Blog

4

Our favorite Dr. Quilt had an interesting post on his blog today, and included some radical ideas on the causes and role of diabetes. He is hinting at the idea that it is not a disease. What do you think about this? http://jackkruse.com/cold-thermogenesis-two/

flag
10 
Is there no end to the nonsense? :) – Matt Feb 23 2012 at 10:26
2 
Anybody can be an expert and have references to back up whatever wild-ass theory they come up with. Thanks, Pubmed! – Matt Feb 23 2012 at 14:31
4 
First article I've read from Kruse... Even if his hypothesis was not completely ridiculous, this man could not compose a sentence to save his life. I only made it about a quarter of the way through before giving up. – Mazer Feb 23 2012 at 15:45

1 Answer

16

It would be helpful to write out the argument, since it is very hard to follow in the first place and has questionable assumptions right out of the gate. There is absolutely no evidence that hibernation is an ancestral characteristic in the hominid line. Or that pre-hominids in our line (Plesiadapis for example) were adapted to cold weather. You pretty much have to have no education whatsoever on primate evolution to even accept his starting points. The only known primate that hibernates does so at tropical temperatures.

And if his theory panned out, diabetes would be more common in polar cultures, particularly those in which neolithic diets have been introduced. But if you look at the data on Siberians (Leonard et al.) that is not the case at all.

And the vast amount of evidence shows that cold weather adaptations are derived, IE pretty recently evolved, and not ancestral to the homo sapiens species. That's why they are so poorly distributed. In fact, they might even be relics of interbreeding with sub-species like Denisovans and Neanderthals.

And if diabetes were an evolutionary relic, why is there so much evidence that it has to do with autoimmunity?

link|flag
1 
difficult because you have no understanding of it........but you will soon and you will then have to rethink your beliefs. What you have done to me is precisely what you accuse modern medicine of doing to modern patients......Im not mad about it because you really not aware of it......YET. We'll see who turns out right. I already the answer. Your in inning one of massive learning project. – The Quilt Feb 23 2012 at 19:40
3 
But Quilt, many of the basic facts upon which you are building your grand theory are simply incorrect or misinterpreted, and they remain so whichever reality you claim to be in. – Matt Feb 23 2012 at 20:19
3 
Um, you failed to refute any of my arguments. You are basically impossible to argue with because you start getting all emo and saying how we just don't see things the way you do. – Bread-Eating Beelzebub Feb 23 2012 at 20:21
What said this chap straight? Was even English? Possibly isn't English its first language? If not, then is which? Possibly it' s the secret? ...... or Babel Fish? – none Feb 24 2012 at 0:53
"I have a lot of diabetics in my practice becoming un diabetic while the rest of the world believes it is a disease……its not a disease. it is a metabolic derangement that the cold fixes. Anyone can rid them selves of this disease if they cold adapt at home." The Quilt wrote this. I'm skeptical. – Anonymous Chump Mar 3 2012 at 22:13

Your Answer

Not the answer you're looking for? Browse other questions tagged or ask your own question.