Let's say an obese individual loses a bunch of weight. From what I know regarding Leptin, (which isn't much, I'm workin on it...) said individual should have lower levels of Leptin as a result of the weight loss. At what point, if at all, does lower Leptin level have deleterious effects? i.e. down-regulating certain bodily functions?
Could this be a factor in why body builders who have such low body fat levels, have reproductive issues?
Taking this further, if one who is more interested in maintaining sub 10% BF levels (which I think may not be ideal for optimal health, but definitely takes your swagger up a notch) Would carb re-feeds intended to reset leptin levels be almost necessary, for overall health?
Edit: Added Link to a study that touches on this