Paleo Diet and Paleolithic Diet Questions & Answers

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I would like to know ig the above diet is positively(ie. Promotes)related to longevity or if it has the opposite effect or is unrelated. I would(as mosr would)love to live as well/long as possible. Does the oft-touted metabolic stress associated with this diet have validity?

flag	asked Oct 10 2011 at 6:56 MRDuke 240●1●3

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if you're not overweight and/or carb-addicted, there's no reason for you to go VLC, in my opinion. I personally feel better with lots of starch in my diet and rather moderate fat. Sorry, I don't have a scientific answer. Personally, I felt awful in ketosis after a week or so. And athletic performance and recovery sucked too. So, for me, the answer is no. – annamalia Oct 10 2011 at 7:29

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Check out ncbi.nlm.nih.gov/pmc/articles/PMC2831640 – majkinetor Oct 10 2011 at 12:23

measuring markers that CW thinks will lead to longevity is fail imo. – cliff Oct 10 2011 at 13:20

Ambimorph · Answer 1 · 2011-10-10 19:10:58Z UTC

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I would wager that a ketogenic diet (VLC) is the most longevity promoting diet.

See this question, and my answer to it there.

As to it causing metabolic stress, I don't think that is correct, please see the discussion here.

answered Oct 10 2011 at 19:10

Ambimorph
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To the anonymous downvoter: considering that this answer is explicitly my opinion, and has links to references and well-reasoned arguments (whether or not their conclusions are correct), your action is not very constructive. I mention this not because it matters much in the grand scheme of things, but mainly because I'm getting irked at the recent pattern of getting a downvote for every VLC-positive question answer I write, no matter how thoughtful, or what disclaimers included. Most likely they are all from the same person. – Ambimorph Oct 10 2011 at 19:46

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I'd like to ask that person to consider respecting the opinions of others, agreeing to disagree on certain points, and to save his downvotes for things that are objectively wrong, rude, or irrelevant. – Ambimorph Oct 10 2011 at 19:47

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vlc =good. least amount of digestive trouble no putrefaction that in irself musr count for something positive in the grand scheme. – MRDuke Oct 10 2011 at 21:23

Plus one....... – The Quilt Oct 10 2011 at 21:35

Duke, if you mean VLCers produce less feces pound per pound, I agree. But since when the size of your poop determined your health? Neil Diamond actually pointed out that the larger poop size of the aborigines (due to fiber consumption) denoted better GI health than those eating the SAD. – Namby Pamby Oct 11 2011 at 3:34

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Steve Parker MD · Answer 2 · 2011-10-10 12:12:01Z UTC

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Nobody knows the answer to your question, MRDuke. The studies haven't been done.

Consider, however, Dan Buettner's Blue Zones: none of his longevity hot spots were eating chronic very-low-carb or even low-carb. Buettner considered the hot spot diets to be mostly "plant-based," which isn't to say meat-free.

-Steve

answered Oct 10 2011 at 12:12

Steve Parker MD
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	hence my question: lots of native amercans followed the vlc diet(eg.eskimo)but few lived as long as those not. however if health begins in the gut wouldnt vlc be a better option? if..... – MRDuke Oct 10 2011 at 21:25
	Lots of natives followed the ketogenic diet? Except for the Inuits, it would be hard to find any: maybe the Blackfeet tribe of the plains that lived off of buffalo herds and pemmicans. That's about it, plus the milk tribes of central Africa: the Masais, the Dinkas, etc. That's all. Everyone else ate tubers like there is no tomorrow. – Namby Pamby Oct 11 2011 at 3:30

Namby Pamby · Answer 3 · 2011-10-10 14:57:42Z UTC

Arguably you can relieve metabolic stress by restricting protein consumption. According to Nora, the maximum protein consumption for someone is equal to 80% of your weight in kilogram. So for someone weighing 160 lbs.,

Max(Protein) = 160 / 2.2 = 73 kg x 80% ~ 60g

Not a lot. Combine this with calorie restriction, which has been proven to induce longevity in lab animals. I would combine protein restriction with the Jaminets' PHD, which means about 40% (800 kcal) of your daily kcal needs in carbs + protein. Pick 40%, since 30% (600kcal) is the floor.

You have your protein percentage (60 x 4.1 = 240 kcal) already; so the rest is 560 or 560/3.8 = 150g in carbs. Then, the rest is 1200 in fat or 1200/8.8 = 140g.

So what do we have?

12% protein. 28% carbs. 60% fat. That satisfies BOTH protein restriction and glucose sufficiency (according to PHD), as well as caloric restriction; at 2,000 cals and 160 lbs., you'll lean out, lose some weight, and stay healthy until the day you die.

Beth-WeightMaven · Answer 4 · 2011-10-10 10:55:09Z UTC

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Check out Nora Gedgaudas' presentation at AHS11. I don't follow her prescription for low protein and low carb, but her comments re paleo CRON were interesting. If you're interested in longevity, perhaps there's something there.

answered Oct 10 2011 at 10:55

Beth-WeightMaven
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	Those really are not hers......they are from lots of longevity research but the data is far from clear in primates and humans. Studies arenon going now about this issue in primates and humans. – The Quilt Oct 10 2011 at 15:21
	I didn't say the ideas were hers, but she did talk about them at AHS and I did find the comments interesting ;). – Beth-WeightMaven Oct 10 2011 at 18:11

The Quilt · Answer 5 · 2011-10-10 15:26:35Z UTC

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My personal feelings on both IGF1 and mTOR signaling and longevity are both are bad when he backround cellular terroir is inflammatory by not when hs crp is low......why? Studies on hgh and heart failure in low inflammatory states increases life span and increases their telomere lengths. Moreover studies on high carnosine intakes (more dietary protein) show increased telomere lengths as well as long as hs crp is low.......these studies show that cron and igf1 signaling also must be put into proper context.

answered Oct 10 2011 at 15:26

The Quilt
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	"Studies on hgh and heart failure in low inflammatory states increases life span and increases their telomere lengths" KEY...LOW inflammatory states...good luck finding many people with that – Mallory Oct 10 2011 at 16:37
	Quilt, how would you define low inflammatory state? HS CRP below 0.3? Or is there a better inflammation marker (e.g., IL-6) for that low state? – Namby Pamby Oct 10 2011 at 18:01
	so...maybe recombinant hgh is a good idea aftet all inflammation or no inflammation.... – MRDuke Oct 10 2011 at 21:30
	Namby the best test is spectra telomere test......but i use a clinical battery to assess the backround cellular terroir. I want them all low and then i think eating a diet that stimulates igf1 and mTOR works. Mallory is correct tht this basket of people is small in america.....but it makes up a large percentage of patients in an age management practice because this is how they are taught to eat – The Quilt Oct 10 2011 at 21:39
	Mr Duke, Dr Jeff Life is a friend as are many of the anti aging docs......they convinced me of this about three yrs ago. The key is getting patients to eat this diet. Its easier when it is a paleo approach. Jeff eats a modified mediterrean diet but its quite good minus some grains...low in fructose, and pufas for sure and pretty high in protein and carbs – The Quilt Oct 10 2011 at 21:41

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vlc/lc keto diet and longevity

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