Paleo Diet and Paleolithic Diet Questions & Answers

Question

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I have read a bit about how ketosis improves brain function via production of some hormone, ligand, or something along those lines.

I am interested in what exactly is going on to cause this, as well as, the biochemistry behind it.

If someone knows of a credible link and/or information resource, a study in regards to this, or anything else pertaining to it, would you please post a link. (And, if you would like to explain it, that would be great too.)

edited Apr 7 2011 at 11:17

Adam Crafter
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asked Apr 6 2011 at 11:42

Allie
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	Hey Allie. You seem to respond to the same kind of questions I would. What's your reason for going paleo? – Rud May 8 2011 at 3:29
	Heya Charlie- mmm, mostly it seemed to make a great deal of sense. Paleo is supported by research and through self-experimentation I have personally seen its impact. I had some chocolate yesterday and got quite ill later, come to find out it had traces of gluten! -.- – Allie May 10 2011 at 16:07

Dave S. · Answer 1 · 2011-04-06 13:08:34Z UTC

Basic idea is that ketones provide fuel to brain cells that are not functioning well on glucose. Some Links:

http://evolutionarypsychiatry.blogspot.com/2010/08/your-brain-on-ketones.html

http://evolutionarypsychiatry.blogspot.com/2010/08/ketogenic-diets-and-bipolar-disorder.html

http://evolutionarypsychiatry.blogspot.com/2011/02/food-elimination-diet-and-adhd.html

http://high-fat-nutrition.blogspot.com/2008/12/alzheimers-and-ketones.html

http://high-fat-nutrition.blogspot.com/2006/10/parkinsons-disease.html

http://www.drbriffa.com/2011/03/29/carbs-are-bad-news-for-the-brain/

The Quilt · Answer 2 · 2011-04-06 13:44:50Z UTC

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Oldy but goody

Metabolism of Ketone Bodies by the Brain Annual Review of Medicine Vol. 24: 271-280 (Volume publication date February 1973) DOI: 10.1146/annurev.me.24.020173.001415
Brain energetics: integration of molecular and cellular processes edited by Gary E. Gibson Great book!

answered Apr 6 2011 at 13:44

The Quilt
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	Thanks Dr. K, I'll see if my library has them or if I can get them cheap of Amazon. I recently bought a biochem book to learn more about our physiology in general but I don't think it is geared toward the process I asked about. Thank you for the suggestions! – Allie Apr 6 2011 at 18:53
	allie you are smart to do so.....the more knowledge you have the more you can help your doc be a better health care advocate for yourself. I just hope docs are more receptive to an open relationship. I love patients that are engaged and excited to retain their health – The Quilt Apr 7 2011 at 1:56
	It also helps that I want to be a naturopath too ;). I just want to start learning about it all now. – Allie Apr 7 2011 at 11:28

Adam Crafter · Answer 3 · 2011-04-06 15:38:49Z UTC

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http://www.phschool.com/science/science_news/articles/ketones_to_the_rescue.html was a fun read for me. It also talks about ketones effects on the heart.

answered Apr 6 2011 at 15:38

Adam Crafter
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	Thanks for the link Adam, I'll give it a more thorough read later this week. I appreciate the link. – Allie Apr 6 2011 at 18:54
	Do you just have access to the public items, or do you have some sort of school access for the papers that are subscription only? – Adam Crafter Apr 7 2011 at 11:15
	I'm sure I have school access via my University (well, at least until May). I'll try to look into it. Though, I also like having a 'hard copy' to keep in someway. Again, thanks for the link. – Allie Apr 9 2011 at 12:49

Biological mechanism that improves brain function during Ketosis

3 Answers