The information you are looking for is in the article linked below. I was going to try and summarize it for you, but I think you and your friend would be better off reading it. Hope this helps:

http://perfecthealthdiet.com/?p=4457

EDIT: I realize that not everyone will actually click on a link and read it. So, if your friend wants to approach this with a self-experimental approach, he or she can try these potential solutions:

• more carbs (for glucose deficiency)
• iodine (to resolve hypothyroidism)
• selenium (ditto)
• T3 thyroid hormone (ditto) (warning: must titrate off of slowly)
• copper (deficiency linked to lipid metabolism)

Lastly, for more related details from my favorite paleo writer:

http://jackkruse.com/hormone-cascade-101/

Part of it is that her LDL is being calculated based on a triglyceride range that she is not in. Tell her to cut out all butter/cream and re-test in a few months. 5 weeks of doing so about a year ago caused my LDL to decrease by 20-something%. That was going from a fairly high intake though. It's easy to make butter disappear into your vegetables, so she could be eating more than she realizes. I suspect that higher quality butter is more potent in raising LDL than conventional butter, but either way it has a potent effect: http://paleohacks.com/questions/36855/i-think-i-may-have-figured-out-why-some-of-us-have-really-high-ldl#axzz1dt47Bev5

How is her fasting glucose levels? This study shows how important insulin sensitivity in modulating cholesterol levels

http://www.ncbi.nlm.nih.gov/pubmed/20436182