of "mental nutrition" Sense of autonomy and control – having volition to make responsible choices Being emotionally connected to others Feeling part of a wider community Friendship and intimacy with someone who is accepting of the total person, flaws included Privacy – opportunity to reflect and consolidate experience Sense of status within social groupings Sense of competence and achievement Meaning and purpose

As you can see our society doesn't provide Givens very well and so we feel depressed, and we use words like 'empty' and 'meaningless' to describe our lives because in a sense they are.

http://en.wikipedia.org/wiki/Human_Givens

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No, I do not view depression as a beneficial adaptation. When something becomes common, like when we all do the wrong thing like eating grains, we tend to think that it is normal. I believe that depression is either a physiological, psychological, or spiritual malady.

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I highly recommend watching the PBS Documentary "This Emotional Life" In Episode 3 titled "Rethinking Happiness" They go into this topic in detail interviewing people with depression, Post Traumatic Stress, Cancer Diagnosis, etc. In the episode they show images of the brain of depressed people and show that the depression actually shrinks the brain. As humans the Fight or flight response is a normal evolutionary response that is actually helpful, however we humans as opposed to animals have no way of shutting off this response and this is what causes things like anxiety and can lead to depression if under chronic stress. I don't think long term depression is beneficial!! In the episode they say something very interesting... They say that people who are happy out achieve and out reproduce people who are unhappy and there are more happy people around now than ever before due to evolution. Interesting and worth watching..

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i don't have much more to say than the amazing responses here, but for me, i beat depression with prayer, focusing on where i am heading/moving forward in life, increasing carbs, and for a while, taking medication.

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i still get depressed sometimes, but it's not the deep hole that it was. carbs were HUGE for me. and taking supplements like GABA. – Rebekah Jul 8 at 19:05

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