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How long does it take before you see weight loss?

How long does it take before there are signs of becomeing leptin sensitive?

Are you seeing results? Side effects?

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Can you provide a link to his suggestions? I'm not familiar with them. – turkeytyme Jul 24 2011 at 10:18
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Mentioned first on this post, I think jackkruse.com/… Then spelled out here jackkruse.com/my-leptin-prescription – Glither Jul 24 2011 at 10:31
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marksdailyapple.com/forum/thread32345.html – The Quilt Jul 24 2011 at 11:53
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I know there has been a lot of criticism toward Dr. Kruse's blog as far as editing, flow of words, technical language, etc., but I for one have been enjoying it very much. I hope he reads this comment... loved his interview and loving the blog... thank you so much Dr. Kruse! – Jamie G. Jul 24 2011 at 21:12
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i did read it Jaime.....thanks. Criticism is my epigenetic switch. You can choose to get lost in many issues. But based upon the hits and the emails I think I'm starting to do something right. People are sick and getting sicker and very few are helping. Some see a glimmer of light where others see bad writing. Me.....Ill keep going because it feels right to do so. – The Quilt Jul 26 2011 at 0:54
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11 Answers

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I didn't stumble upon The Quilt until I was fully Leptin Sensitive. I went through all the stages he claims would happen. At 42, I'd had sleep apnea for years w/o treatment, got fat, was put on meds for hypothyroid, high bp, high trigs, gout, and almost diabetes meds, too. I had non-alcoholic fatty liver disease and joint pain. I ate total crap SAD. Once I got the CPAP I started sleeping better, but not great. I lost a little weight but was still eating crap. I started paleo and exercising by lifting heavy things--that's when things started happening. I sweated more, I was waking up at 6am before the alarm clock with morning wood to make a teen proud, I was losing weight like crazy, I was able to skip meals without being hungry, I was able to quit counting calories--they don't seem to matter anymore. Best of all, I'm off ALL medication and look and feel great!

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go akman!!!!!!! – The Quilt Sep 15 2011 at 16:49
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I just finished week one of the protocol.

It's really hard at first. I woke up the first day and was still full from last night's dinner. So I dutifully ate 50g of protein while full. sigh

The next day was a bit easier, but still felt like a lot of work.

By the end of the week, I started noticing a bunch of different stuff that I can only chalk up to my eating hard-core paleo and the protocol.

-I was hungry in the morning

-Didn't have cravings

-Had more energy

-Skin started clearing up (even more than when I first went paleo)

-Lost 10 pounds (probably as much the protocol as it was going under 30-50g of carbs a day)

I'm currently on day 8, and plan on doing 8 weeks of it, through November 2nd. After that, I'll post a "review and thoughts" on one of the primal/paleo forums.

I'll then buy a blood glucose meter and start figuring out how many carbs I can eat. Provided that I actually hit the point where I'm "leptin sensitive". Worst case, I keep up the protocol through February or March.

Note: I am taking 200mg HTP-5 in the morning, and magnesium at night (natural calm) to help deal with cravings and to reset insulin sensitivity. I'm going to use the HTP-5 for another week or two, and then it'll be just the magnesium.

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Had a lady come up to me at the hospital when I came out of surgery......she was one of my former spine patients. 14 months and 102 lbs down. 5'4 at 122 lbs. And no back pain. That made me smile – The Quilt Sep 14 2011 at 22:13
That's cool. I don't have any back pain, but I'd like to get rid of the extraneous fat. It would be a LOT easier to move around :) – Jake Sep 15 2011 at 7:41
Skin started clearing up?? I'm gonna give this a serious try! Any place I can get examples of meals? – Korion Sep 15 2011 at 15:29
Hmmm...I tend to eat a lot of eggs/meat/coconut/butter. Those are my go to. For the 50 grams of protein in the am, it's 5 eggs + 4 oz meat or more bacon. jackkruse.com/the-leptin-rx-faqs jackkruse.com/my-leptin-prescription – Jake Sep 15 2011 at 20:15
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Yes... been doing about 50 to 75 grams of protein every morning for breakfast... staying at about 50 grams of Carbs a day (doing about 150 to 200 grams of protein, I'm lifting and trying to build muscle mass).

I eat three times a day (0630 hrs., 1100 hrs., 1700 hrs.), full-on paleo (though I do eat some cheese and occasionally drink milk with my protein shakes). I'm still dealing with a sweet tooth once or twice a week. I also lift weights three times a week (one hour sessions), cardio class two times a week (one hour sessions), and do HIIT three-four times a week (20 minute sessions). I sleep great, feel great, and am seeing great strength gains. I don't want to quit my cardio because I have a physical agility test coming up for a prospective employer.

I can't say I've seen much change. I had lost 60 lbs. calorie counting (before going paleo) but gained back 25 lbs. since Jan '11 trying to build back muscle mass. I don't care about losing weight, but I'd like to lean out and lose the skinny fat around the abdomen. I do drink whey protein shakes after workouts. I've been hovering at 175 lbs., and can tell if I get too many carbs because at night I get the whole thermogenenic effect of the body trying to burn off the excess calories instead of storing them.

My ultimate goal is to get strong, get endurance, lean out with a v-taper, and stay there.

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Oh.. forgot to add, been doing it for about three weeks... no noticeable differences other than energy is up, but no weight loss or leaning out. – Jamie G. Jul 24 2011 at 21:28
what makes you think you are leptin-resistant? just curious. – g. Jul 25 2011 at 4:21
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Dr. Kruse says on his blog, "The easiest way to do so if your heavy is to look in the mirror. If your overweight you definitely are leptin resistant. If you still have a large appetite and crave carbohydrates especially at night these are also signs that you likely are LR." Yup, that pretty much describes me. So doing the reset isn't going to hurt anything. – Jamie G. Jul 25 2011 at 11:43
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Correct Jaime...your case is easy then. But skinny folks can be LR too. There are other causes. The thread on MDA is pretty detailed. – The Quilt Jul 25 2011 at 11:46
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I did it for a few weeks but found it too restrictive while I was breastfeeding as I tend to get very snackish after my son's big before sleep feed which is after dinner around nine. (He nurses for almost an hour!!! I'm usually thirsty as hell and starving afterwards.) I also found eating 50+ grams of protein AND nursing first thing in the AM was making me really sluggish in the morning. I almost need that little bit of cortisol to get going.

I'm losing weight without it anyway but I was trying to kick it up a notch, which probably wasn't the best idea while I'm nursing. I did lose weight a little faster (almost 5 pounds the first week and 2 pounds a week the next two weeks) while I was doing the protocol so I think it works, but it just made me too tired. I'll probably try it again after I've weaned my son in a year or two if I have any lingering mommy weight left.

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That last nursing the baby down at night is what keeps getting me too. The days I've realllly made a big ass breakfast, and keep up with the coconut oil every meal, I've been able to make it all the way through to dinner no problem, and pass out after marathon nursing, but it has been difficult to calculate ahead of time my true energy needs. I'm sticking with the big breakfasts as best I can, they do help, but if I need a post baby nursing meal, so be it. We make milk all night for that big morning nursing session, so it makes sense to me why our bodies would demand a night time meal. – Happy Now Sep 15 2011 at 19:10
I'm glad it's not just me. I was really starting to doubt my willpower. – Aughra Sep 15 2011 at 21:10
Do you find the combination of nursing first thing in the AM plus big ass breakfast makes you sleepy? When I follow the big protein breakfast I find myself napping with my son during his 10AM nap. I almost miss that AM cortisol spike! I guess I could grin and bear the laziness for 8 weeks. Haha – Aughra Sep 15 2011 at 21:15
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Been doing the protocol for about 2 weeks, with 50 g breakfast protein and VLC or very close to it. Ended a weight-loss plateau that I'd had for at least a month, but currently on a new, mini-plateau of several days' duration. Very probably due to cortisol; stress level's up this week.

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awesome that you've seen some progress. Sometimes even a little light at the end of the tunnel does wonders for the soul. – ben61820 Jul 25 2011 at 12:12
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I've decided to try the 50gms of protein first thing in the morning thing and to stick with 2 relatively high fat, moderate protein (~50gms), low carb meals through the day. All paleo/primal based (veg, meat, fat like coconut oil, some nuts, primarily skinless almonds, Brazil nuts, and a few raw walnuts here and there, and some pastured cream/sour cream.) I drink a cup of coffee in the morning and stick to water otherwise. If I need a "snack", I'll take BCAA (~10gms).

I've also been using Natural Calm and like how it tastes (I also like how it masks the taste of my ConcenTrace Zinc drops) even though I've read that it isn't the most bioavailable form of magnesium (will try glycinate the next time I shop for supplements).

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Update: After 4 days I feel like my body is responding well with no issues such as fatigue, hunger, etc. I am going to start adding some "safe starch" into my evening meal and see how that affects things. – FED at LiveCaveman.com Sep 15 2011 at 22:15
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I'm not going to try it until Mark does his definitive blog on the subject.

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Father-may-I? I hope you are being facetious. – AdrianaG Oct 19 2011 at 16:56
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I started it, but wasn't able to maintain it long.

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Interesting, why not? – Patrik Jul 24 2011 at 19:59
I don't remember what caused it, but I fell off the wagon. – Sara Jul 24 2011 at 21:50
Same for me. Hot Flashes waking me up @ 3am - too early to eat, so there wasn't anyway to follow the steps in the plan. I can't go to work at 5 in the morning, and only get one lunch break at 11:30ish - so there was no way to space the meals and sleep time to work with a 3am wake up call for breakfast, and getting home from work at 6pm. Once I am able to totally solve the sleep issue, I'll try again. – Tikivana Jul 24 2011 at 22:45
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I only made it 5 days into the program. I had the worst cravings I've had in years and they didn't go away. I was clinically depressed beginning on day 3. I didn't have any of those issues on the primal blueprint (75-100 g of carbs) and I was caught off guard by my negative experience with the LR plan. – Nance Sep 14 2011 at 18:20
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Nance, was it low carb flu maybe? Or did it feel different? Switching gears can be a bitch sometimes. – Happy Now Sep 15 2011 at 19:13
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Work stress way up in last 4 weeks. Carb cravings up too. I've been trying to maintain but found myself eating ice cream and chocolate chips cookies lately at night to comfort myself from a stressful day. The next day I pay with a tummy ache.

I have not been able to utilize willpower although I eat paleo all day until my carb cravings kick in at night while cooking for my family.

At about 140 at 5'4 on semi-muscular frame. Have lost 35 pounds in last 11 months with 7 of them being paleo. From previous I know that my target is probably 125-130 with muscularity. I don't think I look fat when I look in the mirror unless I'm naked. (But that's the whole point right?) I'm going to take the Quilt challenge to combat cravings. This is my plan. Will post results intermittently.

My commute is about an hour and I never eat before I leave home so I don’t wake my family. I’ve decided to eat in the car on the way to work so I can eat within the 30 minutes…this is what I’m going to do the first week below . I’ll probably do some variation the 2nd week (replace with cold chicken for example) so my planning/thinking/cooking on the minimum from week to week.

--9 ounces grass fed patties cooked in coconut oil cold (cooked the night before) with about an ounce of raw cheese as bread. --If I get hungry for lunch I’ll have some sardines. If I’m not hungry I won’t. --At night 5 hours before bed…3 eggs cooked in pastured butter or chicken sausage with raw sauerkraut. I’ll also eat some liver sausage and some non-starchy veggies. 1 square of dark chocolate and chai tea. Will replace night meal with steak/veggies or beef liver/onions the next week.

Other than that I’m going to concentrate on getting sleep in a dark room. If my work load decreases (hopefully) I’ll head to the gym in my office for some weights (won’t be able to do it after 5 o’clock) but I’m putting that 2nd to eating/sleeping. I’ve only recently stopped weight training and slow walks due to work load.

Suggestions/criticisms welcome and thank you.

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my commmute is 45 minutes and i work about 100 hours a week. If I can do it anyone can. It just has to be a priority. When you see what it does to cravings you will make time to do it. My cravings ended long ago and have not been seen for about 7 yrs now. Good Luck and looking forward to seeing how you fare. Paleo + Leptin Rx = success – The Quilt Sep 15 2011 at 18:48
Thanks Dr. Kruse. I will take it your advice to heart. Yahoo! – BaconHealsChic Sep 15 2011 at 19:16
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I eat dinner between 5 and 6pm, then don't eat again until 11am the next day. I eat a bigger lunch than dinner. I drink 1 cup of coffee in the morning with 1 pkt of stevia. If I don't get quite full at dinner, I will have a spoonful or two of coconut oil mixed with baker's chocolate and stevia. That cures any evening snack cravings. I have been eating like this for 6+ months and it works really good and I have all the signs of leptin sensitivity. Maybe this schedule would work for you, too. – akman Sep 15 2011 at 20:07
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I was an emotional eater my whole life. I still have to fight the urge to stuff a box of oreos down my throat when things are going bad, but I haven't done it in almost a year. Once I got my eating under control, I found I really 'owned' it. I used to snack from the time I got home from work until supper, then from after supper until I went to bed. I don't do that anymore, either. It is a really awesome feeling being in control of your hunger and not letting hunger control you. Good luck! – akman Sep 15 2011 at 20:31
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Recipe: 1/2 jar of virgin coconut oil, 1/2 stick of butter, 1 whole bar of unsweetened bakers chocolate, 5 pkts of Stevia in the Raw, small handful of unsweetened coconut flakes. Mix together and microwave until melted. Keep in a jar in the cupboard, will have the consistency of peanut butter. Eat a couple spoons of it for dessert. – akman Sep 15 2011 at 20:34
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I'm still in the training wheels phase. I've implemented parts of it, but am still working on others. Maybe I'm just a slow learner, but I did this with paleo too, and it seems to have worked. I think I need a mental preparation phase for anything before I can make lasting change.

Big breakfast and getting all the way to dinner without eating most days has been the easiest part. There is the occasional impulse for a snack, but that usually passes within a minute, I think it is more out of habit than anything.

I have a ravenous little squirt who nurses constantly especially mornings and evenings, so sometimes I am not able to get breakfast until I have nursed him for an hour. In the evenings I sometimes need a small meal after nursing him down too, otherwise I'm too hungry to fall asleep. Maybe it is a leptin catch-22 and I just have to tough it out if I really want fix things, last meal 5 hours before bedtime may have to wait until weaning, I need my sleep.

Sleep has been hit and miss, but seems to be undergoing a transition with shifting to an earlier wake up time (which is good because I've been locked into a 3 am bedtime and 11:30 am wake-up time forever, any earlier and I would feel jetlagged and sick to my stomach). Luckily, my son's sleep/wake cycle seems to be mirroring mine (or is mine mirroring his?).

I've never been a morning person, but I seem to be functioning without coffee if I need to. I haven't cut it completely yet, but more and more decaf is making it into the mix simply because I'm feeling overstimulated by half-caf.

In just a month, of my half-assed version the overhang of my baby belly that had been sticking around for 2 years, has retreated a few inches, nice to see some daylight on my lower abdomen. I've also been able to button some pants that have refused to button for a long time. Not huge changes, but any change feels like a huge change after feeling stuck for a long time.

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My personal experience with nursing was similar. I HAD to eat right before bed or I was so hungry I would stay awake. I actually struggled to keep weight on while nursing (which came as a real shocker). I could eat two meals during the day, BUT that bedtime snack was essential. Once I stopped nursing that hunger went away. I just listened to my body since I was nursing. – none Sep 15 2011 at 20:11
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I thrive on it. I believe that my only symptom of LR beforehand was being obese (bmi as high as 33 at my tipping point), and I have never been addicted to sugar, only bread, which was possibly a better starting point than some have. In ten weeks of eating the big-ass breakfast strictly within 30mins of wakening, I have dropped thirty lbs; my BMI is now between 28 and 29. I think I became LS after about three weeks, as all hunger disappeared and my skin and sleep improved dramatically but I have continued with the protocol as I find it easy and comforting and the weight loss and heightened feeling of well-being very gratifying.

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