I seem to be having hypothyroid symptoms even though my blood work seems to be fine. Here're the results along w/some relevant metrics:
- 10/01/09 TSH (0.81)
- 10/27/09 TSH (0.75); T4 (1.25); Cortisol (14.3); Testosterone (307); Homocysteine (8.7)
- 12/31/09 TSH (0.52); T3 (2.60); T4 (1.13); Cortisol (14.1) Testosterone (466); Free T Dir (14.7)
- 04/26/10 TSH (1.47); T4 (1.25)
- 09/09/10 TSH (0.70)
- 12/10/10 TSH (0.60); T3 (3.00) T4 (1.66)
Obviously my TSH is low and below the functional range (1.8-3), so I don't seem to be hypo and in fact hyper. My T3 and T4 seem normal. However, here are my hypo-like symptoms:
- Cold fingers & hands (but toes aren't cold)
- Chronic constipation for 2Y: lack of colon moisture & Bristol Chart 1 stool (tried pre/probiotics, fermented food/beverages, soluble fiber supplements, as well as antioxidants and starch introduction a la PHD).
- Dry, scaly, cracked feet: mounds of dead skin when going barefoot (hands aren't dry though)
- Irregular, brittle, fungal & whitened-out toe nails
- Low libido: testosterone (see above) seems low.
- Skin rash / psoriasis, calf area. Not too itchy but been there for 2Y.
- Forgetfulness and senior moments: nothing major but it's sometimes confounding when you can't remember the names of your coworkers.
However, no real
- Fatigue, sluggishness or depression
- Increased sensitivity to cold
- Hoarse voice
- Muscle weakness
- Brittle hair
- No real IBD/IBS or digestive issues other than constipation
- No weakened immune system for chronic infections
I'm currently seeing an endo and rheumy for T2 diabetes and autoimmune issues: (i) Sjogren's (confirmed) and (ii) occasional gout-like joint attacks (not confirmed to be gout or rheumatoid arthritis, however). I've been eating low-carb/Paleo last 2 years. My BG control is ok (A1C: 5.4-5.7), as is my weight (5-10/157, 46Y male) and my autoimmune symptoms have improved since Paleoing. I do low carb (50-75g net carbs; 65% fat, 20% prot, 15% carbs) and am intermittently ketogenic. Never been tested for thyroid antibodies.
What do you think? Is this what Chris Kresser would call "hypothyroidism caused by pituitary dysfunction" or "thyroid resistance"? However, my cortisol and other measures (e.g., homocysteine) seem normal.