I am 33, 5'10 and 240 lbs. I enjoy long walks on the beach... er sorry, wrong website.
So a while back, I came down with some sort of undiagnosed sickness. In the process of not finding the cause of my issue, my GP performed an ultra sound and noticed that I had an enlarged liver. I dont drink very often these days, and even in the prime drinking days of the past, I dont think I drank enough to be for alcohol to be the prime factor. Undiagnosed sickness is gone. Liver is still in there.
GP thinks it may have been non-alcohol fatty liver disease. I have since moved from the US to the UK and dont see the GP for follow up.
Is anyone familiar with Fatty Liver Disease? Effects of paleo on this? Lots of reading points me to cut out meats and fatty meats. I dont want to do this. I have had success with paleo in the past (lost 35 lbs that I have but back on)
My current diet looks like this:
Breakfast: 2 eggs, 3 pieces bacon, avocado, tomatoes & half banana
Lunch: Usually leftover dinner
Dinner: Any combo of lamb, beef, pork, veggies, sweet potatoes, paleo recipes from the web (thanks to my ultra supportive wife). I always use coconut oil for cooking. Butter, salt, pepper, spicy peppers.
Thanks for any guidance!
You can easily give rats a fatty liver by feeding them a combination of corn oil (high in omega-6) and alcohol. You can substitute fructose for the alcohol or even olive oil for the corn oil (so much for olive oil being healthy - at least in large amounts). Replace olive oil or corn oil with saturated fat and voila! No fatty liver. Take home message: The meat is not the problem.
Choline and coconut oil are helpful in getting fat out of the liver. Choline is highest in eggs and beef liver. Read Chris Masterjohn and Peter at Hyperlipid and Dr. Mike Eades.
On the last link, you can read the whole thing or scroll down to the section on "Fatty Liver"
Were you on paleo when you got the diagnoses? Your diet looks pretty good for the most part maybe replace the banana with sweet potato to further lower fructose load as it seems to be implicated in FLD.
Here's some inf that might be helpful to you:
Robert Lustig: That's correct. And then the last thing that fructose does in the liver is it initiates an enzyme called Junk one, and Junk one has been shown by investigators at Harvard Medical School basically is the inflammation pathway and when you initiate Junk one what happens is that your insulin receptor in your liver stops working. It's phosphorylated in a way that basically inactivates it, serum phosphorylation it's called and when your insulin receptor doesn't work in your liver that means your insulin levels all over your body have to rise. And when that happens basically you're going to interfere with normal brain metabolism of the insulin signal which is part of this leptin phenomenon I mentioned before. It's also going to increase the amount of insulin at the adipocyte storing more energy. And you put all of this together and basically you've got a feed forward system of increased insulin, increased liver fat, liver deposition of fat, increased inflammation -- you end up with non-alcoholic fatty liver disease. You end up with your inability to see your leptin and so you consume more fructose and you've now got a viscious cycle out of control.
In fact fructose, because of the way it's metabolised, is actually damaging your liver the same way alcohol is. In fact it's the exact same pathway, in fact fructose is alcohol without the buzz.
Norman Swan: So this is the obesity related fatty liver disease that people talk about?
Robert Lustig: Exactly.
I think this is probably enough for a start. There's lots more out there to read.
Glad you are going paleo!
Stephan's posts (esp the old one's specifically on reversing fatty liver) are pretty comprehensive. Choline and B-vitamins are important aside from reducing PUFA and fructose.
There's no reason to think that fat (unless it's polyunsaturated) and meat cause fatty liver except on the assumption that fat makes you fat and fatty liver is caused by too much fat.
Fasting might also help. This recent study finds a reduction in fatty liver (and fatty pancreas) through extreme but very short calorie restriction. Fasting will help with the overall weight loss that the study says (somewhat dogmatically) is the cause (i.e. the problem is too many calories, the solution is too few) and may prompt your liver to burn its fat stores if you deplete glycogen and don't give it anything else to run on.
About 7 years ago, I was a 5'10 male, 250lbs. I noticed when I would sit for long or lay on my side I would get a pain where my liver was. Figuring it was just cancer and I was going to die anyway, I never told anyone about it as I didn't want to mess around with liver biopsies, chemo all that--just set me on an ice floe and push me to sea is my preferred way to go. Anyway, 2 years later, a routine lab showed ALT (a liver function) was 100 (normal 30-65). They sent me for a liver ultrasound and found I had fatty liver disease. Crap, that meant 60 more years on this planet--better get healthy. Long story short, started eating paleo--fatty liver in perfect health now. Didn't happen until I cut out grains and sugar, a CW diet of high carb, low fat actually made it hurt worse. I still eat the occasional piece of fruit, but no noshing on oreos and doughnuts. ALT was 41 last month. not sure what AST is, but that went from 37 to 21. So--give up sugar and grain and eat real food--you'll get better.
Do you lift weights?
Almost all my friends, heavyweight and lightweight alike in the strongman community, had out-of-whack liver panels, some of which had off-kilter enzymes, all of which had elevated creatinine, and many others (myself included) had fatty liver.
After dropping the intense (3-4 hour sessions in the gym daily) weightlifting regimen my liver panels returned to normal (after about 1 years time).
Have you had your liver enzymes checked? My Mum is going through this at the moment and her enzymes have been elevated for a very long time in particular ALP. Doc is running further tests (ALP iso enzymes to be specific) to determine what is causing this - whether it's linked to bones or something else.
Definitely get a liver function test run with enzymes and go from there.
some herbs you may like to try for a fatty liver: green tea, milk thistle and turmeric, goose grass (cleavers), dandelion and nettle.
Find the first three in the store, the others in the garden - make an infusion from them and drink every morning.
If you can find cleavers, this is especially good:
I also have fatty liver(Nash). About 50% patients come with the symptoms of fatty liver before they get diagnosed as diabetes( type 2) according to the principles of Medicin (((( Harisons).
So the important thing is to control your sugar level. you are not known diabetic but it is a signal.
for the treatment one can use...... green tea, black tea, coffe( decrease insulin resistance) B vitamins, low dose E vit(200 mg or 100 mg) excercis, limon and metformin.
Avoid using all white flour produtcs.