I've noticed a few anecdotes here regarding carb-cravings on a relatively lower-fat paleo diet. Looking around the academic lit, there seems to be at least one viable and rat-confirmed explanation for this (which would also help explain appetite disregulation on the SAD, and the success of Taubes-paleo LC for appetite regulation). Potentially, this could also mean prolonged lack of sexual activity exacerbates carb-cravings.
I'm wondering (1) whether the diet-> oxytocin -> satiety connection has been addressed before by any paleo-types and (2) whether this sounds like a viable explanation or not.
I'm an economics student who was pre-med in undergrad, not a neurophysiologist..
Simplified story: So oxytocin (OT) is the famous love hormone. Has all kinds of nice effects, among them a marked decrease in appetite, i.e. increase in satiety and specifically a significant increase in carb-specific satiety. Oleoylethanolamine (OEA) is a nuclear receptor agonist lipid that, among other things, systemically stimulates oxytocin in the brain-stem and hypothalamus. OEA is itself regulated by diet and dietary fat intake specifically stimulates OEA's production (which occurs in the gut) as well as other related satiety-stimulating agents. Finally, oxytocin synthesis is inhibited by dietary sugar intake.
So dietary fats reduce carb-cravings via oxytocin+ stimulation. Sugar exacerbates them via oxytocin inhibition. To eliminate carb-cravings, eliminate sugar (maybe go VLC, substitue with stevia or something?) and up the dietary fat intake. Make sense?
Not sure how dietary protein might factor into this.
Not familiar with Oxytocin but it sounds viable to me. From what I understand, carbs can also stimulate appetite by causing leptin resistance. I've noticed that personally when I eat a meal that is a very high percentage of protein by calorie I tend to crave other non protein foods, mostly carbs. Haven't searched for a mechanism to explain that. Probably partly due to proteins effect on insulin sensitivity but I feel that there might also be another mechanism in place to keep us away from rabbit starvation.
I think carb cravings are part of the broken insulin release mechanism, weak liver issues and blind brain inflammation. Eat high carbs->insulin release and then some->drives circulating blood sugar into fat cells to below brain glucose happy levels->liver weak and can't do glucogenesis fast enough->brain signals craving for glucose. The brain could signal for fat storage release for fuel but it can't see the refrigerator on my back b/c of the elevated insulin. The oxytocin angle sounds right but I think it is a small player, short acting. Insulin is big player in my broken metabolism. I spread out 60-100 grams of carb over 3 meals and don't over eat protein to keep my insulin response low and steady. No cravings and weight stable.
Is there a fat gram rule of thumb 4 Answers