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http://www.ncbi.nlm.nih.gov/pubmed/19112401

Can anyone see what the "leaky gut diet" was that worked after 10-14 months along with NAC, glutamine, and Zinc supplementation. This seems like a relatively low key approach to what many seem to do for it.

Anyone got access to the full study?

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That is the least accessible paper I have ever seen. – Matt Nov 10 2011 at 0:31
First of all, it is highly unlikely that someone has full blown 'leaky gut syndrome'. Second, in order to make it better, consume 8-10 grams of L Glutamine a day for 10 days. Should be good to go after that. – Bill1102inf Nov 10 2011 at 5:00

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Google Scholar to the rescue: paper is here. But the full paper isn't that helpful. The diet is described as a "a milk allergic, gluten-free and low-carb diet" (top of p 103).

Emily Deans has a discussion of the case study that preceded this paper on her blog.

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I knew I had read the full text somewhere before :) – Matt Nov 10 2011 at 0:54
Not very informative though. – Matt Nov 10 2011 at 0:58
Yeah. On her blog, Emily says she emailed the author to get more info about the diet but the email to the address provided bounced. – Beth-WeightMaven Nov 10 2011 at 1:02
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I have great success following the suggestions and supplements in "Restoring Your Digestive health" by J S Rubin, NMD and J Brasco, MD. Very Paleo and very simple and very quick. Published 2003 and easy to find used on Amazon.

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In integrative medicine there are the 4 R's (there's actually 7 now! but let's stick to old time basics):

Treating the overall gut, with exclusion or rotation diets, glutamine, fish oils for inflammation, and the entire 4-R program includes:

Treatment Using Four “R” Program for Intestinal Health:

• Remove offending foods, medications, gluten (if sensitive) and reduce high fat foods, refined carbohydrates, sugars, and fermented foods (if yeast is present). Consider antimicrobial, antifungal, and/ or antiparasitic therapies in the case of opportunistic/ pathogenic bacterial, yeast, and/or parasite overgrowth (see otherrecommendations below).

• Replace what is needed for normal digestion and absorption such as betaine HCl, pancreatic enzymes, herbs that aid in digestion such as deglycyrrhizinated licorice and marshmallow root, dietary fiber, and water.

• Reinoculate with favorable microbes (probiotics such as Lactobacillus sp., Bifidobacter sp., and Saccharomyces boulardii). To enhance the growth of the favorable bacteria, supplement with prebiotics such as insulin, xylooligosaccharides, and fiber.

• Repair mucosal lining by giving support to healthy intestinal mucosal cells, goblet cells, and to the immune system. Consider L-glutamine, essential fatty acids, zinc, pantothenic acid and vitamin C.

Other Recommendations for Increasing sIgA

• Exercise and relaxation techniques (such as footbaths, aromatherapy and massage) have been shown to increase sIgA levels.

• Decrease cortisol levels. Cortisol can direct the production of immune cells immuncytes, which produce sIgA.Probiotics (bifidobacter and Lactobacillus bacteria) have been shown to increase sIgA (as well as beneficial short chain fatty acids). They may also activate macrophages.

• Saccharomyces boulardii is used for the prevention and treatment of diarrhea of different etiologies and has been shown to enhance IgA immune response

http://www.metametrix.com/files/learning-center/articles/Secretory-IgA.pdf

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Just to be clear, did you mean "inulin" instead of "insulin" for prebiotics? – Happy Now Nov 10 2011 at 6:17
Sharp eyes -- sorry it should be 'inulin' on the original source. Some people have worse symptoms (bloating) with probiotics and inulin/FOS/fiber/veggies. Their SIBO is severe and they need to calm things down before being able to add these to the program. – grace Nov 11 2011 at 8:38
Is the information helpful? Do you find it adding to your knowledge? Thanks for eyes! – grace Nov 11 2011 at 8:39

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