I think it makes a lot of sense. Farming a]forces permanent settlements, which vastly increase filth, diseases and parasites, as well as changing cultures profoundly (one aspect that seems to be constant is promoting the idea of women as property which leads to earlier marriage of girls) and b]provides a grain-based diet that is much less nutritious and high in starch. Which leads to earlier puberty and more-frequent births, causing a population explosion while at the same time decreasing the quality of our offspring from gestation onward. With poorly-nourished mothers, often starting when they are just past puberty to give birth every 1-2 years instead of every 3-5, fetuses have less maternal nutrient stores to draw upon, and babies and children get poorer care, as well as having to survive on sub-optimal grain-based diets, in dirty conditions, and at constant exposure to disease and parasites. While mothers are are at vastly increased risk of birth injury and death, and are often, physically, very run-down... as well as having stunted growth in some cases from child-bearing while they themselves should be still growing...
ETA: I also think the theory that being a hunter-gatherer promotes higher intelligence is sound.