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That's the assertion of this article's title:

http://www.dailymail.co.uk/health/article-2089099/Breast-cancer-cure-linked-cholesterol-lowering-tablets.html

Are there potential confounders at play here?

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Actual journal article: sciencedirect.com/… – Matt Jan 23 2012 at 14:10
Sweet, thanks for linking that. – familygrokumentarian Jan 23 2012 at 15:57

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The fact that these are drugs that are used in hypercholesterolemia is beside the point. They happen to target the mutant p53. It's simply targeting a biosynthetic pathway, shutting it down to prevent cancer growth. Seems like a valid strategy for some cancers, when susceptible.

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Great question. Mind if I revise it slightly?

"What are the potential confounders at play here?

There are always potential confounders. Surely there are some here.

Looking forward to hearing the views of those who have knowledge and/or experience.

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Statins reduce inflammation, that's what gives their positive effects, not reducing cholesterol. The reduced inflammation will help with cancer too, but there are many other ways to reduce inflammation without messing with cholesterol.

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