Thinking of this in a similar way that T.S. Wiley implicates electricity and the light bulb...
The automobile's popularity rise seems to chart a similar path as the rise in heart disease, obesity, etc
Driving can be seen as an acute stress, constantly having to make decisions to avoid accidents on even the most routine trips.
An acute stress that happens for a couple of hours every day could then be considered a chronic stress
I have noticed that when I get in the car soon after eating (within 15 mins), I do not digest my food as well. If this is true for others this can also have implications in nutrient deficiencies
If someone does get in an accident, even a minor one, it is highly possible that they will have been shaken up sufficiently to have increased cortisol/inflammatory cytokine production
Very few people in our modern world are able to de-stress, so if that chronic stress (from normal daily driving) or additional stress from an accident builds up it will stay elevated. Then we can see chronically high cortisol/CRP/IL6, etc
Driving has replaced walking for most people even for the shortest trips to the bank, grocery store, and so walking is often only done to and from the car
Has driving been erroneously neglected from the talk of Neolithic Agents of Disease?
Edit: Is there anything to help offset these new issues? Good sleep and meditation probably, but anything else?