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---------THIRD PARTY EDIT------------
The below hack is old stuff. It's interesting background from the spring of 2011, but you might want to read these more current posts:
What’s the deal with PaleoHacks, Dr. Kruse and the FBI?
Richard's blog post about Jack's latest events
Jack's blog post on CT12
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BACKGROUND

There was a paleohacks thread yesterday about how much we should trust various sources of information. We’re lucky to have some very smart people posting interesting information on paleohacks, such as Ron Rosedale, Cate Shanahan, and The Quilt.

Lately there have been many posts about people having positive results with The Quilt's Leptin Rx. The science is complex, but it definitely piqued my curiosity. As an information junkie, I decided to scan through what the Internet could tell me about The Quilt and his ideas.

I found some very positive things, but several fairly disturbing things as well. Please excuse this extremely lengthy hack, but I do believe it is of value.

POSITIVES

Let me start by saying that it's clear Jack has some very positive things to contribute to the paleosphere:
- Quilt is a neurosurgeon. Thus, he definitely knows science. Has a strong grasp of several fields, from cell-level to organ-level.
- Quilt gives free advice and will personally answer your questions. Very cool for a busy surgeon.
- Those who follow his protocol appear to be having success.
- The guy can think out of the box. He is curious about all aspects of health. He lost a bunch of weight, and thus walks the walk in addition to talking the talk.
- Quilt can be both serious and funny. See Halloween 2011(NSFW/NSFL) version of Quilt. He is a longstanding and active member of paleohacks who often provides interesting viewpoints.

NEGATIVES

In looking into his writings further though, I found some disturbing trends. Perhaps I am over reacting? Misinterpreting?

Quilt on cancer reduction through nipple massages
Quilt: "nipple massage will reduce your risk of breast CA by 50% because of the sensitivity to oxytocin....."

Quilt on MUFAs Quilt: "Mufa's are more sensitive to oxidation. This is why avocado brown so fast when cut. Unstable."
Matthew: "The browning of avocados has nothing to do with mono-unsaturated fatty acids. It is an enzymatic reaction cross-linking phenolic compounds to protect the damaged fruit against microbes."
Kamal: "'Tis true. The culprit is exposed enzymes, not fatty acid oxidation. You can't just go around making stuff up to prove your points. Well, technically you can."
(Current lipid biochemistry indicates that MuFA are very stable...This fact is widely accepted)

Quilt on Mindfulness
Paleohacks user Kamal calls out Quilt for making up statistics:
Quilt: "Mindfulness has shown 56% reduction in cancer recurrence.Show me one drug that even comes close to that number?
Kamal: "Ummm...no. Most of the trial research was done here in Boston at MGH, UMass, and Beth Israel. Neither meta-analyses nor individual trials show a 56% reduction. During the summer that I interned at the Benson-Henry Institute for Mind-Body Medicine, no one (not even the venerable Dr. Benson) threw around those numbers. I'd ask you to cite your sources, but that does not appear to be your modus operandi."
Kamal: "Yesterday, I saw a claim he made about mindfulness reducing cancer recurrence by 56%. Luckily, I had an internship at the biggest mindfulness research center in the country a few years ago, and knew he was wrong. But who is going to do "due diligence" just to make sure that someone isn't making stuff up?"

Just a few of Quilt's factual errors (overstatements, uninformed speculation, possible plagiarism)

Quilt says, "My principles are based around optimizing life through science not opinion”, though responses often appear to be his opinion rather than substantiated or cited scientific (fact/reasoning).
The following examples (taken from paleohacks) are used to illustrate various errors of fact, faulty reasoning, uninformed speculation and possible plagiarism. Quilt: "Leptin control [sic] fat disposition in body parts. This is why women have curves and men dont. Moreover, people with dosordered leptin function have major body comp and fat deposit issues. See any HIV patient as a great example of the other side of this coin."
akd: "Jesus, lipodystrophy is a side effect from some antiretroviral drugs used to manage HIV infections. not everyone who takes antiretrovirals gets it. its not a function fo the HIV infection, and looking up the cause i dont see the word "leptin" anywhere.

RG73, medical student and paleohacks participant questions a statement made by The Quilt
Quilt: "Cross country running or skiing plus paleo is an oxymoron and might eventually kill you via apoptosis or senescence which ever your programmed for first".......I'll pass"
RG73: "Citation that running shortens telomeres please? Running is going to cause apoptosis? Seriously? That makes zero evolutionary sense. Mitochondria work against our telomeres? Separate genomes. What is the biological mechanism? Werner et al. 2008, Werner et al. 2009, Puterman et al. 2010, LaRocca et al. 2010. I mean I could go on with this all day."

ZZ: "Per what I've read on Whole Health Source and PaNu sites, we want to keep PUFA <= 4%."
Quilt: "This number comes from Mary Enig and truthfully no one knows if it is true."
Jay: "The 4% figure does not come from Mary Enig. It comes from real research done by Lands..."

Quilt possibly making up stuff about gelatin:
Quilt: "All gelatin that is commercially produced is loaded with excitotoxins. So i would never eat it. If you make your own with bone broth that is awesome."
Kamal: "Please explain how home made bone broth (producing gelatin) is different than gelatin made from pig skin and powdered in amino acid profile. Both have glutamine. Most (paleo) people get the regular, unhydrolyzed gelatin."
Jay: "QUILT, this is just mechanistic speculation. Moreover, it doesn't even seem well-founded."
Matthew: "Interesting fact: A breakfast made up beef containing 50 grams of protein can contain 10 grams of glutamate. In contrast 10 grams of gelatin contains only 0.5 grams of glutamate."
One of many instances of Quilt posting something but not acknowledging that the source is another website, not him (mild, perhaps unintentional "borrowing" of ideas)...

Matthew: "By the way, have the LEF been pinching your work? I realise the above quote is from your blog. If you look under the Vitamin K heading at paragraph 37-38 on this page it looks quite similar to the last six lines above..."

Quilt willy-nilly attacks other paleo gurus even when they have never heard of Quilt. See here for Kurt Harris getting pissed off by Quilt...
Dr. Kruse: "While i like both of these guys, neither one has any clinical experience treating cancer patients. They read literature. When kurt was a practicing doc he spent time in a dark room with films not patients."
Kurt Harris MD: "I suppose referring to my by my Christian name when I have never met you supports the impression you know a single thing about my clinical practice or career.You don't. I have had varied and intimate contact with patients doing interventional radiology, including neurointerventional for over 25 years. For 6 years I performed a person consultation with all of my patients at my own private imaging center - that would be about 12,000 in-person patient encounters. This is where I started treating patients with my diet, through this local contact. And I continue to do it locally and in internet consultation, even if you don't know it because I am not as loud about it as some...I am not clear on what being an oncologist has to do with anything, but you are no more of an oncologist than I am. You are a dentist and neurosurgeon. Try sticking to your crackpot theorizing rather than knocking a radiologist and physicist for the "madness" of thinking you might not die if you eat a potato...."

Quilt sometimes predicts that eating things he doesn’t like will kill you, making erroneous blanket statements...
ROB: “hadn't had dairy in close to 10 months and finally binged on close to 400 grams of sour cream daily for three days, and I feel great.”
Quilt: “I say eat it.......It will keep me busy down the road...Dairy equal insulin and eventually insulin leads to death. The great circle of life encapsulated.”
Lee: “But doc...full fat, heavy cream for instance, doesnt spike insulin, does it?”
Ikco: “Dairy isn't dairy. Source and type matter enormously. And scare tactics are just lame.”

So I’m looking for some input. Given the type of information I found above, how should I approach the Quilt’s ideas? Sorry if the post sounded antagonistic, but these are simply the facts that I found using a google search and a paleohacks search. I am genuinely interested in what people’s views are on this. Quilt is providing a potentially useful and absolutely free source of information, but I want to know how much I can trust that information, given what I found above (which presumably is just a small slice of what’s out there).

EDIT & NOTE BY PATRIK: I DON'T THINK IS AN APPROPRIATE TOPIC FOR PALEOHACKS GIVEN ITS EMOTIONAL & SUBJECTIVE NATURE. I WILL LEAVE THIS THREAD UP FOR NOW BUT DO NOT TURN THIS INTO A PILE-ON HATE-FEST AGAINST THE QUILT. PLEASE WATCH YOUR EMOTION & LANGUAGE & DON'T BE MEAN. :)

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Are you sure you're in High School? If so, you're like Dougie Howser smart. Oh wait, you're prolly too young to know who he is. :) – none Nov 1 2011 at 22:53
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Wow. This is why I'm glad I don't follow any particular guru. My body so far has been great about giving me strong feedback, so when something works or doesn't work, I don't have to check what so-and-so said in the book or on the blog. People, keep being contrarian and independent-minded; don't depend on ANYBODY (not even the universally well-liked and popular figureheads) to figure out your own body. Nobody has your best interests at heart like you do, and nobody knows what it's like to be you better than you. – Rose Nov 1 2011 at 23:04
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How to know that you're on PH too much: You witnessed nearly all of these exchanges. Good times. – Travis Culp Nov 1 2011 at 23:33
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I say we test his nipple massage hypothesis ourselves. Ladies, after you. – Stabby Nov 1 2011 at 23:48
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I find this type of hack disingenuous as it is clearly anti-Quilt and yet pretends to be neutral. Don't hide behind the faux "oh hey guys I'm not sure if he's unreliable.." while directly quoting and highlighting in bold all the times Quilt is clearly unreliable. Just call the guy out if you think he's full of crap. Personally, I think he's full of crap. – RJ100 Nov 2 2011 at 15:35
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56 Answers

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18

I'll stick with my original answer to yesterday's thread, namely that I read a wide variety of websites and other publications then ponder the information to develop and focus my own thoughts. I'm not close enough to any of these people to make absolute judgments and I am pretty sure they're all mixtures of correct and accidentally incorrect statements in their work and their beliefs. I do get suspicious of anyone who dismisses counter evidence rather than re-working/thinking his/her previous pronouncements.

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Blanket statements and poor biochemistry aside, I cannot stand his poor grammar and lack of punctuation on this site. Most of the time his answers look like they were written by a 3rd grader.

I'm expecting to be down voted by his all too faithful followers but as you pointed out, I'm not the only person he bothers.

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That was what first bothered me too. I can't even read his blog. – mari Nov 1 2011 at 23:05
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If there is good info in his blog it's terribly difficult to read due to the need for improved formatting and editing. – Katherine Nov 2 2011 at 0:07
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+10 (if possible) for grammar and punctuation. This forum could use more attention to such detail. – Tom R. Nov 2 2011 at 2:22
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I'm getting close with all of these ....plus 1's............ – none Nov 2 2011 at 2:42
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Kurt Harris makes grammatical mistakes, particularly when he writes a very hurried post. But regardless of whether you agree with KGH or not, would many people accuse him of being incoherent? I think not. This is not about grammar. – Aravind Nov 2 2011 at 15:47
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There is a misplaced tone of aggressiveness in a lot of what he said, and the comments about Kurt Harris' practice were definitely out of line and frankly, jerky. In my experience these are not the hallmarks of a very profound mind.

I also have a difficult time with unfounded, blanket, black and white statements.

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I think he writes and hits POST before taking a couple of breaths, stepping back, re-reading, re-thinking and so on. He often doesn't come across as a well thought-out guy. Nevertheless, I support the guy's efforts to help. – Anonymous Chump Nov 1 2011 at 23:13
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See, that's the thing though, actual dialogue and debate are positive helpful things, but attacking people whose point of view is different than yours, who happen to be very credible, experienced people as well and making these big statements that are misleading to people are not helpful IMO. – tartare Nov 1 2011 at 23:19
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I can't call you wrong on that, tartare. And it definitely results in Kruse looking bad. Sorry, Quilt, if you're reading this, but I'm pretty sure what I'm saying is true. At least think about it. – Anonymous Chump Nov 1 2011 at 23:25
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Kruse just went off on Harris for recommending "madness" by saying safe starches are probably okay, then later Kruse said it was KGH's cancer comments that he was calling madness. But Harris had made no comments about cancer. Not one. Then Kruse said basically all oncologists recommend ketogenic diets, then Harris (and Emily Deans) pointed out that he was (again) full of crap. His comprehension of facts seems to be on the same level as his ability to write coherently. – Paleo2.0 Nov 1 2011 at 23:32
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Quilt you were just plain wrong and were cold busted in an open forum, but you come back and here and try to pretend otherwise. Is there any wonder why people don't trust what you say at times? – Paleo2.0 Nov 2 2011 at 23:45
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19

I appreciate what he has to say because he makes me think outside the box and he makes me challenge the status quo, as well as my own thought process. I do not take anything anyone says on this forum as gospel or as applying to everyone in every situation, all the time; so he doesn't bother me in the least. I don't mind his faults, as I happen to have many of my own.

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amen........... – Jeff Nov 1 2011 at 23:22
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But shouldn't the status quo be challenged with facts????? Thinking outside the box is great as long as it doesn't put you smack dab in the middle of a...litter box. – Shari Bambino Nov 1 2011 at 23:30
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Shari-I like that he makes me think and I appreciate his intelligence, and the time he takes to share it. There are sooo many "facts" out there, especially on this board, that completely contradict each other. So I do not fault him for his ideas and possible errors. I take his ideas and then research and think for myself. Just like with anyone else on this board. – Annie Nov 1 2011 at 23:34
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well I think the good results reported and recent explanations of the leptin reset don't leave people in a litter box. – Jeff Nov 1 2011 at 23:34
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Plus 13 Jeff. The SAD and other modern toxins put me in a litter box... AWESOME anaology Shari but I would strongly disagree. Quilt's thoughts and art in translating the biochem is what helps me (and many others sick in the cr*pload) to stay out. – grace Nov 2 2011 at 6:42
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this guy says things that are factually wrong and talks down about legitimate science way too much. his advice might work for you and make you healthier - after all, as far as I know he sticks to the paleo framework to some level of strictness, right? but I would take everything he says with a grain of salt. Working in the field doesnt mean he's always got the science down if he's not going to be conscientious about checking sources and facts before he posts and gives advice. MDs are not superhuman. Also, as someone who invokes his authority as an MD almost constantly, I question the ethics of his posts where he does give medical advice without knowing the patient or often having a basis for making recommendations. He should probably be careful about that.

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thank you, awesome agreement here... – Mallory Nov 2 2011 at 1:02
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I can't really answer, because of the whole moderator thing and my past arguments with Quilt.

But I will say that Quilt is very very knowledgeable, and I appreciate his willingness to post free information in an effort to improve people's health.

One just has to be fully informed when evaluating the advice of anyone on the internet, and this is no exception.

"Believe nothing, no matter where you read it, or who said it, no matter if I have said it, unless it agrees with your own reason and your own common sense.”
— Buddha

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Kamal, how are you always so goddamn gracious? It's a very attribute these days. – sarah-ann Nov 1 2011 at 23:28
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Me and ol' Quilty had a rough past, but he's a funny dude. And the dude livens up paleohacks for sure! – Kamal Nov 1 2011 at 23:34
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Wuss......still a +1 though :-) – Aravind Nov 1 2011 at 23:47
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Boulderdash!!!! – ben61820 Nov 2 2011 at 1:21
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I picked the wrong time to run out of upvotes. – Kamal Nov 2 2011 at 1:40
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you know, ive been around here long enough that i have seen the quilt really dig himself into a few holes. ive never appreciated the tone that he uses with people when they question him. "just look it up," is not an acceptable answer when someone asks you to clarify a statement you make. it just speaks to his character in a way that i dont appreciate. i didnt know about most of this stuff here in the question, though i remember the couple of run ins that im mentioned in. seeing it all together is not totally shocking, i have to say. ive sort of long ago dismissed what he has to say since he is such a poor communicator. im also highly suspicious of anyone who gives medical advice over the interwebs. its just not ethical, and shows a lack of judgement.

i cant speak to his science, since that is not where my strengths lay but again ive seen him caught in enough tight spots that im confident that i can get much better information elsewhere.

besides, i find the relationship advice he offers to be borderline abusive. since that is where my strengths lay, i think ill follow my intuition and get my science elsewhere.

that said, im not a fan of gurus anyway. like rose, i follow my body and listen to my intuition. i never depend on information from just one source so when someone like the quilt makes a claim that i cannot verify elsewhere, its automatically dismissed. after three strikes, i stop listening. this is why i love wolf, harris, and sisson so much though. they are always seeking and striving and growing and citing. its hard work convincing people youre right, as it should be.

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Nice answer akd – Aravind Nov 1 2011 at 23:46
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not to mention that if you do "look it up" or read his citations, you can see he's pulling a whole lot of stuff out of thin air. He seems to be counting on the fact that all the biochemistry terms sound really serious and impressive to the average reader to try and slip half-truths and outright lies past them. – Olivia Nov 2 2011 at 1:57
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Great answer, AKD. Like you, I'm not an expert in the science, but I intuitively don't trust people who become abusive or dismissive when they're questioned. I prefer the approach of the other paleo teachers who are interested in sharing what they know and admit to what they don't yet understand. – Jac Nov 2 2011 at 20:32
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lol you clearly have not been around surgeons. Kruse is prob one of the most helpful people, who spends his time contributing ONLINE (because the internet is a better way to disseminate info than via his mouth). as a med student, 90% of the surgeons i know are flat out overworked assholes. give the guy a break, and take his work for what its worth. he's NOT obligated to answer your questions anyways, you are incorrect that he has to even answer you if you ask q's. – DH Nov 6 2011 at 5:18
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I like the Quilt. He turned me on to K2. When you guys live longer, you'll find out that one good idea, per person, per lifetime is about as good as you can expect from any other human being. Think George W Bush as the counter example. :)

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chris masterjohn... hell... weston a price were talking about k2 a looooonnnnnggggg time ago. – luckybastard Nov 1 2011 at 23:32
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actually, I think George Bush would be the kind of guy, that, were he a doctor, might give medical sight unseen advice over the internet. – tartare Nov 1 2011 at 23:34
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So Quilt = George Bush? O.K. I'm good with that one. – Shari Bambino Nov 1 2011 at 23:35
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When I grow up I intend to surround myself with people who try to keep their bad ideas to themselves and respectfully challenge mine if I go spouting them on the internet as gospel. – lunabelle Nov 1 2011 at 23:40
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K2 is not the quilts idea. – being Nov 1 2011 at 23:47
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Mari,

I do not read this as antagonistic at all. The fact that you have presented both positives and negatives was very thoughtful of you. This is a VERY tough question and even tougher to answer fairly. Since it seems really appropriate, I am going to reference my response to the question from Matthew yesterday -

We could go on and on about how someone earns our trust and becomes a "guru" that we rely upon (e.g. formal training, letters before/after their name, personal life transformation story, etc). Peter at Hyperlipid says "no gurus". However my take is that there are gurus, but it is not a tenured position. It needs to be continually earned (or at least not lost).

Perhaps it will be more efficient "via negativa" to answer this question

  • Has he/she ever blatantly lied or falsified information?
  • Does the person make bold claims absent supporting information? I am not talking about cites for every last claim, but at least controversial ones.
  • Does he/she have a history of being litigious on blogs and forums with dissenting views?
  • Is he/she unwilling to consider alternate points of view?
  • Does he/she imply omniscience rather than acknowledging limitations of his/her knowledge?
  • Does the person engage in ad hominem attacks?
  • Does the person have an incoherent writing style? Genius that no one else can comprehend is not very useful.
  • Is the person emotionally unstable? This might seem odd but it is difficult to trust someone, even versed in science, that arguably needs to be institutionalized, or at least get some intensive therapy
  • Is the person respected by his peers? This is not synonymous with complete agreement on all points

I could go on. This is not the be all / end all list, just an off the cuff response to the question. Also, this is obviously not a black-white assessment - there are many shades of grey. But if a person fails enough of the questions, then one must consider the possibility that this person is doing more harm than good for our community.

Also, I do NOT think the argument "well, a lot of people have gotten healthier following his/her advice" holds water. People have gotten healthier following Ornish and Oz also. Correlation is not causation

I don't think it is a secret that I have not always seen eye to eye with Quilt. But I do agree with the positives you have cited and I have nothing against him as an individual. To the extent that you have merely copied these quotes from previous posts/blogs, I have to assume that the veracity of these items are not questionable. However, I think the "facts" you have a presented definitely are cause for concern, particularly the excerpts of distortions and comments Quilt has made. The information you have presented is particularly troublesome because I know there are many new and impressionable members of PH community that need to be mindful of the advice they are receiving.

Let's face it, Quilt has become a significant member of the Paleo community, and with that comes responsibility on his part, dare I say some level of accountability - not simply as a blogger but as an MD and someone that could influence many in a positive way.

The bottom line to me is that there are a many paths forward. So will he,

  1. Not dismiss this post and take the time to address what you've raised in a thoughtful manner analogous to the effort you have taken? And perhaps use it as opportunity for self improvement and growth?
  2. Tell people to f*ck off because he has a following now and doesn't give two sh|ts what others think because he has achieved his objectives in the blogosphere
  3. Love every minute of it!
  4. None of the above

I eagerly await his response. Thanks for posting this question. I hope some day I grow up to be as mature as you (not likely).

JarJaravind, out...

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Number 4. Profit. – Nutritionator Nov 1 2011 at 23:52
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Shut up you dummy! (kisses) – none Nov 1 2011 at 23:57
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@nutritionator - prophet or profit? – none Nov 1 2011 at 23:57
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plus one....... – Matt Nov 2 2011 at 0:49
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@maj - you are entitled to your opinion...as am I. You also left out the part that he is an MD (not just a blogger) in your assessment. – Aravind Nov 2 2011 at 15:31
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If you want free advice, you get exactly what you pay for.

That being said, I do have a question about the Leptin RX (which seems to not jive with my very limited understanding of biochemistry) specifically: If your aim is to increase the perception of leptin by the arcuate nucleus of the hypothalamus, why would you recommend carbohydrate restriction when it results in a drastic reduction in circulating leptin?

http://www.springerlink.com/index/UVUHPQH4UMUVE6VJ.pdf

Even if this protocol greatly enhanced leptin sensitivity, the individual would be working with a substantial leptin handicap. Since Dr. Kruse is himself VLC as far as I know, there isn't even an implicit recommendation to increase carbs once this protocol does its magic unless Dr. Kruse is implying that he himself is still leptin resistant and is still working on correcting it. If that's the case, then we might question this protocol's efficacy. Looking it over, I don't see why it would be ineffective for weight loss (and certainly the many mini-informercial testimonials we see here are at least partially legitimate), but lots of things result in weight loss without addressing leptin sensitivity.

For what it's worth, I personally suspect that leptin resistance (and thus perhaps obesity itself) is the result of excitotoxic substances like the supraphysiological doses of free glutamic acid from MSG or equivalents and aspartic acid from aspartame etc. that many people today ingest that damage the leptin receptors of the hypothalamus (which isn't protected by the blood-brain barrier). As such, if I were to construct a protocol aimed at restoring leptin sensitivity, it would be built around the absolute avoidance of these compounds in the hope that these receptors could be repaired.

http://journals.lww.com/neuroreport/Abstract/1999/04260/The_arcuate_nucleus_is_pivotal_in_mediating_the.5.aspx

http://www.nature.com/oby/journal/v16/n8/abs/oby2008274a.html

Edit: Quilt is on AttacKruse-Control and calling me out for making up that he's VLC. I knew I had read it somewhere: http://paleohacks.com/questions/47258/what-are-some-of-your-magic-tricks-in-your-paleo-lifestyle-that-youd-like-to-s/47278#47278

I also eat a fairly low carb diet. Most days below fifty grams……most below 25 grams of carbs.

I'd sure as hell call that VLC.

I can't keep track of all of the changes that someone makes to their diet. You know I haven't read everything he's written because I'm not in a padded cell. So, he's decided to synch his carb up to the position of Earth in it's revolution around the Sun. Lovely. I've never heard of a single other soul on this planet doing that, so as you might expect I didn't account for that possibility. This is why I said "as far as I know" (now bolded) above.

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If MSG is the issue, than we'd see higher Leptin resistance in certain ethnic groups like Asians and Mexicans. DA know of any evidence for this? – Bread-Eating Beelzebub Nov 2 2011 at 0:02
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This is all very interesting, Melissa and Travis. But it's not salient to the mega-drama going on in this thread :) – Kamal Nov 2 2011 at 0:25
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That's just like me to try to solve obesity while everyone else is in a conga line. – Travis Culp Nov 2 2011 at 0:33
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Leptin is not just a hormone.....its receptor is more important than the hormone level. People who do not know the complexities of leptin think its all about leptin level......enter travis, woo, mallory etc......go read amgens data and realize why they dropped synthetic leptin.......the answer is not in leptin but the receptor. 600 million dollar bet gone south. – The Quilt Nov 2 2011 at 20:46
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I can't believe he did this in a thread alleging that he does this. What I really can't believe is that I besmirched my own good name by giving him the benefit of the doubt and defending him in that other thread, only to be called a liar for a qualified statement of truth here. You'll not see that again. Let his leptin reset zombie horde defend him. I'm done. – Travis Culp Nov 3 2011 at 4:56
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He's obviously in it because he believes it can make a difference. It takes a certain type of character to do what he does. High output and problem solving can go along with increased error rate. Now it's not for me to tell his error rate, but I'd certainly consider a low error rate important in this area. I think he's much more correct where it counts than most doctors you will meet. Nobody is right 100% of the time and everybody can fall prey to the logical pitfalls of being human.

My only critique is the lack of graphics on his blog, though it's not like any paleo author makes much use of that. The things he writes about would really benefit from relationship maps and such.

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bravo! "He is more correct than most docs". After going to thirteen M.D. bozos over a thirty year period for a mysterious illness .I can tell you I would have given my left arm in exchange for Kruse's 51% correctiness ratio. The thirteen bozos averaged about a mere 3-5 %. I had to cure my illness all by my self.I would have save over twenty five years with the Quilts "Nonsense". No doubt. – shah78 Nov 2 2011 at 0:37
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While he does know more than most docs, not sure I'd go to him. I really wouldn't feel comfortable with him performing brain surgery on me. Just sayin. – mari Nov 2 2011 at 0:43
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She is 16 dude. Sixteen! – none Nov 2 2011 at 0:59
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I'd rather have a neurosurgeon who doesn't make shit up and who can string a logical, coherent sentence together. – mari Nov 2 2011 at 1:28
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That's harsh of you with no way to evaluate his skill and practices as a surgeon. Don't think for one second other surgeons have no faults. – Dean Nov 2 2011 at 1:38
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He is confident. Unfortunately, he is also often wrong. That's a bad combination. I don't trust anything he says.

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I been butting heads with Q since the get to on these boards. Good to see others questioning so much of his erroneous commentary – ben61820 Nov 2 2011 at 1:18
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@ben me too. that kind of surety when it comes to something as complex as science and health sends off alarm bells in my head... – luckybastard Nov 2 2011 at 1:19
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@Ben I agree. When he first started posting I felt like I was in the emperor has no clothes or something. I'm only up to second-year university biochemistry but it's clear that so much of what he says is not factually correct or supported by evidence (even his own citations), it's weird to see him elevated to guru status for basically making things up and being really confident about it. – Olivia Nov 2 2011 at 1:54
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Wrong.....post where the science is wrong chief. Make a list and check it twice because i will be ready. Yall dont like how i do things.....and im cool with it. And i am not changing for the audience here. I do things for audience that others alienate. You all are doing a fine job of that daily. – The Quilt Nov 2 2011 at 22:35
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I take issue with the way that people are responding to the Quilt. I'd like to defend him a bit.

Kruse is the type of thinker who consumes large amounts of information and then synthesizes it into a similarly large system. When he writes he is trying to bring out all of the connections that are buzzing in his head. Kruse's emphasis - as a writer - is usually on seeing everything come together, and not necessarily on providing what most of us would consider a polished, professional statement. Further, he is a very busy person who wants to help others, so the practical compromise he accepts is that his comments will be made in haste, with poor grammar, minor errors, and various moments when his tone could be misconstrued as rude or dismissive.

It is true that Dr K is an opinionated person with an aggressive, idiosyncratic sense of humor that sometimes gets him in trouble with some types of readers. But I think that he considers it an acceptable tradeoff to offend this subset of readers if it allows him to help others achieve their health goals.

So far I've talked mostly about Kruse's style, now I'd like to shift some to his content (the two are interrelated).

To begin, I'll just say that I really value Kruse's contributions to the paleo discussion. He seems to pour through more of the scientific literature than anyone else. His attempt to synthesize this literature is also the most ambitious I've seen. Most of the information he conveys is also backed up by clinical experience, so it's not just crackpot theorizing. Rather, it's informed speculation plus experimentation; and that is pretty much what science is. Kruse's background or journey - from dentistry to neurosurgery to optimal nutrition - also gives him a unique vantage point that, to my knowledge, has no parallel in this community.

Admittedly, Kruse's communication skills are not as strong or polished as they could be. His readers have to dig around his articles, make some connections on their own, read through the comments, etc. He makes readers do more work than any other science-literate blogger of which I'm aware. What I've found, however, is that in time most of it actually does come together. When Kruse makes a claim on his blog, or here on Paleohacks, that seems unwarranted and without basis, eventually the explanation and evidence on which it is based comes to light.

As for the guru issue, I'm not one to follow gurus. I follow ideas, and try to take in the ideas that sound the most original, creative, and comprehensive. On this front, it is hard to argue against what Kruse has to offer.

Say what you want about his style or personality, but you can't say that the Quilt's heart isn't in the right place. He obviously spends a great deal of his time contributing to this site and his blog. Dr K answers almost everybody's questions and comments, and he is always game for a debate. Granted, he is not as interested in providing citations as some of us would like him to be, but it is also true that, intellectually, those are the least interesting sorts of requests. When ideas and concepts are at stake, Dr K has been very dynamic, informative, and original.

I don't mind the mistakes here and there. Most people who - like me - work in academia and research know how important making mistakes is to achieving substantial progress. The big picture matters far more than whether or not a few details were mistaken along the way. This is true broadly, and it is especially true in the context of Paleohacks comments. Most of us are not in a rush to convey information that fits into a larger system that is being unveiled in pieces as it comes together before our eyes. Whether Dr K is on the right track or not, this is what he is doing, and I think that it makes sense for all of us who understand this to make special allowances because of it.

As Kruse likes to point out, he is a big boy, so criticize him all you want. He can take it. But let's not give him the wrong idea. Kruse may be doing something special. So far, I think it is pretty impressive, and I want to encourage him to keep pushing forward, minor details and pleasantries be damned.

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pray tell how being offensive helps someone help others? – tartare Nov 2 2011 at 0:39
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pray tell how being incoherent helps someone help others – luckybastard Nov 2 2011 at 0:43
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im sorry, but i hardly think that the ability to communicate ones ideas and provide evidence for those ideas is a "minor detail"!! in fact, its pretty CENTRAL. – being Nov 2 2011 at 0:46
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when people make controversial claims, there is a burden of proof for that person, particularly when those claims could harm someones health. this seems very straightforward. – being Nov 2 2011 at 1:40
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+1. Quilt is quite obviously a net positive. Haters will hate. – Arlokk Nov 2 2011 at 2:32
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i dont believe in leptin resistance, thus i quit reading the quilt after he made the DANGEROUS assertion that someone with hypothalamic amenorrhea is LR...@$$ backwards my friend. when it comes to eating disorders he would do himself a favor NOT to give advice or talk about them period., i wrote this rant over at MDA yesterday:

that reset BS has nothing to do with leptin... protein, and that much, is gonna cause any and everyone to eat less period. no snacking is just another dieting antic to get you to eat less. coconut oil is BS as well, it works for a couple days, after that its NOS, not gonna work.25 carbs...again its a dieting antic.

what does ANYTHING about the 'reset' have to do with leptin...NOTHING. leptin is an evolutionary female based hormone, meaning it is only really important in the context of a female, and in her reproductive years. any reading on the hormone itself shhhhould lead everyone to that conclusion. males can have low leptin, if youre a dieting male it is expected, duh. lose fat=lose leptin....YOUR NOT becoming resistant to it, you just lose it as you lose fat! your not resistant to leptin when your fat either, you have a ton. i dont understand how people dont understand this...

i can also quote this same leptin genius saying 'insulin equals death'....now again, this is impossible. spiking your insulin means your body is shuttling off nutrients/aminos- PERIOD. if you eat sh*t that is supposed to spike insulin but doesnt have the nutrients to back it up(SAD food) then again, duh, your gonna have continuously high insulin b/c your body is waiting for nutrients that aint coming.

if there is ANY truth to dr kruse's stuff, it's that he has it a$$ backwards. what needs to be 'studied' is the brain's insensitivity to dopamine(i swear if someone says this is b/c of leptin resistance.....lol). leptin alters dopamine, i know. but it is the dopamine deficiency that was first. this causes the weight to climb uncontrollably, the hormones to whack out, the insulin to go haywire, the leptin to f-up, the lazy feeling, adrenal fatigue whatever it is...this same dopamine problem leads also to fat burning problems. same reason certain people given depression meds gain weight...it blocks their dopamine receptors. same reason exsmokers gain weight and heroin addicts sudden get fat. anything that does this leads to the body signaling starvation. low leptin leads to dopamine problems...again, NOTHING about this is related to being resistant to leptin in anyway...

insulin is a body fat signal leptin is a body fat signal

to me, low dopamine should be present, along with low leptin on a ketogenic diet. if the body is functioning correctly, this diet in a roundabout way signals 'starvation' i.e, hibernation. if this didnt happen, how would early man have survived hibernation, the responses NEEDED to happen. so, one on a prolonged VLC diet is going to have downgraded dopamine receptors(but a plus, they should be more sensitive), part of the reason a change in diet leads to weight gain and people inevitably feel they will keep gaining. Dr kruse's MASSIVE LIST of testing and supplements will keep your brain high enough to possibly combat some stuff, but i for one am not shoving 283476510354 lbs of pills in my body, ever. period.

NEITHER leptin or insulin will function correctly with a dopamine problem. this is where stephen DOES have some ground in his 'food reward' stuff, i just think he is presenting it wrong. i dont think obesity is a brain disease like he does. its still not all about the brain, studies show insulin resistant muscles ALSO have insulin resistant brains- this, i am guessing is a factor/result of mitochondrial malfunctioning(which i am still reading about). however, if your brain reads low leptin(deficent) then so will your CNS, your liver, your muscles...you have leptin receptors all over your body(and for females the one's on the ovaries are where we get sh*tted on- amenorrhea etc..)

also, leptin is key to muscle breakdown and growth. if youre someone trying to gain muscle and eating lbs of protein with no result, your low on leptin. it factors into protein synthesis/breakdown and IGF.

dr kruse reminds me of Tabues but instead of insulin it is leptin.

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mallory, i've been reading prozac not potatoes and alot of coverage of seretonin and beta-endorphins as it relates to sugar cravings happen there. – luckybastard Nov 2 2011 at 1:01
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Happy birthday Mallory! – none Nov 2 2011 at 1:06
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and i apologize if i am mad but anyone givind medical advice and dietary advice over the net in something as severe as amenorrhea and anorexia....should lose their medical license – Mallory Nov 2 2011 at 1:18
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I agree Mallory. Particularly a neurosurgeon. Since when does performing back surgery also make you an endocrinologist and gynecologist? – Olivia Nov 2 2011 at 1:52
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Taubes and Kruse in the same sentence? Put a knife through my heart why dontcha? I'd upvote the rest of what you said though. – Shari Bambino Nov 2 2011 at 2:23
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So many points raised, I have noticed one other thing worth bringing up that I see in Quilt as well as other progressive/forward thinking clinicians...

They formulate theories that may well be correct but aren't able to prove them inconclusively. Clinical experience shows them what works and doesn't work, and the community will then scrutinize their reasoning regardless of whether the results show success. Lustig also comes to mind, as well as some people I have firsthand experience with who aren't known on a national level.

This is the difference between researcher and clinician, and when clinicians write things they are highly scrutinized.

and a joke to help summarize this whole issue

"What's the difference between a surgeon and God?"

"God doesn't think he's a surgeon"

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I am a new member of this community and English is not my native language so take my opinion for what its worth. I have not followed any of the mentioned "drama" and do not take any sides.
I am sure Dr.K gets a lot of stuff wrong and his attitude and ego seem to be bigger than most, however, he still is a very valuable, prolific and UNIQUE part of this community. He seems to be a cross between several communities - Paleo, Doctors, Quantified Self. There are other Paleo MDs, so what makes him really unique and valuable is the Quantified aspect of his persona. The Quilt is a true Paleo Quant Doctor. He really looks for context. He seems to have access to a lot of lab tests data ,both personal and patients, which allows him to quantify conditions, improvements as well as observe patterns through many lab results. He does not simply read papers, studies, and journals.
At the end of the day, he is the best and most prolific Paleo medical resource for lab testing. He trials and refines his ideas on his patients and himself through numerous lab tests. Thus, while some of his theories and presentations might have flaws, he still provides a very valuable information and hands on experience for free. I would appreciate him for his strengths and unique perspective, while acknowledging his weaknesses.

EDIT:

I seem to not have expressed myself properly and to have appeared as some Quilt die hard fan boy. I couldn't care less about most of Quilt's not well thought out, badly presented, poorly sourced ideas and hypotheses. I do not follow his protocols. However, I have GREAT respect for this guy because of his quantified approach and clinical experimentation. He has access to vast medical resources and most importantly is ACTIVELY using them to improve his own and the public knowledge and understanding of concepts. I can only hope that one day I might encounter a similar doctor in my personal medical journeys and interactions with medical professionals. If this thread results in less or no output from him, this would be a great loss not only for the Paleo community.

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"At the end of the day, he is the best and most prolific Paleo medical resource..." Hmmmmmm..... you are certainly entitled to your opinion, Quil.... oops, I mean tempomat. – Anonymous Chump Nov 2 2011 at 1:28
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^^He's definitely not quilt. I can understand this. Also................. no ellipses – mari Nov 2 2011 at 1:31
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not Quilty y'all. Very different IP. – Bread-Eating Beelzebub Nov 2 2011 at 1:41
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Plus 10+ tempomat – grace Nov 2 2011 at 6:18
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I'll just add a little bit to Eric's answer by saying that I don't think the re-broadcast of ideas without cites is intentional. I have read things that DrK has written here and there, and they sound alot like what I had written. Did he copy me? Did we draw from the same well? I wrote something about Gary Taubes on the Dr. Oz show, and a few months later Taubes wrote something similar. Did he copy me? Probably not, we're both just clever. My impression of DrK is that he is much more concerned with the overall flow and interconnection with ideas, and less so dotting the i's and crossing the T's, is it 56% reduction, 57% reduction? And there are some very uncreative minions who demand that he behave another way, in a more "respectable" way. They throw out "do you have a cite for that" like street thugs roughing up pedestrians who have the temerity to cross their little street corner without payment. Universities and research centers are full of people who can't seem to move one foot in front of the other without checking pubmed. They just can't stand it when someone comes along, leaping, dancing around, doing it all wrong. We would never move forward on anything without people like this. Now as for me, I didn't wait around for pubmed to tell me it was OK to eat the way DrK recommends. YMMV, and that's ok. If his ideas are total crap, he'll either change them, or eventually be run out of town. Let's hope he doesn't get run out on a technicality. That would be bad for everyone.

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I don't think Dr. K will ever be run out of town. He's got moxie. – Kamal Nov 2 2011 at 1:52
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Wow! Two downvotes in four minutes. I must have fans who seek out my work!!!!!! – The Loon Nov 2 2011 at 1:56
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I've got this amazing oil made from real snakes right here! Rub it on your nipples once and it will cure all that ails you! Don't listen to all those sciency naysayers! They just aren't up to speed with my mad genius yet! – lunabelle Nov 2 2011 at 1:57
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Quilt: "....one nipple massage will reduce your risk of breast CA by 50% because of the sensitivity to oxytocin....." – luckybastard Nov 2 2011 at 2:20
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As far as nipple "message" goes, I breastfed for six years straight and my nipples get plenty of other action, so I think I'm in the clear. – lunabelle Nov 2 2011 at 2:23
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Like others, I appreciate The Quilt for his willingness to post. His cryptic answers are more than annoying, and your citations to intentional misrepresentations definitely bring his credibility into question. As for his ideas, I would suggest n=1 like most other information we read about the Paleo diet. If you think a Quilt suggestion sounds legitimate enough, give it a try and see if it works for you.

As an aside, I think this is the best PH post I have read. Thank you for taking the time.

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To be fair, if this post was not allowed, we also wouldn't be able to post things like "Did you see what Dr. Oz just said" or "Do you trust Ray Peat's advice?". This one is touchier, of course, but the analogy does hold. – Kamal Nov 2 2011 at 14:52
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It will be much more productive to intelligently question and criticize specific Quilt ideas or blog posts in separate threads, instead of attacking all his contributions based on his general persona. This whole thread feels like too much drama towards a very active member of the community. In no way do I defend his ideas or persona, but this whole thread does not seem appropriate to me. Every major Paleo blogger has flaws and faulty ideas or statements. However, they should be treated with some level of respect due to their contributions. – tempomat Nov 2 2011 at 16:42
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Maj, im rather enjoying this between surgeries. We are talking about it in surgery this afternoon. We needed some levity with the devastation we are dealing with today – The Quilt Nov 2 2011 at 18:47
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@maji, again, feel free to disagree. Don't know what it is to "fish cats," and I am certainly no saint. However, I don't make boolshit up and post it on blogs. That's for gosh damn sure. – Tom R. Nov 3 2011 at 2:06
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im new to paleohacks but i have to say, majkinetor is the TRUTH. too much hate towards someone who has contributed a ton. in fact i found PH thru Dr. K's blog. :D – DH Nov 6 2011 at 7:19
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I've been doing Paleo on and off for 5 months and want to input just how amazed I am at the dynamics on this website. I know this isn't an answer but see lots of arguments here and just want to be appreciative of this valuable resource. :)

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A point for any of his followers to keep in mind is that a clinician is not necessarily a trained scientist.

Despite his medical knowledge, his results seem to me to be N=1 at this point, just like the rest of us. He's made amazing personal progress with his health and fitness and that's to be respected. Like many of us, he has a great story about regaining his well-being through paleo.

However, I find it hard to believe that he has had sufficient time to collect the clinical data necessary to support his theories; like many of us, he hasn't been paleo for a long time. A careful clinician will not jump to sweeping conclusions based on a few patients, or just his own results. Blanket statements, erroneous cites, and inchoate postings are not solidifying his position.

Given sufficient and rigorous investigation, some of his ideas could prove to be valid while others go to the dustbin. His leptin prescription does seem to be helping some people based on the testimonials here, and he has a strong passion for all things paleo. He's full of ideas and contributes a lot here, but a clear delineation between fact and speculation when making connections between ideas in the medical and academic literature would be helpful and on the level.

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Very balanced post. Nicely done. – Aravind Nov 2 2011 at 3:35
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Great answer, definitely agreed. – karimoo Nov 2 2011 at 13:16
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WTF does "trained scientist" actually mean? – Patrik Nov 2 2011 at 18:44
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A neurosurgeon sure as hell better be a trained scientist. – citrusfire Nov 3 2011 at 12:50
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A neurosurgeon does surgery and is not necessarily a research scientist. The point I'm trying to make is the methods of the clinician versus the researcher are different. Not every clinician is a capable research scientist, though some doctors do live in both worlds. – Chickenosaurus Rex Nov 3 2011 at 14:10
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Im not sure about the science behind it but I switched from IF to eating 50+ grams of protein within 30 min of waking and do notice that Im much more alert in the morning and have more energy during the day. That said, he comes across like an egomaniac sometimes but I take it with a grain of salt

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Exactly my thoughts. I've seen responses at at PH that are extensively worded trying tto clarify people with distraught health thoughts and extremely complicated questions. he is ONE of the only MDs that I've come across who has said that doesn't matter how many degrees are after your name. SO TRUE. – grace Nov 2 2011 at 6:12
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I'd trust a PaleoHacker like Travis, Meredith, Rogue, Nutritionator, Aravind, Kamal, HappyNow, DRAGONFLY, EVa, Matthew and H*LL even cliff before 99% of physicians... no joke. – grace Nov 2 2011 at 6:14
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Whoa- how is it even possible I was mentioned here? Holy crap. I mean that sincerely. – none Nov 3 2011 at 0:03
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u r smart duh. . – Kamal Nov 3 2011 at 0:27
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Some things to remember about the Quilt (and humans in general) ---

0) I have had my differences with The Quilt -- and have had to suspend him from PaleoHacks. But, generally speaking, his intent is to help people --- he is a net benefit for PaleoHacks.

1) No one is perfect.

2) We're all wrong to some degree.

[See my thoughts on this here: http://us1.campaign-archive2.com/?u=48c5aee421576df1d6f5c8e45&id=7740a2bd8f]

3) The Quilt would benefit from doing better marketing & better writing, and less emotion.

UPDATE: WITH MY EXCHANGE WITH THE QUILT BELOW IN THE COMMENTS, MAYBE I COMMENTED TOO SOON.

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I absolutely love the paleohacks / stackexchange platform! It's so visually simple, but also involving (dare I say addicting?). – Kamal Nov 2 2011 at 18:48
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@Quilt -- FYI you are not a "heavy hitter" -- "heavy hitters" don't have to refer to themselves as such. Same goes for "people persons" etc etc – Patrik Nov 2 2011 at 20:23
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@Quilt --- wow, you are so obstinate & emotionally sensitive it is ridiculous -- FOR THE RECORD: I THINK YOU HAVE SOME INTERESTING & POWERFUL IDEAS that a) you do a painfully poor job of communicating b) demand further investigation. As such I HAVE DEFENDED your presence on PaleoHacks >>>EVEN WHEN I THOUGHT YOU WERE WRONG<<< when everyone was calling for your head. Bottom line: YOU ARE YOUR OWN WORST ENEMY. – Patrik Nov 2 2011 at 20:43
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@TheQuilt -- "There is no higher burden i carry because of who i am." is incorrect. You are a physician with moral & legal responsibilities different from most of us. You also have a polarizing style that affects PaleoHacks. Right now, it is a net benefit -- but if it goes net negative, I will protect the PaleoHacks community as I see fit. – Patrik Nov 2 2011 at 20:45
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BTW I love the fact that in an answer on PaleoHacks, I actually defend The Quilt, and the Quilt bites the hand that defends him. Classic irony (you couldn't script this stuff). Doesn't reflect well on you Quilty. – Patrik Nov 2 2011 at 22:10
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I like the positive sentiments that are expressed here. I agree with those who have said that no one is perfect because in all of Quilt's responses that I've been lucky to read or come across (he is almot as prolific as Travis Culp or Eva) he appears intent on not only helping but in clarifying complicated health topics. The negativity expressed I believe is not warranted.

RE Paul Jaminent, in Quilt's defense, I bet he expressed it incorrectly in that he meant Jimmy Moore reqested a writeup (for a response to Paul Jaminent). Just a guess as Jimmy requested this from many. He's a cowboy fur sure and IMHO a good guy. I'd trust my Dad's health to Dr.K and my Dada is a surgeon!

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We also cant reach a tipping point unless we re sharing ideas on our blogs and in our comments. For me the comments there are often better than the posts because it is here where you see how a clinician tackles a problem...people like carbsane think everything a doc does needs a cite. This is why she is marginalized by many. We mesh science with the art of medicine and if youre not facile with the art of medicine you get a carbsane world where rat data trumps experience – The Quilt Nov 2 2011 at 20:43
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Quilt, I never asked you for anything for my blog. Nor have I asked anyone else who has his own blog. The only people I have ever asked for guest posts are people like Mario Renato Iwakura who leave very insightful comments on my blog, and who I think deserve more visibility for their ideas and their contributions. If you have something to say, you have forums on which to say it, and if I think it's something my readers should wish to read, I can point them to it on my Saturday Around the Web posts. – Paul Jaminet Nov 2 2011 at 22:43
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Paul i posted something on your wall about longevity and you asked me about it and then asked me if i would send it to you. I promise on both of my kids lives. It was under jack kruse on your facebook wall and youmeven commented that you found the ideas interesting. You may not even realize we are friends on facebook and i have followed you since your book was published. But i promise you we spoke about this in comments on faceboook. This was not done on a blog it was done on your wall – The Quilt Nov 2 2011 at 22:47
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And it was before i had a blog..... – The Quilt Nov 2 2011 at 22:48
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Quilt, I apologize, you're right. Here's my apology: paleohacks.com/questions/74180/…. – Paul Jaminet Nov 3 2011 at 3:06
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Dr BG you must have just read Quilt's nice responses!! What are your thoughts on his leptin reset?

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I try to read a lot of the smartypants here and Kruse writes a ton so I don't catch everything unless someone reposts. The leptin reset makes sense from reading Eades, Bryon and others, not that I get it all. The Rx is ridiculously brilliant and insane. And it works. I'm doing it bc I become chunkylicious recently from stress, adrenals (being~ single mom, moving, etc) and the Rx is good for adrenals. As suggested I do 25g carbs or more in the AM. Lost 1kg already in 1 wk but I also like to work out. Depending on how poopy the adrenals are, no exercise is probably best. – grace Nov 2 2011 at 7:20
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My husband thinks we do too much meat but this is the beauty why it works very effectively. 50 g is like 7 eggs, 2 big ch breasts, or a chunk of lamb, beef, or pork. I do organic rice, fruit, potatoes, or chocolate for the carbs which help augment the insulin without causing me to chase crwvings and high insulin all day... good luck and I hope to hear more about ur story later! – grace Nov 2 2011 at 7:24
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(Although the question and most of the answers/comments are very respectable and polite, I hope this internet conversation and critique doesn't suffer from the lack of personal contact and non-verbal communication! This would be a much more interesting and fun thread if it was happening with all of us, including Dr. K, around a big fire, eating some meat on a stick, on a cool starlit night in august...)

Only a very subjective comment, and intellectually not very substantual:

Dr. K made paleo difficult! (edit: for me)

All the testing and supplements.

Again, he could be totally right, but paleo used to be easy.

By the way, we still use the easy paleo approach at home...

Cheers,

Pieter

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i think you put your finger on what made me skeptical, pieter. all of a sudden, me taking a very conservative, common sense approach to health wasn't enough. i needed resveratrol? pshaw. i like my version better. – luckybastard Nov 2 2011 at 11:19
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Many people are impelled to challenge conventional wisdom, but forget that paleos were merely humans trying to survive. I blundered in with a belief in the value of hunt-and-gather and meat eating as the most defensible core paleo values. I'm still bewildered by the amount of esoterica posted up here. Leptin theories among many others – thhq Nov 2 2011 at 12:12
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@majkinetor: You're oversimplifying. Do you honestly think people here are stupid and lazy? Most of us have worked quite hard to understand what it is that we're doing. – Chickenosaurus Rex Nov 2 2011 at 15:13
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@majkinetor: To make sure you understand me correct: with simple I mean simple principles to use, not that the science, biochemics, physiology, ... is easy or simple. I like simple like Mark Sisson, Robb Wolf, Kurt Harris, ... Again, I could be wrong, but it seems like the above have good results. – Pieter D Nov 2 2011 at 15:52
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"Dr. K made paleo difficult!" Well, hasn't he been pretty clear that his field is measurably optimal health, longevity, anti-aging etc? Of which he sees paleo as we know it as key but not the only component. I definitely appreciate heavy emphasis on smart testing and situation-contexted supps, and knowing the why's, in order to get a better compass and handle on what's going on with our health beyond the most obvious outward signs or vaguely feeling better. – JoeBranca at paleoplusone.com Nov 2 2011 at 17:42
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The Quilt is a funny guy. My opinion is that you shouldn't let personality get in the way of a) listening to other perspectives and b) when in doubt looking into things for yourself.

Don' t let your personal religion stop you from exploring other's religions and don't hold others accountable for your own personal choices. Make your own choices and decide for yourself what is reliable and not reliable.

There have been many cases in history were a group of people have come together to persecute an idea and in the end the majority was wrong. Don't forget that. Also don't forget that there have been many cases in history where individuals were wrong.

http://paleohacks.com/questions/48074/most-original-influential-helpful-major-person-group-in-the-paleo-primal-health-c#axzz1cY0jhniK

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Nice. So all the nice things are personality and all the crappy things including the judgment to write things whether they are fact or fiction aren't a consequence of personality. BTW... people don't do research and share it with the community unless they are looking for self-confirmation in their own judgement or need persuasion for or against. There is motive either way even if it is just out of curiosity or FYI, that is a personality trait as well. Don't you forget that. LOL. That's my new motto now: "Don't you forget that." – Edward J. Edmonds Nov 2 2011 at 17:09
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The super-annoying spelling/grammar issues aside, my problems with Kruse are:

(1) Science w/o Substantiation:

When someone says "My principles are based around optimizing life through science not opinion”, then they better be prepared to put up or shut up! Quilt is responsible (for better or worse depending on the Hacker - grin) for my return to PH because I asked him on his blog to substantiate a claim that Mg deficiency ALWAYS precedes IR. That is a pretty bold statement. A statement like that implies that there is overwhelming evidence in the peer review literature to support it. A consensus if you will. When I asked him, he first sent me to {paraphrase} 'any biochem text ever published'. Huh? If this is really common knowledge at the textbook level, he should at least have a page number to cite, no? I've searched my PDF copy of G&H Textbook of Medical Physiology and found nothing. Next he sent me to a thread here where others listed a bunch of citations. Lots of info out there linking Mg and IR, but none of the cites I had time to look into further supported the claim.

Bottom line: Kruse's broad authoritative statements lack substantiation most of the time. Instead of providing the information, he would rather send his readers off on wild goose chases. Paleo as those may be, that is not courteous behavior. If your claims are backed by science you've read, referencing the relevant citations should be part of the initial presentation of said claims. Absent that, one should at least be prepared to provide the support when asked.

(2) Consistency:

Jack and I got off to a bad start on my blog. Yeah, I'm not the most politically correct tactful blogger out there, but I call them as I see them. Jack rhymes with the noise a duck makes, and having read about nipple massages and such this guy came off immediately as one to me. Still, at the time many were doing his plan and discussing him over at Jimmy's LLVLC forum. I called him the LLVLC "flavor of the month". Jack took exception to that in my comments saying that he was not low carb and folks at AHS were even shocked by his carb consumption. OK. But then I listened to his interview with Jimmy and read some comments on his blog and ... darnit ... he's supporting Taubes and telling his readers that VLC is what works for him. I asked again in his comments.(#) I got a rude reply. I don't care if he's LC, HC, no C, hyper C. I don't care if he cycles weekly or seasonally, but be consistent! (#Note: I tried to discuss this with him as CarbSane but I was apparently banned from comments and my posts disappeared. So I tested another ID/email and those went to moderation. He let through one comment by me posting as LCC and responded. I tried to respond as CarbSane ... that's in perpetual moderation apparently).

(3) Made Up Words

I initially thought that levee was a typo and he was instead talking about levels. But I was wrong. It's unnecessarily confusing.

(4) WTF Equations????

His Leptin Reset post ends with this:

(QUILT SURVIVABILITY) = (Total Energy – Growth and immunity expense) X (RESOURCES) X (efficiency) X (awareness of our environment)

Stated in levee form where: Cell longevity = LS – IGF-1 + immunity X Food Quality X leakiness of Mitochondria X environmental cues

  1. I have no freakin' clue what to make of such equations!
  2. Is IGF-1 the bad guy?

Point 2 is a biggie b/c PROTEIN stimulates IGF-1. Last I checked his whole plan begins with frontloading a BAHPB. I've asked him about IGF-1 and what stimulates it. He emailed me a paper. If we're talking insulin resistance, IGF-1 is an insulin sensitizer. The work of Gannon & Nuttal in this regard, that I blogged on in The LoBAG Diets for treatment of Type II Diabetes and IGF-I, discusses this.

(5) The "Out"

All anomalies can be explained by whether or not you're leptin sensitive or resistant. If his plan doesn't work, you were obviously already LS. If you have any problem in life, you're definitely LR. Melissa's 100 yr carb eating granny? Must be LS. John Q Pudgy? He's LR. Anyone can make up any old sort of crap when you can simply dismiss what doesn't fit the model with such flippant generalizations.

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+1 for the WTF Equations. Several of us have had a laugh or two about that Evelyn – Aravind Nov 2 2011 at 13:33
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Oh man, I am relieved to learn that even you are perplexed by that equation. I thought it was just me! That I was too dumb to understand it fully. I feel much better about my brain now. Thank you. – none Nov 2 2011 at 13:36
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If she said one nice thing i would have disaapointed. I am now relieved. – The Quilt Nov 2 2011 at 20:27
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Now it's Jack's fault that the supplements that he recommends are expensive??? He is dealing with people with broken metabolisms, or people who want to optimize their bodies. These are people who in all probability will never reach 100% due to the ravages of years of CW. He is pretty clear that most LR people can get fixed without the testing and the supplements; it will just take them a lot longer to get there. Everybody has to their own personal cost-benefit analysis. – AdrianaG Nov 3 2011 at 13:41
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No Adriana, that's not what I said. Getting back to Quilt being about science and not opinion, if he's going to recommend these supps, he needs to back that up with some proof that they actually work in attainable doses. When someone gives you a list of supplements -- let's just say even five -- you try them at what doses? All at once? Etc. Here is where Paul Jaminet shines b/c he WILL cite studies to support recommendations, and if you have an issue I've seen none more generous with his time to share his knowledge than Paul. – Evelyn aka CarbSane Nov 3 2011 at 17:10
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I can't even read all this crap.

Some people seriously have to work on their understanding of life, universe and everything else. The fact that most points got the Nutritionist who talks about the "grammar issues" puts this entire thread on the pre-kindergarten level.

Who cares anyway, Quilt is not here to kill you or torture you or play Megamind but to share his insights and probably to learn about new things himself. Does he makes mistakes and use unchecked information ? Sure, who doesn't. Does he self promote ? Sure, who doesn't. I can compile this kind of BS for any single blogger out there.

The good thing about the internet is that everything is accessible. You don't trust the dude ? Go check it out, if you know how to search.

World would be a much better place if everybody was talking truth and nothing but the truth, right ? Meh...

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+1 "Some people seriously have to work on their understanding of life, universe and everything else." I think we were separated at birth :) – Edward J. Edmonds Nov 2 2011 at 13:26
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the problem is that this paleo thing or whatever you call it is so young that we must police ourselves of those that would discredit the movement. being a purveyor of unchecked info with a hard-on for self-promotion is a dangerous combinations, no? many people come to paleo as a last resort after they feel- many times rightly so- that mainstream medicine and nutrition has failed them. the last person i want them to run into is this guy. mark sisson, robb wolf, kgh, chris kresser? i'm all ok for a person just getting into this to read any of those people. just not this guy. please not this guy. – luckybastard Nov 2 2011 at 13:38
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haha, the first things cults do, cut off loose ends. – Edward J. Edmonds Nov 2 2011 at 13:52
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Your grammar sux bustard. Please stop posting here until you learn how to write. We don't want to discredit this fine community. – majkinetor Nov 2 2011 at 13:53
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That would be some Kaiser Soze shit there! – Kamal Nov 2 2011 at 14:49
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The problem is that Dr. Kruse is a doctor, but he posts a lot of comments and stuff that are less than rigorous. I think when you have that credential burden, you have to be careful what you say. I recommended his blog to my roommates in NYC who were having a lot of trouble with paleo and I think they really benefitted from his Leptin RX, particularly the high protein breakfast. I guess my beef with him is he is so focused on a certain type of sick person that he, like many other low-carb doctors, thinks his prescriptions (like keto) are optimal for everyone and his view of human evolution is shaped by this. There is the second type of sick person, of which there are many on PH, which is the tend to be-underweight malnourished often kind of high-strung sort. That's what I am, and that's what a lot of other people I know are. Keto can help some of these people, but it can make others worse.

Edit: Quilt seems to think I have it in for him. Why would I recommend the Leptin RX to certain people (people I CARE about) then?? I think the Leptin RX can help a lot of people. It is mainly his random comments on the internet I have argued about, particularly on the safe starch debate and on evolutionary biology.

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but he posts a lot of comments and stuff that are less than rigorous* - Thats because he doesn't come here to work Melissa. Funny how that escapes you. – majkinetor Nov 2 2011 at 15:09
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Point one....your perception of what i am is yours. Not mine. Im no low carb doctor. I use a large armentarium to get to optimal. Medicine is not rigorous. If it was no one would be on a statin or taking a bunch of meds that work 50% of the time. Medicine is an art and science in harmony. Your boyfriend signed up for rigorous as a phd candidate. I can alter people with my mind and my clinical skills. You and many others here fall prey to thinking research papers are a lot better resources than clinical expertise. On this we completely disagree. – The Quilt Nov 2 2011 at 23:00
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Your comments on the safe starch debate suggest otherwise. – Bread-Eating Beelzebub Nov 2 2011 at 23:24
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they were very disappointing since before the Rosedale debacle it seemed you were being more reasonable about macros. – Bread-Eating Beelzebub Nov 2 2011 at 23:26
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I am NOT against the Leptin Rx. I have recommended it to many people. It is your random comments on the internet that often are very questionable, not your holistic philosophy. – Bread-Eating Beelzebub Nov 3 2011 at 0:54
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And, yet again, the noise here at PH is rather louder than the signal. Reading Jack is, at the very least, good for generating an idea or two, which turns out to be the point. We need ideas we can test (hopefully with relative safety).

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