Are you it's a blister and not a little zit? I ask, because I got one a few years back - it had a name (no, not Henry or anything - a medical name) and piercing it then using tea tree oil worked a treat. No antibiotics needed...

My first line would be topical iodine.

As to the broader question, it could be a sign of vitamin or mineral deficiencies. Do you supplement?

I would take the bandage off so your wound can breathe. The fresh air will keep the blister and the surrounding area dry and clean. Make a salt-water solution and wipe your heel down gently then take a look. If it doesn't look quite as bad as you thought do a thin layer of triple antibiotic cream/ointment or tea tree oil if you would rather try natural. Hydrogen Peroxide definitely kills the bad tissue but unfortunately it also kills the live tissue - that's why you'll get white edging around a wound if used - that's now dead tissue. Too many hospital visits taught me that one :) You can still use it but dilute with water so it's not quite so damaging. I know that a weakened immune system makes itself known with rashes, blisters and such.. and eczema can appear in different forms, a gf gets blisters instead of the itchy scaling/rash, and your Doc would have said if your last infected blister was staph. I've read that having too much of of a certain vitamin in the body can cause some serious chain reactions but you're eating healthy and probably getting the bulk of your vitamins from nutrition rather than supplements. I wish I had more to help, but whatever you find out I hope that you give an update so we know the answer to this mystery, painful that it is. Be well!

For me, echinacea and goldenseal (sold together in capsule form) works in less than 24 hours whereas antibiotics I have been prescribed always take weeks to work not to mention all the other side effects.

I use to have alot of infections around my finger nails, ok, I'm a nervous nail bitter. For some reason they were really bad for a while when we moved into our new place, they would get hot and red and swollen and feel infected. It was a constant occurance, and yes I wash my hands meticulously with anti-bacterial soap alot!

Now, this is gonna hurt. What worked for me is pouring peroxide onto the wound. Let it bubble and get in there. It will sting the first few times. Then use neosporen cream (also has some sort of pain relief).

do the peroxide treatment 2x day/day-night. the skin will kind of toughen but you should feel some relief (if its not bubbling its cleared up the infection) Do the neosporen cream several times the first few days and really get it in there.

Since were' talking about the bottom of your foot its a hard place to not bump or put weight on. I'd baby it for the next few days. (I'd give this a try before antibiotics)

hope this helps!!

Back when I got my navel pierced, the recommendation was salt on a hot damp washcloth. I found putting the washcloth in the microwave for ~30sec would get it hotter than tap water and it would stay hotter longer. The salt helps draw out the infection.

Peroxide is good for an initial wound cleaning but it also kills good bacteria on your skin and can actually hinder healing.

+1 on the neosporen cream with pain relief.

on the bottom of your foot, keep it covered with a bandaid and keep socks and shoes on.

are you sure there is nothing stuck in the wound? (splinter, glass, etc)

I think you should go to the doctor. Infection is nothing to mess with, and the bottom of your foot is a hard place to try to treat yourself. Recurring sores in the same area (your foot) sounds like it might very well be staph or some other (maybe worse) resistant bug.

What kind of health care do you have? If it's possible, I'd suggest you go see a wound doctor. Wound doctors work exclusively with resistant, recurrent infections, and they really know how to dress and treat wounds caused by things like staph and MRSA.

Do you know your vitamin A and D status? Do you supp A and D or make sure to get enough naturally?

Do you get enough vitamin C?