Paleo Diet and Paleolithic Diet Questions & Answers

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Just had our baby boy, Friedrich "Fritz" Ward Rangitsch on the 15th. Fed up Paleo (85%) from before conception (41 year old Pop, 38 year old Mom). A very Paleo/Primal experience from start to finish.

My question is on PKU since it has been a topic for me of late. Not looking for a debate, or even to share our decisions in any of the vaccine/testing of a newborn.

PKU is the rare inherited reduction or complete lack of an enzyme to metabolize an amino acid, and can lead to a "poisoning" from that amino leading to neurological problems, etc. Seems the CW take is to follow a PKU diet that eliminates just about all protein, eliminated soy, seitian, red meat, eggs, milk, etc. It has occurred to me that the CW take to solve gout is to eliminate red meat and meats high in purines, when in reality Gout is mediated/cured by the elimination of fructose and reduction sugars in general. The CW take is to see all the excess purines and then move to eliminate them in the diet, but is it cause/effect or is the causality reversed? Our diets are very high in fat (70%+) and Fritz's is up there as well (breast feeding, so the natural proportions there)

As such, could PKU be of a similar bent? Perhaps the "cure" to PKU is to keep out such nasties as Aspartame, soy, setian.... which we will do as a matter of course, nothing whatsoever to do with PKU.

flag	asked Apr 17 2010 at 15:36 Tim Rangitsch 4,803●1●7●17

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I would make sure to supplement or use a formula that contains DHA ncbi.nlm.nih.gov/pubmed/19615874 when your son is no longer breastfeeding. Other supplements that might be beneficial would be taurine and CLA, which seem to be under-appreciated in CW. – Bread-Eating Beelzebub Apr 17 2010 at 16:57

This is one of those rare times when I disagree with Melissa -- I say stay from formulas at all times. – Patrik♦ Apr 17 2010 at 20:55

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If he actually had PKU, formula is kind of the only option. In paleo times, people with PKU died. – Bread-Eating Beelzebub Apr 18 2010 at 5:09

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I must also speak up here to say that there are times when formula is necessary. As a mother who suffered from low milk supply twice (due to hypothyroidism), I can say that the demonizing of formula by well meaning people and organizations made me feel like I was poisoning my children when I was just doing what I had to to feed them. Breast is absolutely best, but don't judge 'til you've been there. – Mama J Apr 18 2010 at 15:30

Tim, I'm father of a PKU. Please, please, plesae DO screen your baby!!!! It has nothing to do with paleo, grains or anything else. PKU is a rare genetic disorder that was unknown until 70s. Video here_ youtube.com/watch?v=SPzA-UD8Vx4 Phenylalanine is not properly metabolized and it acummulates in brain and nerve tissue provoking mental retardation. The only way to treat PKU now is avoiding proteins, supplement aminoacids, and consume carbs and fats. – Nirgal Dec 19 2011 at 14:40

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Matt · Accepted Answer · 2010-04-17 19:14:20Z UTC

Congratulations on the birth of your son.

This is a situation in which to be very thankfull for modern science and medicine and the screening of newborn babies. The genetic mutation has been around for a long time and is present worldwide although Phenylketonuria is rare. Fortunately it is now known that avoiding all dietary sources of the amino acid phenylalanine prevents the negative consequences, in a similar way to avoiding all gluten in celiac disease, however much inconvenience (a lot) this creates. This has to take priority over any other food choices, sufferers of PKU are unfortunately the rare cases for whom meat, fish and eggs can be completely toxic.

Babies born without this enzyme at any time in the past suffered terribly from it. However by following your doctors adicve carefully PKU children can grow up just fine. The science on rare genetic problems is much clearer and more certain than that on general food and health (such as Gout).

Diet or environment is not envolved in causing mutations like PKU, they are simply a an occasional faulty result of the way our DNA works.

Best wishes to you both and your son.

Dexter · Answer 2 · 2010-04-17 23:17:52Z UTC

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Jimmy Moore reports from a Low Carb Conference in Seattle today that groups of people whose traditional native diet consists of mostly high fat grow maybe 5 inches taller than groups that eat mostly grains and carbs.

Masai are tall and healthy and a neighboring tribe eating grains are 5 inches shorter.

Fritz is going to be a giant. Sign him up for a multimillion dollar NBA contract!

And keep Fritz on breast milk for at least 3 years. There is no paleo formula!!

Contratulations on the birth of your son!

answered Apr 17 2010 at 23:17

Dexter
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This might be a topic for another line of inquiry! But certainly we shall see if the epigenetic/genetic influences, the sins of the father (and grandfather, and great grandfather) are so easily reversed! Pottenger's cats re-played in my own flesh and blood! I am certainly counting on the best gene expression I can give the lad! And thanks for the well wishes, all! – Tim Rangitsch Apr 18 2010 at 1:16

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I am doubtful that epigenetics from parents plays a big role in humans. Influences directly in the womb are more likely. Traditional eskimos ate alot of fat and weren't tall. Average male height of 5 foot 5 inches in the 1930's. jn.nutrition.org/cgi/reprint/18/4/361.pdf If you want be really tall drink lots of milk with its natural growth hormones like the Masai and the Dutch do. ajcn.org/cgi/content/full/80/4/1088-a – Matt Apr 18 2010 at 14:09

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We are just planning to give him the best start. He's had that since before conception and will be on going. Mother eats as "clean" as I can source, game meat, range-fed beef, wild caught trout, eggs, veggies, raw milk/cream/butter from natural/local producers. I wonder if Fritz can have a broad face, wide jaw, good teeth, eyesight, sinus etc rather than being a skinny faced, crooked toothed, nearsighted mouth breather like his Pop! – Tim Rangitsch Apr 18 2010 at 15:32

I think it is highly likely that he can :) – Matt Apr 18 2010 at 15:36

Phenylketonuria, PKU

2 Answers