I have experimented with various macronutrient ratios and my skin is virtually flawless when I am eating mostly carbs and fat, and a very low amount of protein, generally about 3-4 ounces a day. I have tried this with grass-fed beef and grain-fed beef but the results are the same. The more protein I consume the worse my skin looks. I know there are a lot of people who could eat all the protein in the world and not notice a difference in skin quality, but how about those with damaged guts? Is it crazy to think that people that have damaged their guts might be reacting to otherwise benign proteins from chicken, beef, and fish? Does anyone with an any type of autoimmune disease react negatively to a high protein diet? Do we fix this problem by eating mostly carbs and fat until the gut is healed?
I actually react to high protein meata as well. I do have Leaky Gut also, but when eating concetrated protein (chicken/pork) I get extreme brainfog, cortisol increase and bloodsugar drops. A couple of years ago this never happened. Have very skin though and eat pork twice a week.
Whether or not leaky gut plays a part, I don't know. Low, but adequate, protein is something that is probably a good idea though. It's quite likely that the calorie restriction/longevity correlation due more to protein restriction/moderation rather than energy restriction.
No. I have an autoimmune disease (psoriasis) and I have no problem with meat of any sort. AFAIK, protein fragments slipping through a leaky gut only cause problems if there is molecular mimicry with human proteins, thus causing the immune system to develop antibodies to attack these "invaders". This is true with casein, a protein in dairy; I developed a severe sensitivity to dairy past age 50 most likely in part to having a leaky gut. Other proteins can be involved:
However I don't believe molecular mimicry has anything to do with animal meat. Having said this, I do know of people with psoriasis who experience a worsening condition when eating meat. I suspect there are complex reasons involved versus it being a molecular mimicry/leaky gut issue.