All the studies they did on rats, with fake food.. done on real humans with real food..!!

Abstract

The paleolithic diet provides health benefits and increases longevity compared to USDA dietary guidelines diet.

Introduction

Human nutrition researchers are increasingly exploring the role evolution has played in the development of modern human physiology and are becoming aware of various nutritionally related disorders in Western societies that are not observed in a number of modern hunter-gatherer populations

Methods

This was a clinically controlled study, where the food intake by the participants was monitored at all times. Two groups of volunteers participated in the study. The "USDA" group was fed the diet recommended by the USDA - 6 portions of grains per day, blah blah. The "Paleo" group was fed according to the principles of the paleo diet - absolutely no food was used that was not available to Homo Sapiens 20,000 years ago or earlier. The study was conducted over the duration of 70 years. All other conditions were strictly the same for both groups.

Results

Only 52% of the "USDA" group completed the study. The remaining 48% have died from the following causes: Chronic heart disease, 22%. Diabetes: 12%. Other causes: 14%. Of the "Paleo" group, 95% completed the study, all of them in good health. The remaining 5% have died from the following causes: quietly in their sleep, 5%

Discussion

The Paleo diet was determined to be 2134% superior to the USDA recommended died (alpha 0.05, beta 0.1).

Conclusion

The New USDA Dietary Guidelines: Total Hogwash

References

This does not count towards my GPA, so I'll skip this section.

I have tonnes of ideas for studies, my dream would be to have my own food company selling traditional foods in order to fund nutrition research.

1. Magnesium in the prevention of gestational diabetes.
2. Glycine in the aftermath of stroke, there's already one small study but I can't find any bigger follow-ups
3. Coconut oil for alzheimer's, all I've seen so far is one case report
4. Vitamin D for autism, I expect I won't be waiting too long for that one.
5. K2 for the treatment of cancer
6. A properly powered study in the treatment of cancer with a clean keto diet. Have you seen the processed crap they are feeding people as part of the ReCHARGE study? Ugh.

I could go on and on, I get about 3 ideas for studies a day, I work in research but unfortunately not qualified to be a PI yet.

What a great question. I want to conduct a study on paleo-raised vs SAD-raised children. It is astounding how many people deal with disorders that seem to be preventable by living thoughtfully and responsibly. The number of people who pop pills for mood/anxiety/learning disorders still shocks me every time I think about it. I work in mental health (Autism mostly), and after reading Primal Body, Primal Mind by Nora Gedgaudus, I am so cued in to this topic. I would hypothesize that significantly fewer cases of developmental disorders, mood disorders and mental disorders (and disease in general OF COURSE) would occur in the paleo group than in the SAD group. I would also like track the lineage data in this study- parents' diets. Since what we put in and on our bodies affects how our genes are expressed, this should yield interesting results too.

This concept is just common sense and simple, but I am interested to get these solid numbers. Something similar may be out there that I haven't found yet.. Of course, my future kid will be my own case study, but I know it will be too hard to remain objective and unbiased. :)

Metabolic ward: Moderate PUFA low fructose, Moderate Fructose low pufa, Moderate PUFA & Fructose, low PUFA & Fructose, Low PUFA & no Fructose. Overall carbohydrate, fat, and protein controlled for.

Definitely Vitamin D and autism.

great question! i am actually about to start my grad degree in nutrition and want to focus my thesis on some aspect of the paleo diet. i am very curious to see how people answer this question!

I know Gary Taubes already hit it up in GCBC but I would love to see a study that definitively researched the link between cholesterol and heart disease. It would be an official N=1 Fat=Good for the entire US. No more explaining how I stay fit on a high fat diet.

I would be interested in the effect of food on alzeimer's, ADHD and autism, hyperactivity in children, depression...anything that has to do with the gut/brain connection.

If I had billions of dollars I would pay for it. As it stands now I can donate about $25. Who else can chip in?

Too long term, but seeing the current state of some of the elderly population, I am wondering if there is a link to Liver/Bone Marrow consumption (or lack thereof) and occurrence of Alzheimer's.

Wellness/holistic health vs. standard medical intervention on a large scale. I have heard it stated that up to 95% of all disease and illness is likely due to lifestyle. Would be interesting to see what percentage it is without question. A study like this not only has funding issues obviously, but this is my imaginary study so :P.

Study focus on morbidity, mortality, and parameters of optimal function and not just the absence of symptoms with our current level of other technologies.

Evgeny hit on it, but basically we need a version of Framingham for dietary options.

Low fat, high carb vs. Paleo vs. SAD

You subsidize the participants, find some highly technical and invasive mechanism to eliminate confounders having to do with reporting and physical activity, and subsidize the grocery tabs such that the per capita expense for each cohort is the same.

End points would be incidence of heart disease, diabetes, stroke, and cancer. Also, at inception each potential participant would be able to select into which cohort he or she would be placed, helping eliminate additional confounders having to do with adherence.

Some of the more technical suggestions would be fascinating, and are far more likely to get funded, but I personally think one of the problems with dietary research is the predilection of scientists to research nutrients rather than food, if you get what I'm saying. People don't eat monounsaturated fat, carbs, and NaCl. They eat olive oil, bread, and canned soup.