Extract of oregano, coffee, thyme, clove, and walnuts inhibits NF-kappaB in monocytes and in transgenic reporter mice.
Full free text:
First, in vitro:
"A combined extract of clove, oregano, thyme, walnuts, and coffee synergistically inhibited lipopolysaccaride (LPS)-induced NF-κB activation in a monocytic cell line, compared with the sum of effects from the single extracts."
Then, in vivo (mice):
"Based on the area under the curve, the extract decreased whole body LPS-induced NF-κB activity the first 6 hours by 35% compared with control mice."
Is this a good strategy for reducing systemic inflammation?
Or is it just another lame try to get me eating walnuts again?
(Note that one of the authors is a member of the Scientific Advisory Council of the California Walnut Commission)