I noticed that several people have talked about megadosing their vitamin C, and I was wondering why? I know the loss of the ability to synthesize vitamin C has been put forward as a reason to megadose, but I'm not sure I understand that as a reason to consume more.
Here is my current knowledge of Vitamin C, based on conventional nutrition:
-Your ability to absorb vitamin C decreases as the dose increases. Ex. 1 g, you absorb 75%; 3 g, you absorb 40%; 5 g, you absorb 25%.
-Vitamin C at very high doses interacts with iron, creating oxidative stress
-A possible "rebound" deficiency occurs when supplementation is stopped because of decreased absorption
The reduced absorption I assume is the reason why people say that taking lots of vitamin C makes for pricey urine.
Has anyone experience health improvement from taking loads of vitamin C? Does anyone have any studies or articles they can direct me towards? I haven't really looked into this, but I thought one of you probably has and could give me a hand!
Anything in excess is generally negative, and can have adverse effects. You will not get any more of the vitamin C benefits (immunity boosting, antioxidant, etc) by overdosing.
Because Vitamin C is water - soluble rather than fat-soluble, and gets excreted in urine, excess levels cannot accumulate in the body the way fat-soluble vitamins like vitamin A can (and hence cause vitamin A toxicity). However, since it is excreted in urine, very high and constant overdoses can put severe stress on the kidneys, and the digestive system (especially diarrhea as the body tries to flush out the excess vitamin C). Remember, in general, the body will flush out the excess if it can, and harm will be caused if it can't, so taking excess levels of vitamins will not give you extra conventional benefit.
There is something, though, that high doses of Vitamin C can be useful for, though I'm not going to recommend it. Vitamin C in high doses is an emmenagogue (it stimulates menstrual flow) and, hence, an abortifacient. Some women have used high vitamin C doses to either stimulate late periods (so it could be a potential amenorrhea solution) or terminate early pregnancies.
Hope this is helpful :-)
Lots of Paleo love
There's a reason why Homo Sapiens is a double knockout for vitamin C and uricase:
Complete loss of a gene indicates that it confers a strong survival advantage. Loss of uricase leads to increased uric acid and higher blood pressure. Higher blood pressure may be necessary if you want to avoid passing out when you stand up and walk around (H. Erectus).
If you avoid supranormal amounts of fructose that have no vitamin C (like Big Gulps), there is no reason to think we need to supplement. In fact, evolution decided against it. Fruit comes with vitamin C (as do many vegetables) - and that should be plenty.
Research megadose Vitamin C before you make these claims that it does nothing but harm. There has NEVER been harm proven from taking high doses of Vitamin C (10-20g). Just do the research and see for yourself. I have been taking the high amounts of it for 2 weeks now and have never felt better.
I starting taking a megadose of Vitamin C for heavy metal detox. What I noticed pretty quick was that I did not need to use my albuteral rescue inhaler any more. I went from using it one to three times a night,to maybe once a week, if that. This is an incredible change in my asthma symptoms. I am taking between 7500mg to 15000mg a day. Just under bowel tolerance.
A couple years ago i was getting sick constantly, even several dreaded "summer colds". I have a toddler who was in daycare and used to bring home all kinds of germs. plus I am a smoker. I finally got frustrated and decided to give the vitamin C a try. I take around 3000mg per day, 5000mg when I would feel some symptoms coming on. it has been over 2 years and I have not gotten the flu once. and this includes a very sick daughter sleeping on my chest and breathing all those little germs right in my face. I finally convinced my wife to try it as well and we both made it through the worst flu season in memory without even a sniffle. the latest little bonus benefit was when one of my wife's friends commented on how amazing my skin looks (I'm 39, she's 25). I try to ignore most "scientific studies", I've always believed my own personal experience will always be 1000x better than what song so called experts claims. I also take around 2000 IU of vitamin D, extra calcium supplements, and around 10,000 RDA of vitamin B. I drink about a gallon & half of water per day so my body is always flushing.