A point for any of his followers to keep in mind is that a clinician is not necessarily a trained scientist.
Despite his medical knowledge, his results seem to me to be N=1 at this point, just like the rest of us. He's made amazing personal progress with his health and fitness and that's to be respected. Like many of us, he has a great story about regaining his well-being throgh through paleo.
However, I find it hard to believe that he has had sufficient time to collect the clinical data necessary to support his theories; like many of us, he hasn't been paleo for a long time. A careful clinician will not jump to sweeping conclusions based on a few patients, or just his own results. Blanket statements, erroneous cites, and inchoate postings are not solidifying his position.
Given sufficient and rigorous investigation, some of his ideas could prove to be valid while others go to the dustbin. His leptin prescription does seem to be helping some people based on the testimonials here, and he has a strong passion for all things paleo. He's full of ideas and contributes a lot here, but a clear delineation between fact and speculation when making connections between ideas in the medical and academic literature would be helpful and on the level.