Paleo Diet and Paleolithic Diet Questions & Answers

Question

6

http://www.ncbi.nlm.nih.gov/m/pubmed/19433800/

As we know, exercise increases insulin sensitivity. This study says vitamin C and antioxidants negate that effect.

Apparently it shuts down the benefits of autophagy too. http://metamodern.com/2010/09/26/antioxidants-block-cell-repair/

So does this mean we should not take Vit C?

Or should we time intake appropriately? The study doesn't mention timing. I wonder if taking Vit C at night, long after exercise, and not during the autophagy phase of a fast, would help?

edited Sep 11 at 10:01

asked Sep 11 at 9:41

animaleater
3,268●11●32

JayJay · Answer 1 · 2012-09-11 19:53:47Z UTC

Very interesting. I think this "I’m sure that there are further insights (and corrections) that can be extracted from the literature in place today, and I look forward to seeing that literature itself become half-obsolete next year." says it all though. For the time being I will stick to vitamin D and magnesium as my only supplements.

The problem with vitamin C at night is that ....well that is exactly when you are fasting. If you wanted to time it, it would seem taking it with your meals only is your best bet.

miked · Answer 2 · 2012-11-06 23:33:20Z UTC

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Yeah, this is pretty well known in the exercise community. Antioxidents blunt the hormetic stressor that exercise provides so you actually don't get the benefits from the exercise. Even ibuprofin PWO will limit the benefit you get from the workout.

answered Nov 6 at 23:33

miked
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	Do antioxidants stop the non-insulin mediated glucose uptake process which is stimulated by training? (GLUT is mobilized to the surface of muscle cells to take sugar in without insult to stimulate the process) ?? – animaleater Nov 7 at 5:59
	Without INSULIN (not insult, lol) – animaleater Nov 7 at 6:00
	I would inagine there no/little effect. The hormetic stress of exercise is the oxidative damage that results from all of the free radicals created during combustion. That's what the antioxidants undo. – miked Nov 7 at 16:12

Antioxidants (Vitamin C) stop exercise induced increased insulin sensitivity

2 Answers