Does anyone know what the molecular mechanism is behind bovine-derived phosphatidylserine's cortisol blunting effects in response to exercise?
Well thought out detailed theories are welcome too!
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Phosphatidylserine is believed to help re-sensitize the hypothalmic-pituitary-adrenal axis to cortisol, thus reducing its overproduction: There have been limited studies, funded by supplement manufacturers, showing that soy derived PS limits exercise induced stress, however results of the studies are controversial: http://www.med.nyu.edu/content?ChunkIID=21843 Elsewhere on this site (think its the Adaptogens thread) I posted some links to the newly emerging fish derived phosphatidylserine supplements, along with the DHA and/or EPA conjugated forms of soy derived PS. These appear to have chemical strcutures that more closely approximate bovine derived PS. http://paleohacks.com/questions/12136/has-anyone-tried-adaptogens#axzz1ku395h27 |
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Have you read this: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997116/?tool=pmcentrez |
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