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Statins

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by 0 · March 24, 2014 at 3:41 PM

Hi everyone, I would greatly appreciate help on this topic as it is very personal and important to me. My father has HCM and has a mild build up of calcified plaques (Although the last scan was 8 years ago, he's going to re-test). He is... (more)

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Breefolk 0 · March 24, 2014 at 3:41 PM

Look into l-carnitine supplements. There are several case studies using this supplement along with dietary changes and there has been great improvement in patients with HCM.

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by 229 · June 26, 2013 at 12:02 PM

Does anyone know how this could happen?

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Mscott 0 · May 25, 2013 at 5:25 PM

The inherent definition of a statin is a drug that inhibits the enzyme HMG-CoA reductase. When this enzyme is inhibited you make less farnesyl-pyrophosphate, which itself is used to synthesize both cholesterol (explaining why statins lower... (more)

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by 25 · May 23, 2013 at 10:49 PM

It's been a year since I saw my doctor and I've had another cholesterol test. She is very concerned about the results, which show elevated levels. According to a "risk assessment", I have a 15% chance of cardiovascular event in the next five... (more)

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AxialGentleman 0 · May 18, 2013 at 1:21 AM

Your doctor's chief recommendation will probably be to reduce saturated fat in your diet. Most paleo eaters have some room to do that. e.g., eat leaner meat, don't use quite as much butter, stop eating coconut butter straight out of the jar. You... (more)

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by 1230 · January 17, 2013 at 5:32 AM

Update: VAP results below Age: 24 years old Sex: Male Height: 6'0" Weight: 165 lbs Total Cholesterol: 367 mg/dL HDL: 73 mg/dL Cholesterol/HDL Ratio: 5.03 VLDL: 10 mg/dL LDL: 284 mg/dL Triglycerides: 52 mg/dL My doctor was VERY concerned... (more)

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Janknitz 0 · January 08, 2013 at 9:09 PM

I just read The Great Cholesterol Myth by Bowden and Sinatra. They believe that the only people who should be on statins are men under 65 who have already had one cardiovascular event. You are not in that category, but there are some other... (more)

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by 95 · January 03, 2013 at 6:22 PM

I've heard and read so much about the use of statins and healthy people with high cholesterol, but I can't seem to find anything about the positive effect statins have on people (especially women) who have already suffered a heart attack. Do... (more)

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Roth 0 · December 20, 2012 at 6:10 PM

"High cholesterol" is a disease that only exists in a doctor's office. It's the only disease that requires you to have a doctor. Statins cause diabetes and psychological+hormonal issues.

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by 95 · November 24, 2012 at 7:17 AM

I just finished reading about statins causing Type 2 diabetes.I think it is very interesting that I was on a statin before I had a heart attack, and then I was put on more statins for two years after the heart attack. Over the last two years, one... (more)

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Sataran 0 · November 24, 2012 at 7:17 AM

Statins have been implicated in causing diabetes. But at fairly high doses and for stronger statins like Crestor and Lipitor. This is one of those longer-term side effects of statins which did not come to fore when doing short-term clinical... (more)

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by 50 · October 17, 2012 at 2:58 AM

I've been primal for 13 months now, and in that time I've had my cholesterol checked twice. I am 6'2 and 192 pounds. When I started primal, I was 235 pounds. My blood pressure went from being routinely in the 140/90 range a year ago to 110/70... (more)

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nursling 0 · October 17, 2012 at 2:22 AM

your blood work has you moving in the right direction obviously; why does your doctor want to put you on a statin now that you are showing progress rather than before when you numbers were much worse? your total:HDL ratio has dropped dramatically... (more)

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by 549 · September 06, 2012 at 8:25 PM

To be thorough, some background. 25 yr old male 5'9" 173 lbs Athletic, very active <= 10% bodyfat (by caliper, for whatever it's worth) Low carb high fat/ paleo/ primal (ish) for about 3 months now Very high (>100 mg/dl) lipoprotien(a) levels... (more)

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kev_1 0 · September 06, 2012 at 8:25 PM

They calculate the LDL with a formula: LDL = TC - HDL - 0.2*TC 113 = 193 - 65 - 0.2*76 = 111,8 (not exact because the values of the test are not exact) While the triglyceride and total cholesterol values are exact, the HDL value is an... (more)

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by 20 · August 09, 2012 at 5:40 AM

Hi everyone, I've just returned from a doctor's appointment with lipid panel results, the most important ones, I believe, included below: Total Cholesterol 328 Total LDL-C Direct 183 Total HDL-C Direct 130 Total VLDL-C Direct 15 Total... (more)

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Eric_12 0 · August 09, 2012 at 5:40 AM

LDL of 183 is high... Have you tried removing Butter and cream?

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by 3967 · July 28, 2012 at 8:56 PM

My mother had been taking statins for years and was Type 2 diabetic. She was having extreme muscle pains that made lifting hurt terribly. She runs a daycare so not lifting children up is a major occupational problem. I'm still working on getting... (more)

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Marie 0 · July 28, 2012 at 8:56 PM

Along with all the other comments, don't forget to document your experience w/before and after lab results and the doctor's insistence via phone calls or emails that statins are necessary. Send a detailed letter to his/her supervisor, the... (more)

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by 2198 · September 10, 2012 at 4:50 PM

What are your thoughts on low dose statins for a 83 year old woman with a history of ministrokes and is pre diabetic. She is reluctant to change diet with sweets and fruits, moderates but does not largely eliminated grains. She eats pastured... (more)

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Janknitz 0 · September 10, 2012 at 4:50 PM

Perhaps this article will give you some food for thought: http://people.csail.mit.edu/seneff/alzheimers_statins.html

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by 6849 · July 07, 2012 at 12:08 AM

Does anyone know of any good information (reputable links/studies/etc) on a possible correlation between statin use and vision disturbances/vision loss?

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rht 0 · July 07, 2012 at 12:08 AM

Lipitor lists Amblyopia: Dimness of vision as a potential side effect. niacin also can cause this. start here: http://www.spacedoc.com/statins_eyes

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by 3277 · April 19, 2012 at 3:47 AM

While listening to back Robb Wolf podcasts, he periodically fields a question from someone freaking out about elevated total and LDL. He will then go into a discussion that the friendly fluffy LDL is nothing to worry about. How common is it to... (more)

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Nance 0 · April 19, 2012 at 2:51 AM

This varies widely--some see improvement, some stay the same and some see TC and LDL go quite high. If you're feeling any anxiety about your reactions you should definitely have the test done so you know where you stand. Chris Kresser and Chris... (more)

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by 5100 · April 11, 2012 at 2:58 PM

Some people used to argue that if LDL falls too low, you're susceptible to cancer. It was never very clear to me that this was entirely true. First, how low must your LDL be to be cancer-susceptible? Under 100? Under 50? Second, wouldn't your... (more)

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Lady_Arwen 0 · April 11, 2012 at 2:58 PM

I find it interesting that statins DO NOT REDUCE mortality in most people. In fact, statin users may not die from heart disease, but die from other causes - often cancer! Statins increase risk of diabetes for women, and guess what - diabetics age... (more)

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by 10 · March 20, 2012 at 4:52 AM

Crestor prescription runs out Friday. The earliest I can see my doctor for a refill is Monday. I was going to "get his advice" about going off Crestor for another few days, and then take a blood test (been 99% paleo for 40 days). That would be... (more)

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Dave_16 0 · March 20, 2012 at 12:27 AM

There's never a good reason to NOT go off Crestor. It's a waste of money that is detrimental to your health. End of discussion.

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by 3244 · March 08, 2012 at 12:42 AM

Sorry...I know it's not as simple as that, I'm just frustrated with a conventional medical model in which a number on a report defines a person's state of health and generates a prescription. My mother was just diagnosed as "pre-diabetic". Her... (more)

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rht 0 · March 07, 2012 at 8:09 PM

NNT for primary prevention with statins: http://www.thennt.com/statins-for-heart-disease-prevention-without-prior-heart-disease/ Heart disease risk rises linearly after an A1c of 5.5. She's doing just fine, but details... (more)

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by 20 · February 27, 2012 at 9:49 PM

I don't have the actual numbers yet but the doc tells me my latest blood tests revealed a very high LDL and bad particle size. My CRP is also elevated. He wants me to start taking a statin (Crestor) I had started Paleo, working out, and... (more)

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The_Loon 0 · February 27, 2012 at 9:49 PM

You might want to test certain foods or habits and see if they are inflammatory for you. Have you been to the dentist recently?

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by 851 · February 09, 2012 at 11:03 PM

Anyone read the Jupiter trial? http://www.nejm.org/doi/pdf/10.1056/NEJMoa0807646 I have a patient bring this study to my attention about the effectiveness of statin medications lowering C-reactive protein. His lipid panel is awesome all except he... (more)

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Rose 0 · February 09, 2012 at 11:03 PM

I had an elevated CRP on my last round of labs in June 2011, and my (now ex-) doctor was very concerned about it, despite the rest of my numbers being stellar. My new doctor, a more results-oriented person, apparently, told me she doesn't put much... (more)

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by 851 · July 03, 2012 at 6:20 PM

I have a healthy 45 yo male patient who has been a devout Paleo diet follower for the last 3 months (I've seen his food journal and it's squeeky clean). He decided to have me help him with this initiative so he could get off his statin meds for... (more)

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Mark_34 0 · July 03, 2012 at 6:20 PM

FACTS: Male, white, 52 5-7 170lbs approx. 130lbs fat-free mass Bodyfat: approx. 19% GOAL: <10% bf using a LC PaIeo diet combined with Intermittent Fasting which means I must lose at least 17lbs of bf, both subcutaneous and... (more)

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by 20469 · November 01, 2012 at 6:39 PM

http://news.yahoo.com/statins-well-women-men-study-161754071.html I just saw this 'new study' study. ANyone know how they come up with this conclusion? They say, "In an analysis of 18 clinical trials, researchers found that overall, statins cut... (more)

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HeartBelly 0 · November 01, 2012 at 6:39 PM

What if you are a woman and had a heart attack? What if you changed your diet to Paleo and lost weight. Do you still need statins? What are the indicators and conditions that would give you clearance to get off statins. What supplements such as... (more)

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by 12118 · January 23, 2012 at 4:08 PM

That's the assertion of this article's title: http://www.dailymail.co.uk/health/article-2089099/Breast-cancer-cure-linked-cholesterol-lowering-tablets.html Are there potential confounders at play here? (more)

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Matt_11 0 · January 23, 2012 at 2:15 PM

The fact that these are drugs that are used in hypercholesterolemia is beside the point. They happen to target the mutant p53. It's simply targeting a biosynthetic pathway, shutting it down to prevent cancer growth. Seems like a valid strategy for... (more)

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by 28 · January 12, 2012 at 3:21 PM

I’m hoping for some reassurance that my recent lipid panel numbers are explainable and not reason for panic, and not as my doc suggests, cause for Crestor & niacin. This is going to be long, but I don’t know how to do justice to the question... (more)

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Bill1102inf 0 · January 12, 2012 at 2:49 PM

Lyndra - first, let me congratulate you on awesome lipid #'s. Yes, thats right, they are awesome. Your Dr' has spent too many 'lunches' with the drug reps. IMO, you should NOT take 'crestor'+niacin for your 'high ldl' because, its not high, at... (more)

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by 3854 · December 03, 2011 at 2:41 PM

Here is a study reported in a respected journal. What do you all PH's think of this? http://www.nejm.org/doi/full/10.1056/NEJMoa1110874

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Russ_1 0 · December 03, 2011 at 12:31 PM

Because of the high dose program, it could have been interesting if they had also tested for APOE4 phenotype, conducted periodical cognitive testing, and then run for a longer period than 24 months. Would have liked to seen much deeper... (more)

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by 305 · December 26, 2011 at 9:30 PM

My husband and I recently went in for a consult with a doc who we heard from local paleo loops was pro-paleo. Indeed, he had Cordain's book in the waiting room. After talking with him, I think his partner/son is the more paleo dude, but he was... (more)

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coprophagous 0 · December 26, 2011 at 9:30 PM

statins cause muscle damage. the heart is a muscle. yea good luck with that.

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by 5100 · February 15, 2012 at 7:50 PM

Some people explain away their high LDL by invoking the particle size argument. Those who do low-carb Paleo typically have low triglycerides, which correlate well with Pattern A -- the large, bouncy and fluffy LDL type thought to be harmless. ... (more)

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Bill_18 0 · February 15, 2012 at 7:50 PM

The correlations are not perfect and some numbers may be misleading. First, if you have low TG's, since most values of LDL are calculated using a TG/5 subtraction, if you have low TG's your LDL number will look elevated. There is an alternate... (more)