I feel that I understand this and this is the paradigm of nutrition that I used while practicing clinical nutrition earlier in my career. I was able to help people using this paradigm, but I no longer use it. While you can help people within this nutrigenomic paradigm, it misses the mark. This paradigm states that each of us is SO SPECIAL and SO UNIQUE that we need a customized 'this' or a customized 'that'. But it basically is nonsense if you are seeking optimal health. The ideal human diet (whatever it is) is species-wide and species-specific. Each human of course, should strive to achieve the most ideal modified-paleolithic-diet. Now, it is worthwhile to debate what exactly constitutes an ideal modified-paleo-diet in a non-paleolithic world, but there is only one ideal diet for 'all' humans. This is what every other species on the planet does. Diets are species-wide/species-specific, other mammals do not demonstrate the need for special 'meals'. BTW, according to Boyd Eaton, humans are one of the least genetically-diverse of the mammalian species. Gorillas, for instance, are much more genetically-diverse (among there own species) than humans. NO OTHER (non-domesticated) mammal species demonstrates "individuality" with respect to diet, yet we stubbornly and falsely believe that each of us has intricate and special physiological needs in order to achieve optimal function. It is not so! It is important to note that the medical industry will do everything in its power to maintain control over your health. Just like religions have said throughout the ages: "The way to heaven is right through these church doors" the medically industry has most people convinced (and most people on this board too, IMHO) that health is just not possible without the assistance of their special (blood, saliva, DNA) tests and interventions at every turn.

Finally, while the following is true: Different individuals will respond differently to the chronic exposure to the ubiquitous sub-optimal (toxic and deficient) dietary environment (aka the standard American diet), i.e. some will develop cancer, some will accumulate a lot of fat, some be diabetic, some will develop cardiovascular disease, etc....this has NO BEARING on the fact that what is IDEAL (dietarily) is the same for all (nearly all) humans. Cheers.