Or is this forum so good that everything has been covered?
Wow, this is the first time I've been called out to answer a question. From a doctor's perspective, I think it's important to remember:
Your doctor is not the boss of you. The old school model of authoritarian medicine is dead (unless that's what you want).
You (as a member of PaleoHacks) probably know much more about nutrition than your doctor. Medical training typically includes little about nutrition, much of which is wrong. The reason that luminaries such as Drs. Harris, Eades and K are so knowledgeable is because of their own personal interest and efforts beyond their training.
Conventional wisdom is sometimes right, as discussed in this recent thread.The trick, of course, is figuring out when or when not to follow CW.
You should be as skeptical about alternative medicine as you are of allopathic medicine. Placebo effects abound in all forms of therapy. Ask yourself whether the proposed mechanism of action makes physical sense.
Medical organizations are usually late adopters of innovations. For example, I attended a Q&A at a prenatal class yesterday. The nurse who led the class, as well as all the parents-to-be, knew that 200 to 300mg per day of DHA was a good idea for pregnant and nursing mothers. Yet, neither ACOG (American College of Obstetricians and Gynecologists) nor AAP (American Academy of Pediatrics) has officially taken a stand on DHA supplementation during pregnancy and nursing.
The more meat you eat the more iodine you are required to have to convert T4 to T3.......a big reason for plateaus....
There seems to be a strong positive correlation between high levels of stress hormones and free-radical damage, and both of these correlate negatively with level of telomerase expression and lead to serious disease states.
It is not enough to avoid omega 6's grains dairy and fructose and still think this is paleo.......the situation of the host immunity and evolving gut health is always the most important thing to long term viability. If that is intact the host can get away with a lot more than one thinks.
You need feedback from your body to know what paleo really means for your internal metabolic machinery and this answer does not translate to a population......it has a very custom effect. We can draw conclusions from 30000 ft view but there are no rules on what defines paleo for any one person. Context matters.
Green tea.....another very paleo thing not talked enough about here. Green tea blocks aromatase enzyme so it increases the sex steroid hormones. Moreover,L-theanine is derived from green tea and crosses the blood-brain barrier. It promotes expression of the neurotransmitter seratonin. There is evidence that l-theanine is neuroprotective, and that it supports relaxation and enhances cognitive function. It appears to decrease the transmission of stimulating neurotransmitters while promoting the transmission of calming neurotransmitters.
Another thing I ask my younger paleo's to do is this......maximally eat to protect your brain before the age of 30.....You have to protect you NMDA channels and you must protect against glutamate toxicity in the brain. Excitotoxins destroy the real controller of our metabolism and that is the hypothalamus. Avoid aspartame MSG and sucralose and saccharin at all costs. And if you have used a ton reverse and protect what is left with N acetyl cysteine, tumeric, resveratrol in as high a doses as you can afford. Obviously this is a bigger focus in older paleos i treat but this is huge for young
I find it interesting that all of the major risk factors associated with cardiovascular disease (obesity, smoking, poor lipid profile, high blood pressure, diabetes and psychological stress) are associated with key markers of cellular aging (shorter telomere lengths, reduced telomerase activity and higher oxidative damage. That tells me that telomere length is a great measure of what is un paleo......in a sense. Since checking for it is too expensive I use ultra sensitive CRP as a proxy for it because we know it shortens telomeres. Cortisol is another biggie and why I am not a cross fit guy
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