Currently I am not having any supplement, but two substances raised my interest: co-enzime q10 which is produced by the body but its production diminishes with age, to the extent that some people believe that it is one of the substances that drives aging at the cells level http://www.yourhealthbase.com/coenzyme_Q10.htm and also vitamin k2 that also has great qualities, being a key factor in the prevention of osteoporosis and vascular Calcification http://www.suite101.com/content/can-anything-cure-vascular-calcification-a155895 while often not found in sufficient quantities in our food intake, unless you consume unrealistic amounts of eggs or milk.
Do you supplement with any of these substances, or have you thought about them?
If, like so many of us, you are not lucky enough to have a source for pastured/grass-fed eggs, dairy and meat then you need to learn to love natto to get K2 into you diet. Even if you can get pastured products the K2 content drops to almost nil in the winter time, so other sources (natto or a supplement) are necessary to beat that seasonal trend.
As for CoQ10, as long as you are eating heart and liver regularly (once every couple of weeks at least) you don't need a supplement. Otherwise, you do.
I eat copious amounts of pastured butter, and thus consume large amounts of mk-7 k-2. I also eat natto on most days and as a result get pretty large amounts of mk-4 k-2. I would wager that one or the other would be sufficient for good health. I'm not convinced that coenzyme Q10 is necessary with our diets.
As far as supplementation in general goes, I do 5000IU for about 1/2 to 2/3rds of the year (high latitude) as well as 3 grams of vitamin C per day. Correct vitamin D levels necessitate correct vitamin k and vitamin A levels. People who supplement D (and presumably those who get a lot of sun) and don't get enough k-2 run into calcium issues. As far as the vitamin C goes, the research I've done indicates that ascorbate increases the excretion of urate, which has various deleterious effects ranging from high blood pressure to kidney disease. It's unlikely that a low-fructose diet would produce sufficiently high uric acid levels to cause problems, but lower uric acid in general is likely desirable.
For people with moderately high blood pressure, CoQ-10 is probably much preferable to pharmaceuticals. It definitely helped me out, as part of my healthy eating and exercise regimen my BP has been reduced about 20 points sys/7 points dia.
pastured dairy provides plenty of k2, specifically butter, ghee, raw milk, cream. if you can't do dairy foods, try high vitamin butter oil as a supplement. even people who cannot tolerate casein/lactose can almost definitely tolerate hvbo, as there is virtully zero lactose and very little casein.
great info...one thing though, according to my doc, our bodies don't convert vitamin D from the sun any longer, so we all need vitamin D. It is one of the things that we need every day. My husband was recently diagnosed with a vitamin D deficiency, it was sore limbs, neck pain, no energy, tired, etc. Took a vitamin D drop that he got from the natural doc, which amounted to 4000 units a day, but went directly into the body through the mouth, not the stomach. In four days he was feeling alot better. Just hoping this info helps someone. :)