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Turmeric: anti- and pro-oxidant

by (175)
Updated September 16, 2014 at 8:12 PM
Created August 05, 2013 at 8:01 PM

I was looking into catalase and hydrogen peroxide.

CAT is an enzyme that breaks down H2O2. As we age our production of CAT decreases, and the excess H2O2 does various harms to our bodies, including bleaching of skin and of hair follicles.

Fine.

In India a topical catalase treatment was developed for vitiligo, an unpleasant skin disorder. The treatment didn't work as expected until turmeric (active ingredient curcumin) was removed from the diet: http://www.vitiligo.eu.com/turmeric.php

Wot? Curcumin is an anti-oxidant and boosts catalase. But it looks like the dose Indians typically take in their diet may push it to pro-oxidant behaviour that inhibits catalase. Here's the general view of the two extremes: http://books.google.co.uk/books?id=KJzJ5obKnwwC&pg=PA254&lpg=PA254&dq=curcumin+catalase&source=bl&ots=w-noTZ4b1z&sig=Q7cPhUapJ2onUseyM-WKzZULJc4&hl=en&sa=X&ei=NPf_UdqSK-Xb0QWY64GgCw&ved=0CHUQ6AEwCTgK#v=onepage&q=curcumin%20catalase&f=false

So how much is too much? The most satisfactory answer I could find looks like maybe 6g - a heaped tablespoon? There are 2 studies footnoted, but it's not clear: http://examine.com/supplements/Curcumin/

I take a tip of a teaspoon everyday, so I guess that's well outside the pro-oxidant range.

Anyone else have views? I know turmeric is generally recommended on this site.

(There is a "how much turmeric" thread already, but I think this info deserves a new one. Plus the information on catalase is interesting.)

736662d9fd6314d426cc6de1896aa045
175 · August 06, 2013 at 5:39 PM

And I wonder if curcumin's inhibition of catalase would interest anti-ageing posters.

736662d9fd6314d426cc6de1896aa045
175 · August 06, 2013 at 3:40 PM

I add ground black pepper for piperine. Any views on those studies? The idea of curcumin as pro-oxidant may be new to this forum.

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455 · August 05, 2013 at 10:50 PM

If all you're taking is a tip of a teaspoon, you're probably not getting anything at all because of the poor bioavailability of whole turmeric.

736662d9fd6314d426cc6de1896aa045
175 · August 06, 2013 at 5:39 PM

And I wonder if curcumin's inhibition of catalase would interest anti-ageing posters.

736662d9fd6314d426cc6de1896aa045
175 · August 06, 2013 at 3:40 PM

I add ground black pepper for piperine. Any views on those studies? The idea of curcumin as pro-oxidant may be new to this forum.

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