Paleo Diet and Paleolithic Diet Questions & Answers

Question

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Has anyone else besides me noticed various condiments effects on symptoms of inflammation?

Case in point: About a week ago I ate eggs with zero signs of intestinal distress or inflammation. A few days later I added black pepper to the mix and noticed that the consumption of both together actually made me wheeze slightly upon breathing and added just a touch of "brain fog". Hot sauce containing red pepper caused a similar reaction as to the black pepper.

So I did a little research finding that egg sensitivity is common in those with leaky gut. The symptoms of this somewhat benign allergy disappeared along with the leaky gut in some.

Intestinal permeability being of an utmost interest of mine, since giving up gluten has helped me so much, I wasn't surprised to find that http://www.ncbi.nlm.nih.gov/m/pubmed/12046863/ - piperine has a deleterious effect on tight junctions and brush border cells. Capsaicin from red peppers does something similar.

I find it interesting that curcumin, which decreases intestinal permeability, is often combined with piperine in the intention to cause a greater desired effect when in fact this practice could result in the very opposite depending on the condition its used for.

Has anyone else come up with similar research on once thought of "paleo safe" additives actually being harmful?

flag	asked Aug 26 at 4:39 dudinator 31●1

Do you have a study at hand which shows the effects of turmeric on intestinal permeability? – Thomy Aug 26 at 8:00

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ncbi.nlm.nih.gov/m/pubmed/18227041 Sorry, I use my phone as my internet source most of the time and multiple copy/pastes in a single post are tedious and I'm lazy from all that egg/piperine combo. – dudinator Aug 26 at 12:09

Hi, I just read thru some studies again and I wouldn't say, those spices increase intestinal permeability but rather the absorption surface. piperine, curcumin and all the othger spices do somehow increase villi size und crypt depth, which promotes nutrient absorption. If you're allergic this larger surface will also make contact with allergens more likely. What do you think? – Thomy Aug 27 at 14:42

Thomy · Answer 1 · 2012-08-26 07:44:29Z UTC

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Yeah, I'm allergic to dairy, but I can tolerate ghee well. This totally changes when I add capsaicin containing spices. Haven't tried pepper yet.

answered Aug 26 at 7:44

Thomy
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matthew · Answer 2 · 2012-08-28 04:28:04Z UTC

In order to have a strong reaction from food you need two thing to meet in your intestines within certain time 1. agent that promotes leaky gut AND 2. foods that can cross the intestinal barrier to your bloodstream and cause inflammation and/or immune system reaction

Hot spices (www.leakygutresearch.com/hot-spices-leaky-gut/) fall into the first group, eggs into the second.

I know of another combination that when consuming the foods alone is harmless, when combined gives me a reacion: coffee (www.leakygutresearch.com/leaky-gut-and-coffee/) and milk.

CICO Suave · Answer 3 · 2012-08-26 07:55:23Z UTC

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I don't know about effects on intestinal permeability, but I know they've been PROVEN to reduce the risk of most STDs - to say nothing of preventing pregnancy. For that reason alone I think they should be made widely available to ANYONE who is sexually active. Just sayin'.

answered Aug 26 at 7:55

CICO Suave
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wtf are you talking about? – raydawg Aug 28 at 10:11

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Get a sense of humor, dude. – CICO Suave Aug 29 at 2:10

Condiments Effects on Intestinal Permeability

3 Answers